Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Bruce G, Allen"'
Autor:
Pramod Sahadevan, Dharmendra Dingar, Sherin A. Nawaito, Reshma S. Nair, Joëlle Trépanier, Fatiha Sahmi, Yanfen Shi, Marc‐Antoine Gillis, Martin G. Sirois, Sylvain Meloche, Jean‐Claude Tardif, Bruce G. Allen
Publikováno v:
Physiological Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)
Abstract ERK3/MAPK6 activates MAP kinase‐activated protein kinase (MK)‐5 in selected cell types. Male MK5 haplodeficient mice show reduced hypertrophy and attenuated increase in Col1a1 mRNA in response to increased cardiac afterload. In addition,
Externí odkaz:
https://doaj.org/article/dc8134f580334f129f6013b0c2a971fd
Autor:
Matthieu Ruiz, Maya Khairallah, Dharmendra Dingar, George Vaniotis, Ramzi J. Khairallah, Benjamin Lauzier, Simon Thibault, Joëlle Trépanier, Yanfen Shi, Annie Douillette, Bahira Hussein, Sherin Ali Nawaito, Pramod Sahadevan, Albert Nguyen, Fatiha Sahmi, Marc‐Antoine Gillis, Martin G. Sirois, Matthias Gaestel, William C. Stanley, Céline Fiset, Jean‐Claude Tardif, Bruce G. Allen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 4 (2021)
Background Mitogen‐activated protein kinase–activated protein kinase‐2 (MK2) is a protein serine/threonine kinase activated by p38α/β. Herein, we examine the cardiac phenotype of pan MK2‐null (MK2−/−) mice. Methods and Results Survival
Externí odkaz:
https://doaj.org/article/f621d6d646c848bc8cfc1f57645591d9
MK2 deficiency decreases mortality during the inflammatory phase after myocardial infarction in mice
Autor:
Joëlle Trépanier, Sherin A. Nawaito, Pramod Sahadevan, Fatiha Sahmi, Natacha Duquette, Danielle Gélinas, Marc-Antoine Gillis, Yanfen Shi, Cynthia Torok, Marie-Élaine Clavet-Lanthier, Gaestel Matthias, Martin G. Sirois, Jean-Claude Tardif, Bruce G. Allen
Background:Altering the onset, intensity, or duration of inflammation can impact the recovering heart’s structure and function following myocardial infarction (MI). Substrates of MAP kinase-activated protein kinase 2 (MK2) include proteins that reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8690349d288d40dc5799c5ddc6ecce
https://doi.org/10.1101/2023.03.06.531384
https://doi.org/10.1101/2023.03.06.531384
Autor:
Julie Thompson Legault, Laura Strittmatter, Jessica Tardif, Rohit Sharma, Vanessa Tremblay-Vaillancourt, Chantale Aubut, Gabrielle Boucher, Clary B. Clish, Denis Cyr, Caroline Daneault, Paula J. Waters, Azadeh Aliskashani, Bruce G. Allen, Claudine Beauchamp, Chantal Bemeur, Yan Burelle, Guy Charron, Lise Coderre, Christine Des Rosiers, Sonia Deschênes, François Labarthe, Jeannine Landry, Catherine Laprise, Geneviève Lavallée, Pierre Lavoie, Bruno Maranda, Charles Morin, Yvette Mukaneza, Tamiko Nishimura, John D. Rioux, Marie-Ève Rivard, Florin Sasarman, Eric A. Shoubridge, Nancy Tremblay, Luc Vachon, Josée Villeneuve
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 981-989 (2015)
A decline in mitochondrial respiration represents the root cause of a large number of inborn errors of metabolism. It is also associated with common age-associated diseases and the aging process. To gain insight into the systemic, biochemical consequ
Externí odkaz:
https://doaj.org/article/9a62c7ac67234db5a1b82fa740ce6d1e
Autor:
Artavazd Tadevosyan, Jiening Xiao, Sirirat Surinkaew, Patrice Naud, Clémence Merlen, Masahide Harada, Xiaoyan Qi, David Chatenet, Alain Fournier, Bruce G. Allen, Stanley Nattel
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 4 (2017)
BackgroundCardiac fibroblasts play important functional and pathophysiological roles. Intracellular (“intracrine”) angiotensin‐II (Ang‐II) signaling regulates intercellular communication, excitability, and gene expression in cardiomyocytes; h
Externí odkaz:
https://doaj.org/article/d663a4d5df9747c482bc5f5e30713103
Autor:
Grace R. Mazarura, Juliana C. C. Dallagnol, David Chatenet, Bruce G. Allen, Terence E. Hébert
Publikováno v:
American journal of physiology. Cell physiology. 323(3)
The role of different G protein-coupled receptors (GPCRs) in the cardiovascular system is well understood in cardiomyocytes and vascular smooth muscle cells (VSMCs). In the former, stimulation of Gs-coupled receptors leads to increases in contractili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e8d480dce7c424e2066dcc1bc25603
https://pubmed.ncbi.nlm.nih.gov/35938678
https://pubmed.ncbi.nlm.nih.gov/35938678
Autor:
Gérald Coulis, Avinash D. Londhe, R. Sudheer Sagabala, Yanfen Shi, David P. Labbé, Alexandre Bergeron, Pramod Sahadevan, Sherin A. Nawaito, Fatiha Sahmi, Marie Josse, Valérie Vinette, Marie-Claude Guertin, Gérard Karsenty, Michel L. Tremblay, Jean-Claude Tardif, Bruce G. Allen, Benoit Boivin
Publikováno v:
Sci Signal
Increased production of reactive oxygen species plays an essential role in the pathogenesis of several diseases, including cardiac hypertrophy. In our search to identify redox-sensitive targets that contribute to redox signaling, we found that protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a4dacdddb1530fdbcfc7f8dcf4ecf
https://doi.org/10.1126/scisignal.abn6875
https://doi.org/10.1126/scisignal.abn6875
Autor:
Angelino Calderone, Kathryn E. Hentges, Alexandre Bergeron, Rami Shukr, Bruce G. Allen, Wasay Mohiuddin Shaikh Qureshi, Louis Villeneuve, Andra Brezai
Publikováno v:
Journal of Cellular Physiology. 236:1281-1294
Cardiomyocyte migration represents a requisite event of cardiogenesis and the regenerative response of the injured adult zebrafish and neonatal rodent heart. The present study tested the hypothesis that the appearance of the intermediate filament pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d36c186fe22608bd92b0e17713578d
https://doi.org/10.1002/jcp.29934
https://doi.org/10.1002/jcp.29934
Autor:
Doa'a G.F. Al-U'datt, Carole C. Tranchant, Ahmed Al-Dwairi, Mohammad Alqudah, Othman Al-Shboul, Roddy Hiram, Bruce G. Allen, Saied Jaradat, Jenan Alqbelat, Ahmed S. Abu-zaiton
Publikováno v:
Biochemical pharmacology. 201
Cardiac diseases are the leading cause of mortality and morbidity worldwide. Mounting evidence suggests that transglutaminases (TGs), tissue TG (TG2) in particular, are involved in numerous molecular responses underlying the pathogenesis of cardiac d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313a7479e987672aaf1705f70c6ad4df
https://pubmed.ncbi.nlm.nih.gov/35617996
https://pubmed.ncbi.nlm.nih.gov/35617996