Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Bruce L Booth"'
Autor:
Robert Langer, John M. Maraganore, David P. Schenkein, Neil Warma, Chris Adams, Chip Clark, Mark Levin, William Rastetter, Bruce A Leicher, Nancy A Thornberry, Robert I Blum, Jonathan G Rosin, Kleanthis G Xanthopoulos, Timothy D. Harris, Jeff L Cleland, Robert Forrester, Nancy Simonian, Peter Barrett, Stephen Bloch, William J Rieflin, Brian M Gallagher, Lewis Rusty Williams, Doug Doerfler, Richard Ulevitch, David R. Liu, Andrew Levin, P. Grint, Nick J Simon, Pablo J Cagnoni, Daphne Zohar, Kush M Parmar, Guy Macdonald, Corey M McCann, Stelios Papadopoulos, Michael D Clayman, Diego Miralles, Paula Cobb, John Diekman, Jeremy M Levin, Amir Nashat, Samuel G Waksal, Rachel King, Sandford Sandy Zweifach, Gail J Maderis, Ankit Mahadevia, Heather Franklin, Cary G Pfeffer, Steven K Brauer, Akshay Vaishnaw, Clay B. Siegall, Howard Furst, Jonathan S Leff, William J Rutter, Dennis J. Purcell, Mary T Szela, J C Gutierrez-Ramos, Sean A McCarthy, Elizabeth Lr Donley, Yaron Werber, Doug E Williams, Christoph Westphal, Paul Sekhri, W Eddie Martucci, Jeb Keiper, John E Osborn, Simba Gill, Bassil Dahiyat, Steven H Holtzman, Annalisa Jenkins, Saurabh Saha, Matthew J. During, Camille Samuels, Mara G Aspinall, Chad Robins, Jason P Rhodes, Herve Hoppenot, Jeff Kaplan, Michael A Narachi, Amit Rakhit, Julia C Owens, Steve M Paul, Martin Varsavsky, Mark G. Currie, Rajeev Shah, Rob Perez, H. Stewart Parker, Jeff Stein, Leonard Patrick Gage, Perry Karsen, Joel F Martin, Bob More, Matthew Perry, James G McArthur, Gregory J Flesher, Martin Tolar, Andrew Schwab, James A Geraghty, Eric L Dobmeier, Brook Byers, Vanessa King, Mason W. Freeman, Larry Miller, Marco Taglietti, Jeff Albers, Neil A Exter, Michael W Bonney, Ron Cohen, Nick Leschly, Bruce L Booth, William J Newell, Peter Kolchinsky, Ryan J Watts, Paul Laikind, Andrew G. Myers, Cedric Francois, Stephen T Isaacs, Scott Koenig, Michel Vounatsos, Tuan Ha-Ngoc, Nicholas Galakatos, George P Vlasuk, Isaac Ciechanover, Jeff Kindler, Brian M. Cali, Matthew R Patterson, Kenneth I Moch, Tom Graney, Martin Babler, Jonathan J Fleming, Mark A Goldsmith, Daniel M Bradbury, John Mendlein, Mike Powell, Nessan Bermingham, Eric Elenko, H. Robert Horvitz, Yujiro Steve Hata, Mark Pruzanski, Faheem Hasnain, Henri A. Termeer, Maxine Gowen, Scott M Rocklage, Anne VanLent, Thomas Shenk, Leslie Henshaw, Jeff Jonker, Nina Kjellson, Deborah Dunsire, Zoe Barry, Ron C Renaud, Alex Martin, Uri Lopatin, George Scangos, Jean Kim, Kartik Ramamoorthi, Michael Rosenblatt, Nagesh K Mahanthappa, Harvey F. Lodish, Paul B Bolno, Wendell Wierenga, Atul Pande, Barry Greene, Alan Levy, Adrian Ad Rawcliffe, Wende S Hutton, C Geoffrey McDonough, Vicki L. Sato, Jean-Francois Formela, David V. Goeddel, Bill Haney, Rich Heyman, James E Audia, Ron Cooper, Nina Tandon, Brett Ahrens, Julian Adams, Peter Hecht, John J Lee, Stuart L. Schreiber, Laurence E Reid, Bernat Olle, Paul Hastings, John A. Scarlett, Michael Su, David Grayzel, Ted W Love, Arnold J. Levine, Gerhard Koenig, Thomas E Hughes, Jens W Eckstein, Wendy Nelson, Vikas Goyal
Publikováno v:
Nature Biotechnology. 35:204-206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2d10770c0eb9d17bb770366663a693
https://doi.org/10.1038/nbt.3824
https://doi.org/10.1038/nbt.3824
Autor:
Bruce L Booth
Publikováno v:
Nature biotechnology. 34(1)
The markets may be softening on biotech, but overall the sector remains in an incredibly strong environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacb31e3b14237e0938a8f34f0e724d0
https://pubmed.ncbi.nlm.nih.gov/26744974
https://pubmed.ncbi.nlm.nih.gov/26744974
Autor:
Bijan Salehizadeh, Bruce L Booth
Publikováno v:
Nature Biotechnology. 29:579-583
Contrary to widely held perceptions, data on venture returns show that life sciences startups have outperformed other sectors over the past decade.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16de7db8265f396f7ac63de0af57a208
https://doi.org/10.1038/nbt.1908
https://doi.org/10.1038/nbt.1908
Autor:
Bruce L Booth
Publikováno v:
Nature Biotechnology. 24:1335-1340
Contrary to conventional thinking, there are compelling reasons for investors to consider early-stage life science ventures, especially in the context of a maturing biotech business 'ecosystem'.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b3a3502f41085f9521d0c1e18ab9c1
https://doi.org/10.1038/nbt1106-1335
https://doi.org/10.1038/nbt1106-1335
Autor:
Bruce L Booth, Rodney W. Zemmel
Publikováno v:
Nature Reviews Drug Discovery. 3:451-456
Long-term declines in the productivity of pharmaceutical R&D threaten the sustainability of the current business model. A major driver of the decline has been the rising cost, and increased rate of failure, of projects across the industry, caused in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d45f8a87d86f00367b904f344010ad0
https://doi.org/10.1038/nrd1384
https://doi.org/10.1038/nrd1384
Publikováno v:
Viral Immunology. 15:193-196
Cytotoxic T lymphocytes (CTLs) play a key role in the control of persistent viral infections. Differences in the quality of this cellular immune response influence the long-term outcome of such infections, but the factors that determine which virus-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f3e0da02f1766657bd914bba4c40d3e
https://doi.org/10.1089/088282402317340332
https://doi.org/10.1089/088282402317340332
Autor:
Andrew K. Sewell, David A. Price, Helene Teisserenc, Bruce L. Booth, Uzi Gileadi, Fiona M. Flavin, John Trowsdale, Rodney E. Phillips, Vincenzo Cerundolo
Publikováno v:
The Journal of Immunology. 162:7075-7079
The proteasome, an essential component of the ATP-dependent proteolytic pathway in eukaryotic cells, is responsible for the degradation of most cellular proteins and is believed to be the main source of MHC class I-restricted antigenic peptides for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d99b80d57bd4c953dddad784fe299c
https://doi.org/10.4049/jimmunol.162.12.7075
https://doi.org/10.4049/jimmunol.162.12.7075
Autor:
Marc Bonneville, Rolf M. Zinkernagel, Marcus Groettrup, Bruce L. Booth, Patrice Andre, Paul Klenerman, Vincenzo Cerundolo, Francine Jotereau, R de Giuli, Vincent Lotteau
Publikováno v:
Proceedings of the National Academy of Sciences. 95:13120-13124
Inhibitors of the protease of HIV-1 have been used successfully for the treatment of HIV-1-infected patients and AIDS disease. We tested whether these protease inhibitory drugs exerted effects in addition to their antiviral activity. Here, we show in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd040059615ffcd4126b5c8bfaafb254
https://doi.org/10.1073/pnas.95.22.13120
https://doi.org/10.1073/pnas.95.22.13120
Autor:
Bruce L Booth
Publikováno v:
Nature biotechnology. 27(8)
After a decade of significant challenges, biotech's long-term sustainability depends on making fundamental changes to its traditional business model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271ab651e8e5ed6c79ca74a0992aff87
https://pubmed.ncbi.nlm.nih.gov/19816436
https://pubmed.ncbi.nlm.nih.gov/19816436
Autor:
Bruce L Booth
Publikováno v:
Nature biotechnology. 25(8)
An analysis of recent returns from venture-backed biotech firms reveals that companies receiving the most financing do not necessarily deliver the best returns.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d25f703b27d8a7782641c6e796d20fb
https://pubmed.ncbi.nlm.nih.gov/17687357
https://pubmed.ncbi.nlm.nih.gov/17687357