Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Bruce E Eaton"'
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Autor:
Lisa A Michaels, Bruce E Eaton
Publikováno v:
Cell and Gene Therapy Insights. 7:851-856
Publikováno v:
Energy Environ. Sci.. 4:398-402
Biomolecules such as RNA, DNA, peptides, and proteins are emerging as powerful chemical tools for the synthesis of inorganic nanoparticles. Specific biomolecule sequences have been isolated that afford remarkable control over the size, shape, polymor
Publikováno v:
Current Opinion in Chemical Biology. 12:78-85
DNA array technology has changed all discussions about proteomics. Whole genome arrays allow unbiased experimentation, and the surprises that flow from those approaches. 'Whole proteome' proteomics is not possible today, and might never be possible u
Autor:
Thomas L. Netzel, Charles E. Kerr, C. Denise Mitchell, Bruce E. Eaton,§ and, Yun-Ming Ying,†,‡
Publikováno v:
The Journal of Physical Chemistry B. 104:2166-2175
This paper presents results of the synthesis and photophysical study of N-(1-pyrenylmethyl)-2‘-deoxyuridine-5-carboxamide (PMA-dU) and its spectroscopic model N-acetyl-1-aminomethylpyrene (PMA-Ac). The goal in these studies is to learn about the in
Publikováno v:
The Journal of Physical Chemistry B. 104:1637-1650
This paper reports results of the synthesis and photophysical study of 5-(N-carboxy-1-aminopyrenyl)-2‘-deoxyuridine (PA-dU) and its spectroscopic model N-acetyl-1-aminopyrene (PA-Ac). Absorbance and emission spectra, emission quantum yields, and em
Publikováno v:
Journal of the American Chemical Society. 122:1015-1021
A group of eight unique RNA sequences isolated from a single in vitro selection experiment were characterized based on their Diels−Alderase properties. Five of the eight isolates contain a 10-base conserved region, while the remaining three do not
Autor:
Bruce E. Eaton, Theodore M. Tarasow
Publikováno v:
Cellular and Molecular Life Sciences CMLS. 55:1463-1472
The Diels-Alder reaction provides a general and facile entry for the synthesis of six-membered cyclic structures. Consequently, it has been used extensively by organic chemists for the construction of complex compounds with pharmaceutical potential.
Publikováno v:
Journal of the American Chemical Society. 121:3614-3617
The active site components and substrate specificity of an RNA Diels−Alderase (DA22) were investigated. Diels−Alderase activity was found to be highly dependent on a unique 5-position pyridyl modified uridine. Even closely related pyridyl modific
Autor:
Theodore M. Tarasow, Bruce E. Eaton
Publikováno v:
Biopolymers. 48:29-37
In this manuscript the catalytic ability of RNA is examined and compared to other biopolymers. Despite having considerably fewer catalytically enabling properties when compared to proteins, the power of in vitro selection has allowed for RNA and DNA