Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Bruce K. Krueger"'
Publikováno v:
bioRxiv
There is an increased incidence of autism among the children of women who take the anti-epileptic, mood stabilizing drug, valproic acid (VPA) during pregnancy; moreover, exposure to VPAin uterocauses autistic-like symptoms in rodents and non-human pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242bc46d540f75a72a2054a38f43e616
https://europepmc.org/articles/PMC10187231/
https://europepmc.org/articles/PMC10187231/
Publikováno v:
Developmental neuroscience. 39(6)
Prenatal exposure to the antiepileptic, mood-stabilizing drug, valproic acid (VPA), increases the incidence of autism spectrum disorders (ASDs); in utero administration of VPA to pregnant rodents induces ASD-like behaviors such as repetitive, stereot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989f9ae9ea7c633cd66f858796ad58da
https://pubmed.ncbi.nlm.nih.gov/29073621
https://pubmed.ncbi.nlm.nih.gov/29073621
Autor:
H. R. Zielke, Peter E. Murray, Luis E.F. Almeida, Clinton D. Roby, Bruce K. Krueger, Tami J. Kingsbury
Publikováno v:
The Journal of Neuroscience. 29:12702-12710
cAMP can stimulate the transcription of many activity-dependent genes via activation of the transcription factor, cAMP response element-binding protein (CREB). However, in mouse cortical neuron cultures, prior to synaptogenesis, neither cAMP nor dopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf54b1f4ccf24eaf4e865ceef1475c04
https://doi.org/10.1523/jneurosci.1166-09.2009
https://doi.org/10.1523/jneurosci.1166-09.2009
Publikováno v:
Journal of Neurochemistry. 103:761-770
Cyclic AMP response element binding protein (CREB) functions as an activity-dependent transcription factor in the nervous system. Increases in intracellular Ca(2+) due to neuronal activity lead to the phosphorylation and subsequent activation of CREB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda58a3ab7678a69666daeac85429ecd
https://doi.org/10.1111/j.1471-4159.2007.04801.x
https://doi.org/10.1111/j.1471-4159.2007.04801.x
Publikováno v:
Annals of the New York Academy of Sciences. 746:480-484
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f00661c9747a710a51232a84b75e68
https://doi.org/10.1111/j.1749-6632.1994.tb39291.x
https://doi.org/10.1111/j.1749-6632.1994.tb39291.x
Autor:
Bruce K. Krueger, Krish Chandrasekaran, Christopher L. Wright, Zara Mehrabian, Linda L. Bambrick, Gary Fiskum
Publikováno v:
Journal of Bioenergetics and Biomembranes. 38:43-47
Isolated brain mitochondria are a heterogeneous mixture from different cell types and these subsets may have differing sensitivities to Ca2+-induced membrane permeability transition (MPT) and to inhibition of the MPT by cyclosporin A (CsA). This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a884535f87a887e6c2c6c14eece9fe38
https://doi.org/10.1007/s10863-006-9004-7
https://doi.org/10.1007/s10863-006-9004-7
Publikováno v:
European Journal of Neuroscience. 21:3251-3261
GABA(A) receptor activation during brain development is a critical source of excitation. This is due to the positive equilibrium potential for chloride relative to resting membrane potential, resulting in membrane depolarization sufficient to open vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0a8317c560e6f79c3014bcb633998d
https://doi.org/10.1111/j.1460-9568.2005.04175.x
https://doi.org/10.1111/j.1460-9568.2005.04175.x
Publikováno v:
Developmental Neuroscience. 26:255-265
During embryonic development of the mammalian cerebral cortex, the generation of the marginal zone (MZ) and subplate (SP) precedes that of the cortical plate (CP). MZ and SP neurons are believed to play a ‘pioneering’ role in directing the organi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bab61c483d4777f39f6274efd78083
https://doi.org/10.1159/000082142
https://doi.org/10.1159/000082142
Publikováno v:
Journal of Biological Chemistry. 278:40744-40748
The neurotrophin brain-derived neurotrophic factor (BDNF), via activation of its receptor, tyrosine receptor kinase B (trkB), regulates a wide variety of cellular processes in the nervous system, including neuron survival and synaptic plasticity. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1688482191064e76947527350765bf
https://doi.org/10.1074/jbc.m303082200
https://doi.org/10.1074/jbc.m303082200
Altered astrocyte calcium homeostasis and proliferation in theTs65Dn mouse, a model of Down syndrome
Publikováno v:
Journal of Neuroscience Research. 73:89-94
Genes from the Down syndrome (DS) critical region of human chromosome 21, which contribute to the pathology of DS, are also found on mouse chromosome 16. Several animal models of DS with triplication of genes from the DS critical region have been gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213907e0dac91df821ab5c753c08ac8b
https://doi.org/10.1002/jnr.10630
https://doi.org/10.1002/jnr.10630