Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Bruce L. Currie"'
Autor:
Bruce L. Currie, Michael E. Johnson
Publikováno v:
Current Medicinal Chemistry. 1:418-422
Sickle cell anemia is a genetic disease that affects a large number of people throughout the world. This disease is very well understood at the molecular level, but for which there is still no effective treatment or cure. Phenylalanine, a natural ami
Autor:
Zhao Lan Lin, Michelle del Rosario-Chow, Michael E. Johnson, John L. Krstenansky, Jiraporn Ungwitayatorn, Wen Sing Sheu, Yu Hwei Lee, Bruce L. Currie
Publikováno v:
Tetrahedron. 49:3489-3500
If the important functional groups of a biologically active peptide can be arrayed on a non-peptide framework in the “biologically active conformation” it may be possible to maximize the receptor interaction and eliminate or reduce the number of
Publikováno v:
Synthetic Communications. 23:531-534
A convenient method has been developed to selectivly form the monotriphenylmethyl derivatives of symmetric 1,n-diols, both straight chain and cyclic, in moderate to high yields.
Publikováno v:
ChemInform. 22
A convenient synthesis of 5-bromotryptophan and protected intermediates for peptide synthesis is reported. Only three steps are required to convert ethyl pyruvate into 5-bromo-tryptophan ethyl ester.
Publikováno v:
ChemInform. 22
Autor:
J. N. Patel, Noojaree Prasitpan, Michael E. Johnson, P. Manavalan, P. Z. De Croos, Bruce L. Currie, B. L. Stockwell, Leela Kar
Publikováno v:
ChemInform. 23
Publikováno v:
ChemInform. 23
Publikováno v:
ChemInform. 25
A convenient method has been developed to selectivly form the monotriphenylmethyl derivatives of symmetric 1,n-diols, both straight chain and cyclic, in moderate to high yields.
Publikováno v:
Journal of Heterocyclic Chemistry. 29:707-711
The synthesis of the syn- 14 and anti- 13 isomers of 2(S)-phthalimidornethyl-2,3,4,4a,7,7a-hexahydro-6-oxo-5H-pyrano[2,3-b]pyrrole was accomplished starting from sodium 3,4-dihydro-2H-pyran-2-carboxylate. The isomers were separated by preparative hig
Autor:
Parthasarathy Manavalan, Michael E. Johnson, Bruce L. Currie, Brenda L. Stockwell, Philomen Z. De Croos, Jayeshkumar N. Patel, Noojaree Prasitpan, Leela Kar
Publikováno v:
Journal of Heterocyclic Chemistry. 29:335-341
A series of N-1 or C-2 phenylalkyl substituted tryptophans and C-1 phenylalkyl substituted 3,4-dihydro-β-carbolines were prepared from the apropriate aniline, 1b or 1e, or tryptophan, 8 or 11, by ring closure methods. None of the compounds prepared