Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bruce Grasberger"'
Autor:
Yi Liu, Jichun Ma, Renee L. DesJarlais, Rebecca Hagan, Jason Rech, Changlu Liu, Robyn Miller, Jeffrey Schoellerman, Jinquan Luo, Michael Letavic, Bruce Grasberger, Michael P. Maher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed in the nervous system. ASIC gating is modulated by divalent cations as well as small molecules; however, the molecular determinants of gating modulation by d
Externí odkaz:
https://doaj.org/article/7532453b22314d01ada9b275f434a0b8
Autor:
Yi Liu, Jichun Ma, Renee L. DesJarlais, Rebecca Hagan, Jason Rech, David Lin, Changlu Liu, Robyn Miller, Jeffrey Schoellerman, Jinquan Luo, Michael Letavic, Bruce Grasberger, Michael Maher
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Liu et al study the molecular and structural mechanism of the modulation of ASIC1 channel gating using functional, crystallographic, computational and mutational approaches. They identify small molecules that allosterically stabilize the closed state
Externí odkaz:
https://doaj.org/article/cd6928ca293c4d9a8cd20517994d727a
Publikováno v:
Protein Science. 3:15-21
The backbone dynamics of the immunoglobulin-binding domain (B1) of streptococcal protein G, uniformly labeled with 15N, have been investigated by two-dimensional inverse detected heteronuclear 1H-15N NMR spectroscopy at 500 and 600 MHz. 15N T1, T2, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d8971a59869644ba45bed497fcf4a9e
https://doi.org/10.1002/pro.5560030103
https://doi.org/10.1002/pro.5560030103
Autor:
Céline, Schalk-Hihi, Carsten, Schubert, Richard, Alexander, Shariff, Bayoumy, Jose C, Clemente, Ingrid, Deckman, Renee L, DesJarlais, Keli C, Dzordzorme, Christopher M, Flores, Bruce, Grasberger, James K, Kranz, Frank, Lewandowski, Li, Liu, Hongchang, Ma, Diane, Maguire, Mark J, Macielag, Mark E, McDonnell, Tara, Mezzasalma Haarlander, Robyn, Miller, Cindy, Milligan, Charles, Reynolds, Lawrence C, Kuo
Publikováno v:
Protein science : a publication of the Protein Society. 20(4)
A high-resolution structure of a ligand-bound, soluble form of human monoglyceride lipase (MGL) is presented. The structure highlights a novel conformation of the regulatory lid-domain present in the lipase family as well as the binding mode of a pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b2e8c9197ef4514b5cff96864bf7279
https://pubmed.ncbi.nlm.nih.gov/21308848
https://pubmed.ncbi.nlm.nih.gov/21308848
Publikováno v:
Journal of molecular biology. 230(2)
The backbone dynamics of the cytokine interleukin-8, a symmetric homodimer of overall molecular mass 16 kDa, has been investigated at pH 5.2 by means of 15N relaxation measurements using heteronuclear two-dimensional inverse detected 1H-15N spectrosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5807009636cd92b98055dfc18e9e300d
https://pubmed.ncbi.nlm.nih.gov/8464050
https://pubmed.ncbi.nlm.nih.gov/8464050
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 83(17)
We present a conceptual framework for evaluating the effect on the self-association of proteins in membranes due to the presence of other proteins at high concentrations (excluded volume effect) and the high concentration and preoriented state of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7251ae4532306a475478b358e20fb3f
https://pubmed.ncbi.nlm.nih.gov/3018721
https://pubmed.ncbi.nlm.nih.gov/3018721
Autor:
Jean-Pierre Kinet, Bruce Grasberger
Publikováno v:
Subcellular Biochemistry ISBN: 9781461393641
This chapter focuses on the reconstitution of the Fee receptor with high affinity for immunoglobulin E (FcєRI). This receptor is found exclusively on mast cells, basophils, and related cells. Its aggregation initiates the release of mediators respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60cfabccca631a3a413e8f8520889ea
https://doi.org/10.1007/978-1-4613-9362-7_8
https://doi.org/10.1007/978-1-4613-9362-7_8
