Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bruce L. Martin"'
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Metallothionein 3 (MT-3), also known as growth inhibitory factor (GIF), exhibits a neuroinhibitory activity. Our lab and others have previously shown that this biological activity involves interacting protein partners in the brain. However, nothing s
Externí odkaz:
https://doaj.org/article/97f1d1f22fec4650a0dce4874f7d37de
Autor:
Robert Hartlage, Brock A. Peters, Igor Nazarenko, Jonathan Baccash, Calvin Kong, Vitali Karpinchyk, Andres Fernandez, Abraham M. Rosenbaum, Ryan J. Cedeno, Paolo Carnevali, Celeste E. McBride, Norman L. Burns, Shaunak Roy, Karen W. Shannon, George M. Church, Snezana Drmanac, Daniel F. Chernikoff, Radoje Drmanac, Geoffrey B. Nilsen, Claudia Richter, Coleen R. Hacker, Jay Shafto, William C. Banyai, Kaliprasad Pothuraju, Helena Perazich, Bruce L. Martin, Dennis G. Ballinger, Benjamin Curson, Linsu Chen, Brian Hauser, Steve Huang, Alexander Wait Zaranek, Anushka Brownley, Dylan Vu, Matt Morenzoni, Andrew B. Sparks, Matthew J. Callow, Alex Cheung, Clifford Reid, Adam P. Borcherding, George Yeung, Xiaodi Wu, Catherine Le, Tom Landers, Aaron L. Halpern, Bahram G. Kermani, Kimberly Perry, Arnold R. Oliphant, Mark Koenig, Charit L. Pethiyagoda, Michel Sun, Joseph V. Thakuria, Conrad G. Sheppy, Anne Tran, Robert E. Morey, Fredrik A. Dahl, Krishna Pant, Karl Mutch, Bryan Staker, Joe Peterson, Jessica Ebert, Yuan Jiang, Jia Liu, Razvan Chirita, Uladzislau Sharanhovich
Publikováno v:
Science. 327:78-81
Toward $1000 Genomes The ability to generate human genome sequence data that is complete, accurate, and inexpensive is a necessary prerequisite to perform genome-wide disease association studies. Drmanac et al. (p. 78 , published online 5 November) p
Publikováno v:
Experimental Biology and Medicine. 231:1500-1506
>> Metallothionein (MT)-3, originally called growth inhibitory factor (GIF), was initially identified through its ability to inhibit the growth of neuronal cells in the presence of brain extract. MT-3 is the brain specific isoform of the MT family wh
Publikováno v:
The Protein Journal. 25:175-182
The Homology module within Insight-II was used to model residues 374-420, sequences missing in the coordinates of resolved structure of the catalytic subunit of calcineurin. The modeling was done in two segments. The calmodulin binding region from re
Publikováno v:
Protein Science. 14:1151-1157
Using immunological approaches and mass spectrometry, five proteins associated with metallothionein-3 in mouse brains have been identified. Metallothionein-3 and associated proteins were isolated using immunoaffinity chromatography over immobilized a
Publikováno v:
Protein & Peptide Letters. 11:149-158
para-Nitrophenyl phosphorothioate (pNPT) was hydrolyzed by calcineurin at initial rates slightly, but comparable to rates for para-nitrophenyl phosphate (pNPP). Kinetic characterization yielded higher estimates for both Km and Vmax compared to pNPP.
Autor:
Cheryl Bartleson, Bruce L. Martin, David J. Rhode, Donna J. Spannaus-Martin, Jennifer Imparl-Radosevich
Publikováno v:
Protein Expression and Purification. 26:194-201
Recombinant calcineurin heterodimer with the full length delta-isoform of the catalytic subunit (CaN(500)) was expressed in insect cells using the baculovirus system and compared to native bovine brain enzyme in its response to divalent metal ions, r
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1480:23-28
Synthetic peptides based on residues 9 to 18 of glycogen phosphorylase were prepared containing citrulline at position 10 or 16, or at both positions 10 and 16. The peptides were compared as substrates for a recombinant, truncated form of the catalyt
Autor:
Bruce L. Martin
Publikováno v:
Bioorganic Chemistry. 28:17-27
Kinetic parameters for the metal ion activation of calcineurin at 30°C were found to be correlated to the formation constants (log K 1 ) of the activating metal ions (Mn 2+ , Co 2+ , Ni 2+ , Zn 2+ , and Mg 2+ ) with the substrate para -nitrophenyl p