Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Bruce E. McNutt"'
1
Efficacy and safety of 30-minute infusions of conivaptan in euvolemic and hypervolemic hyponatremia
Autor: Bruce E. McNutt, Sanjay Kalra, Michael J. Koren, Sally Klasen, Anura Abeyratne, Abdullah Hamad
Publikováno v: American Journal of Health-System Pharmacy. 68:818-827
Purpose The efficacy and safety of conivaptan administered via 30-minute i.v. infusion to patients with euvolemic or hypervolemic hyponatremia were evaluated. Methods Hospitalized adults with a baseline serum sodium concentration (SSC) of 115–130 m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca5ba33accc2d47b3bad0099f72a81b
https://doi.org/10.2146/ajhp100260
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3
Effect of loading dose and formulation on safety and efficacy of conivaptan in treatment of euvolemic and hypervolemic hyponatremia
Autor: Juan Carlos Q. Velez, Bruce E. McNutt, Shai Efrati, Anura Abeyratne, Arie Oliven, Sally Klasen, John M. Arthur, Sanjay Kalra
Publikováno v: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 68(7)
Purpose The effect of loading dose and formulation on the safety and efficacy of conivaptan in the treatment of euvolemic and hypervolemic hyponatremia was studied. Methods This parallel-group study randomized 121 hospitalized patients with euvolemic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce5f98cda285861e7156e8fde841855
https://pubmed.ncbi.nlm.nih.gov/21411800
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4
Effect of caffeine on SPECT myocardial perfusion imaging during regadenoson pharmacologic stress: rationale and design of a prospective, randomized, multicenter study
Autor: Randall C. Thompson, Ami E. Iskandrian, Billy Franks, Bruce E. McNutt, Furqan H. Tejani
Publikováno v: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 18(1)
Caffeine attenuates the coronary hyperemic response to adenosine by competitive A₂(A) receptor blockade. This study aims to determine whether oral caffeine administration compromises diagnostic accuracy in patients undergoing vasodilator stress myo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7500da4e64b1e7f44bb9e569af570b3
https://pubmed.ncbi.nlm.nih.gov/21082298
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5
Pharmacokinetics of Terfenadine in Healthy Elderly Subjects
Autor: Richard A. Okerholm, Stephen J. Ruberg, Bruce E. Mcnutt, Kelly K. Antony, Barbara J. Walker, Patricia A. Westmark, Mark G. Eller
Publikováno v: The Journal of Clinical Pharmacology. 32:267-271
The pharmacokinetics of the terfenadine active metabolite, metabolite I, was examined in ten healthy elderly adults and ten younger adults after single-dose oral administration of 120-mg terfenadine. All subjects successfully completed the study with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6472e7b9b2b4570255bae0b8d97e535
https://doi.org/10.1002/j.1552-4604.1992.tb03835.x
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6
Dose-response relation between terfenadine (Seldane) and the QTc interval on the scalar electrocardiogram: distinguishing a drug effect from spontaneous variability
Autor: Joel Morganroth, Craig M. Pratt, Stuart Harris, Lemuel A. Moyé, Jeremy N. Ruskin, James K. Woodward, Stephen J. Ruberg, Bruce E. Mcnutt
Publikováno v: American heart journal. 131(3)
The primary goal of this investigation was to describe the effect of terfenadine on the QT interval corrected for heart rate (QTc) of the scalar electrocardiogram (ECG). The design was double-blind, four-period crossover, dose escalation, which invol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a46fdc3ce874613bc26ba90e01cf6c
https://pubmed.ncbi.nlm.nih.gov/8604626
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7
Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome
Autor: Paul S. Marshall, Bruce E. McNutt, Nicole Lurie, Phillip K. Peterson, Alfred M. Pheley, Paul Steinberg, Carlos H. Schenck
Publikováno v: The Journal of allergy and clinical immunology. 97(1 Pt 1)
BACKGROUND: There is no established treatment for chronic fatigue syndrome (CFS), an illness characterized by disabling fatigue exacerbated by physical activity. A variety of immunologic abnormalities have been reported, including a high incidence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526f592b59744649c9438f06fe93dcd
https://pubmed.ncbi.nlm.nih.gov/8568124
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9
Absence of food effects on the pharmacokinetics of terfenadine
Autor: Mark G. Eller, Kelly K. Antony, Bruce E. Mcnutt, Barbara J. Walker, Richard A. Okerholm, Lianng Yuh
Publikováno v: Biopharmaceuticsdrug disposition. 13(3)
Administration of terfenadine (Seldane) immediately after a high fat breakfast slightly affects the rate but not the extent of absorption relative to fasting administration. Mean peak levels of the active metabolite were increased by 13 per cent but
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e89ed6641b0af245e687c1b1f4921a
https://pubmed.ncbi.nlm.nih.gov/1576325
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