Výsledky vyhledávání - "Bruce G. Lyeth"

Akademický článek

Electrical Guidance of Human Stem Cells in the Rat Brain

Autor: Jun-Feng Feng, Jing Liu, Lei Zhang, Ji-Yao Jiang, Michael Russell, Bruce G. Lyeth, Jan A. Nolta, Min Zhao

Publikováno v: Stem Cell Reports, Vol 9, Iss 1, Pp 177-189 (2017)

Limited migration of neural stem cells in adult brain is a roadblock for the use of stem cell therapies to treat brain diseases and injuries. Here, we report a strategy that mobilizes and guides migration of stem cells in the brain in vivo. We develo

Externí odkaz: https://doaj.org/article/0e580e0ee2c34c819d5d1c6886f634c2

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Combined Inhibition of Fyn and c-Src Protects Hippocampal Neurons and Improves Spatial Memory via ROCK after Traumatic Brain Injury

Autor: Zhouheng Ye, Ali Izadi, Gene G. Gurkoff, Kaitlin Rickerl, Frank R. Sharp, Bradley P. Ander, Sawyer Z. Bauer, Austin Lui, Bruce G. Lyeth, DaZhi Liu

Publikováno v: J Neurotrauma
Journal of neurotrauma, vol 39, iss 7-8

Our previous studies demonstrated that traumatic brain injury (TBI) and ventricular administration of thrombin caused hippocampal neuron loss and cognitive dysfunction via activation of Src family kinases (SFKs). Based on SFK localization in brain, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b9279ff84ff5044d8606f779db81c7
https://pubmed.ncbi.nlm.nih.gov/35109711

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Akademický článek

Sex and Electrode Configuration in Transcranial Electrical Stimulation

Autor: Michael J. Russell, Theodore A. Goodman, Joseph M. Visse, Laurel Beckett, Naomi Saito, Bruce G. Lyeth, Gregg H. Recanzone

Publikováno v: Frontiers in Psychiatry, Vol 8 (2017)

Transcranial electrical stimulation (tES) can be an effective non-invasive neuromodulation procedure. Unfortunately, the considerable variation in reported treatment outcomes, both within and between studies, has made the procedure unreliable for man

Externí odkaz: https://doaj.org/article/0991371425c14646bd69889f7154204c

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Akademický článek

Historical Review of the Fluid Percussion TBI Model

Autor: Bruce G Lyeth

Publikováno v: Frontiers in Neurology, Vol 7 (2016)

Abstract:Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past

Externí odkaz: https://doaj.org/article/3805515808554ba9be1ee1da5d72ec9f

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Outcome measures from experimental traumatic brain injury in male rats vary with the complete temporal biomechanical profile of the injury event

Autor: Bryan J. Pfister, Mathew Long, Rafael Ordaz, Radia Abdul-Wahab, Bruce G. Lyeth

Publikováno v: Journal of Neuroscience Research. 98:2027-2044

Millions suffer a traumatic brain injury (TBI) each year wherein the outcomes associated with injury can vary greatly between individuals. This study postulates that variations in each biomechanical parameter of a head trauma lead to differences in h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016d7cbd2f8bd0c1c71624af63b4bf4d
https://doi.org/10.1002/jnr.24670

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Akademický článek

Gender differences in current received during transcranial electrical stimulation

Autor: Michael eRussell, Theodore eGoodman, Qiang eWang, Bennett eGroshong, Bruce G Lyeth

Publikováno v: Frontiers in Psychiatry, Vol 5 (2014)

Low current transcranial electrical stimulation is an effective but somewhat inconsistent tool for augmenting neuromodulation. In this study, we used 3D MRI guided electrical transcranial stimulation (GETS) modeling to estimate the range of current i

Externí odkaz: https://doaj.org/article/1e9ae440ee9a4c47adf583a57d61ec11

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Functional interferometric diffusing wave spectroscopy of the human brain

Autor: Vivek J. Srinivasan, Mingjun Zhao, Lara Zimmermann, Ryan Martin, Bruce G. Lyeth, Wenjun Zhou, Jun Zhu, Oybek Kholiqov

Publikováno v: Science Advances
Science advances, vol 7, iss 20

New technology noninvasively monitors cerebral blood flow index and brain function in adult humans.
Cerebral blood flow (CBF) is essential for brain function, and CBF-related signals can inform us about brain activity. Yet currently, high-end me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8cf07b4c1719e84fafb9cad30c80f2
http://europepmc.org/articles/PMC8115931

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Mechanical injury and blood are drivers of spatial memory deficits after rapid intraventricular hemorrhage

Autor: Janet A. Keiter, Kimia Kamal, Bruce G. Lyeth, Audrey R. Vergara, Frank R. Sharp, Tamar R. Binyamin, Ben Waldau, Ali Izadi, Cameron W. Hawk, Joyce N. de la Cruz Dapula, Gene G. Gurkoff

Publikováno v: Neurobiol Dis
Neurobiology of Disease, Vol 145, Iss, Pp 105084-(2020)

Aneurysmal intraventricular hemorrhage (IVH) survivors may recover with significant deficits in learning and memory. The goal of this study was to investigate the mechanism of memory decline after intraventricular aneurysm rupture. We developed an an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6248f63ed8eb0de0b3b673e7b72578
https://pubmed.ncbi.nlm.nih.gov/32941979

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Electrical Guidance of Human Stem Cells in the Rat Brain

Autor: Min Zhao, Jing Liu, Bruce G. Lyeth, Lei Zhang, Jun Feng Feng, Ji Yao Jiang, Michael J. Russell, Jan A. Nolta

Publikováno v: Stem Cell Reports
Stem cell reports, vol 9, iss 1
Stem Cell Reports, Vol 9, Iss 1, Pp 177-189 (2017)
Feng, JF; Liu, J; Zhang, L; Jiang, JY; Russell, M; Lyeth, BG; et al.(2017). Electrical Guidance of Human Stem Cells in the Rat Brain. Stem Cell Reports, 9(1), 177-189. doi: 10.1016/j.stemcr.2017.05.035. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/78t424mv

Summary Limited migration of neural stem cells in adult brain is a roadblock for the use of stem cell therapies to treat brain diseases and injuries. Here, we report a strategy that mobilizes and guides migration of stem cells in the brain in vivo. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbe41231b2bcf959ac63645c9f97764
http://europepmc.org/articles/PMC5511115

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Fluid percussion injury device for the precise control of injury parameters

Autor: Vijayalakshmi Santhakumar, Eric J. Neuberger, Bryan J. Pfister, Radia Abdul Wahab, Bruce G. Lyeth

Publikováno v: Wahab, RA; Neuberger, EJ; Lyeth, BG; Santhakumar, V; & Pfister, BJ. (2015). Fluid percussion injury device for the precise control of injury parameters. Journal of Neuroscience Methods, 248, 16-26. doi: 10.1016/j.jneumeth.2015.03.010. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/5f17g3tg

© 2015 Elsevier B.V. Background: Injury to the brain can occur from a variety of physical insults and the degree of disability can greatly vary from person to person. It is likely that injury outcome is related to the biomechanical parameters of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e05bdce969b9b5a7c0d34717af810b8
https://doi.org/10.1016/j.jneumeth.2015.03.010

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