Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Bruce E. Bowler"'
Publikováno v:
Journal of the American Chemical Society. 144:21184-21195
Autor:
Taylor Van Gundy, Dhara Patel, Bruce E. Bowler, Michael T. Rothfuss, Allie J. Hall, Christopher Davies, Laura S. Hall, Dan Drecktrah, Richard T. Marconi, D. Scott Samuels, Meghan C. Lybecker
Publikováno v:
Molecular Microbiology.
Autor:
Meghan C. Lybecker, Taylor Van Gundy, Dhara Patel, Bruce E. Bowler, Michael T. Rothfuss, Allie J. Hall, Christopher Davies, Laura Hall, Dan Drecktrah, Richard T. Marconi, D Scott Samuels
PlzA is a c-di-GMP-binding protein crucial for adaptation of the Lyme disease spirochete Borrelia ( Borreliella) burgdorferi during its enzootic life cycle. Unliganded apo-PlzA is important for vertebrate infection, while liganded holo-PlzA is import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c320624871cd2a9e1afe22bce5ae0be
https://doi.org/10.22541/au.168060960.03851580/v1
https://doi.org/10.22541/au.168060960.03851580/v1
Publikováno v:
Journal of the American Chemical Society. 142:19532-19539
Cytochrome c binds cardiolipin on the concave surface of the inner mitochondrial membrane, before oxidizing the lipid and initiating the apoptotic pathway. This interaction has been studied in vitro, where mimicking the membrane curvature of the bind
Autor:
Dustin C. Becht, Moses J. Leavens, Baisen Zeng, Michael T. Rothfuss, Klára Briknarová, Bruce E. Bowler
Publikováno v:
Biochemistry
The structure of the first ubiquitin-associated domain from HHR23A, UBA(1), was determined by X-ray crystallography at 1.60 Å resolution, and its stability, folding kinetics and residual structure under denaturing conditions have been investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62928f47992598c10b4aecebb07913c
https://europepmc.org/articles/PMC9150713/
https://europepmc.org/articles/PMC9150713/
Autor:
Margaret M. Elmer-Dixon, Harmen B. Steele, James T. Rogan, Bruce E. Bowler, J.B. Alexander Ross
Publikováno v:
Biochemistry. 59:2055-2068
Oxidation of cardiolipin (CL) by cytochrome c (cytc) has been proposed to initiate the intrinsic pathway of apoptosis. Domain-swapped dimer (DSD) conformations of cytc have been reported both by our laboratory and by others. The DSD is an alternate c
Publikováno v:
Biochemistry
Rhodopseudomonas palustris cytochrome c', a four-helix bundle, and the second ubiquitin-associated domain, UBA(2), a three-helix bundle from the human homologue of yeast Rad23, HHR23A, deviate from random coil behavior under denaturing conditions in
Autor:
Mike T. Rothfuss, Dustin C. Becht, Baisen Zeng, Levi J. McClelland, Cindee Yates-Hansen, Bruce E. Bowler
Publikováno v:
Biophysical Journal. 121:48a-49a
Cardiolipin Preferentially Partitions to the Inner Leaflet of Mixed Lipid Large Unilamellar Vesicles
Publikováno v:
The Journal of Physical Chemistry B. 123:9111-9122
Cardiolipin (CL), an anionic phospholipid constituting 20% of the inner mitochondrial membrane (IMM) of eukaryotes, stabilizes electron transport chain (ETC) complexes and is a signaling agent in the early stages of apoptosis. For apoptosis, CL moves
Autor:
Haotian Lei, Bruce E. Bowler
Publikováno v:
The Journal of Physical Chemistry B. 123:8939-8953
The A51V variant of human cytochrome c is linked to thrombocytopenia 4 (THC4), a condition that causes decreased blood platelet counts. A 1.82 A structure of the A51V variant shows only minor changes in tertiary structure relative to the wild-type (W