Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bruce H. Sells"'
Autor:
Dawn E. Larson, Ross D. Hannan, Bruce H. Sells, Laura Taylor, Marija Glibetic, Lawrence I. Rothblum
Publikováno v:
Journal of Biological Chemistry. 270:4209-4212
Transcription of the ribosomal RNA genes by RNA polymerase I is tightly coordinated with the rate of cell growth. The RNA polymerase I transcription factor, UBF, activates transcription by binding to elements within the promoter and enhancer elements
Autor:
Daniel J. O'Mahony, Dawn E. Larson, Bruce H. Sells, Marija Glibetic, Lawrence I. Rothblum, WenQin Xie
Publikováno v:
Proceedings of the National Academy of Sciences. 90:7933-7936
rRNA synthesis decreases significantly during the differentiation of rat L6 myoblasts to myotubes. Nuclear run-on assays demonstrated that the decrease was attributable to decreased rates of rRNA gene transcription. Immunoblot analysis indicated a ma
Autor:
Lloyd C. Berger, Bruce H. Sells
Publikováno v:
Biochemistry and Cell Biology. 70:528-534
Following serum stimulation of quiescent 3T6 cells, an elevated in vivo rate of translation was observed. These studies were designed to identify the proteins associated with polysomal mRNA under different growth conditions in an attempt to establish
Publikováno v:
Europe PubMed Central
Various proteins required for the initiation of eukaryotic gene transcription by RNA polymerase II have been identified and characterized, but little is known about their organization into a functional unit. Here, we describe the appearance of the mu
Publikováno v:
Biochemical Society Transactions. 19:1099-1103
Publikováno v:
FEBS Letters. 286:163-166
Studies have been initiated to identify the protein component(s) which interact with the beta regulatory region of the mouse ribosomal protein L32 gene promoter. By the combined use of the mobility shift assay and UV cross-linking, a factor specific
Publikováno v:
Biochemistry and Cell Biology. 69:5-22
Ribosome biogenesis in eucaryotic cells involves the coordinated synthesis of four rRNA species, transcribed by RNA polymerase I (18S, 28S, 5.8S) and RNA polymerase III (5S), and approximately 80 ribosomal proteins translated from mRNAs synthesized b
Publikováno v:
Molecular and cellular endocrinology. 167(1-2)
Incubation of rat L6 myoblasts for 24 h with 10(-7) M dexamethasone, a glucocorticoid analogue, resulted in a 2.5-fold increase in the rate of ribosomal protein L32 (rpL32) gene transcription with a corresponding increase in the level of rpL32 mRNA.
Publikováno v:
Experimental cell research. 227(1)
To extend our understanding of the mechanisms regulating ribosome biosynthesis during changes in cellular growth rate, the expression and subcellular distribution of U3 snRNA and one of its associated proteins, fibrillarin, were examined in mouse 3T6
Publikováno v:
Molecular and cellular endocrinology. 94(2)
The glucocorticoid analogue, dexamethasone, stimulated RNA synthesis more than two-fold in rat L6 myoblasts, without affecting the rate of cell proliferation. Treatment of myoblasts for 24 h with 10(-7) M dexamethasone resulted in a 30% increase in t