Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bruce J. Darrow"'
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Akers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-16 (2019)
Abstract Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511
Externí odkaz:
https://doaj.org/article/a76b99477ddb49caaac1147906552dfc
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Ayers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-1 (2019)
Externí odkaz:
https://doaj.org/article/4821428476ee4beaa78f0a9545cce053
Autor:
Kenny Chu, Joseph Sweeny, Nitin Barman, Brian Wasielewski, Jacqueline E. Tamis-Holland, Ugo Ezenkwele, George Dangas, Bruce J. Darrow, Haydee Garcia, Matthew Bai, Abraham Warshaw, Jeffrey Bander, Umesh Gidwani, Atul Kukar, Samin K. Sharma, Manjit Singh, Beth Oliver, Georgios Syros, Annapoorna Kini, Parasuram Krishnamoorthy, Yuliya Vengrenyuk, Andriy Vengrenyuk, Usman Baber
Publikováno v:
European Heart Journal - Digital Health. 2:189-201
Aims Technological advancements have transformed healthcare. System delays in transferring patients with ST-segment elevation myocardial infarction (STEMI) to a primary percutaneous coronary intervention (PCI) centre are associated with worse clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca613c68720a9bf8066709a3eb87a439
https://doi.org/10.1093/ehjdh/ztab010
https://doi.org/10.1093/ehjdh/ztab010
Publikováno v:
Annals of emergency medicine. 79(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f29993f3486d9df4cc15abab2355c2a
https://pubmed.ncbi.nlm.nih.gov/34607740
https://pubmed.ncbi.nlm.nih.gov/34607740
Autor:
Johan Björkegren, Rong Chen, Arno Ruusalepp, Letizia Amadori, Kipp W. Johnson, Benjamin S. Glicksberg, Nicholas K. Akers, Li Li, Christer Betsholtz, Chiara Giannarelli, Khader Shameer, Gillian M. Belbin, Marcus A. Badgeley, Ben Readhead, Hongxia Ren, Kristin L. Ayers, Oscar Franzén, Katyayani Sukhavasi, Bruce J. Darrow, Jason C. Kovacic, Josefin Skogsberg, Eimear E. Kenny, Joel T. Dudley, Eric E. Schadt, Shuyu D. Li, Raili Ermel
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-1 (2019)
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-1 (2019)
Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511 individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff92adecb637039a739a9b8cb0711b6
https://doi.org/10.1186/s12920-019-0573-9
https://doi.org/10.1186/s12920-019-0573-9
Autor:
Kipp W. Johnson, Oscar Franzén, Joel T. Dudley, Katyayani Sukhavasi, Josefin Skogsberg, Eric E. Schadt, Arno Ruusalepp, Johan Björkegren, Li Li, Ben Readhead, Raili Ermel, Chiara Giannarelli, Rong Chen, Hongxia Ren, Letizia Amadori, Kristin L. Akers, Bruce J. Darrow, Gillian M. Belbin, Jason C. Kovacic, Eimear E. Kenny, Shuyu D. Li, Benjamin S. Glicksberg, Nicholas K. Akers, Christer Betsholtz, Khader Shameer, Marcus A. Badgeley
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-16 (2019)
BMC Medical Genomics
BMC Medical Genomics
Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511 individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e553347c82a189c4bcdc41e31671239
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-391365
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-391365
Autor:
Samin K. Sharma, Yuliya Vengrenyuk, Manjit Singh, Usman Baber, Andriy Vengrenyuk, Kenny Chu, Annapoorna Kini, Matthew Bai, Umesh Gidwani, Jeffrey Bander, Atul Kukar, George Dangas, Valentin Fuster, Brian Wasielewski, Parasuram Krishnamoorthy, Ugo Ezenkwele, Beth Oliver, Bruce J. Darrow, Georgios Syros, Nitin Barman, Sudipto Srivastava, Jacqueline E. Tamis-Holland, Joseph Sweeny, Abraham Warshaw
Publikováno v:
Journal of the American College of Cardiology. 77:3245
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aeec494f8e74e8b34b4ca80d03796ff
https://doi.org/10.1016/s0735-1097(21)04599-x
https://doi.org/10.1016/s0735-1097(21)04599-x
Publikováno v:
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 78:583-589
Although cardiovascular disease is a major cause of mortality, morbidity, and healthcare expense in the United States, diagnosis in elderly patients, especially those who are asymptomatic, can be challenging. Noninvasive testing offers an opportunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbab569820e258429ba3cd6dc504dd71
https://doi.org/10.1002/msj.20273
https://doi.org/10.1002/msj.20273
Autor:
Eric C. Beyer, Jeffrey E. Saffitz, Stephen M. Dodge, Bruce J. Darrow, Michael A. Beardslee, Karen G. Green
Publikováno v:
Journal of the American College of Cardiology. 32(3):800-807
Objectives. To elucidate signal transduction pathways regulating expression of myocardial gap junction channel proteins (connexins) and to determine whether mediators of cardiac hypertrophy might promote remodeling of gap junctions, we characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558ffe1c5215a59c17fc989173391ccf
Publikováno v:
Circulation Research. 76:381-387
Abstract Three gap junction proteins have been identified in mammalian cardiac myocytes: connexin43 (Cx43), connexin45 (Cx45), and connexin40 (Cx40). These proteins form channels with different electrophysiological properties and have different distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceb687aabaf4852b8dbd0fdf5e8e6ba
https://doi.org/10.1161/01.res.76.3.381
https://doi.org/10.1161/01.res.76.3.381