Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Bruce E, Loveland"'
Autor:
Kate L. Loveland, Britta Klein, Dana Pueschl, Sivanjah Indumathy, Martin Bergmann, Bruce E. Loveland, Mark P. Hedger, Hans-Christian Schuppe
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Germline development in vivo is dependent on the environment formed by somatic cells and the differentiation cues they provide; hence, the impact of local factors is highly relevant to the production of sperm. Knowledge of how somatic and germline ce
Externí odkaz:
https://doaj.org/article/0334cca436b24472b7bc85492ca4e66b
Autor:
Mark P. Hedger, N. Da Silva, Sivanjah Indumathy, Hans-Christian Schuppe, B. Klein, Martin Bergmann, M.J. Hickey, Bruce E. Loveland, Daniela Fietz, Kate L Loveland, D. Pueschl
Publikováno v:
Journal of reproductive immunology. 142
Detailed morphological characterization of testicular leukocytes in the adult CX3CR1 gfp/+ transgenic mouse identified two distinct CX3CR1 + mononuclear phagocyte (macrophage and dendritic cell) populations: stellate/dendriform cells opposed to the s
Autor:
Shuo Li, Stefan Floess, Alf Hamann, Silvana Gaudieri, Andrew Lucas, Margaret Hellard, Stuart Roberts, Geza Paukovic, Magdalena Plebanski, Bruce E. Loveland, Campbell Aitken, Simon Barry, Louis Schofield, Eric J. Gowans
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6 (2012)
Externí odkaz:
https://doaj.org/article/1b4bf334fffa40168f3076115dbee937
Autor:
Shuo Li, Stuart Roberts, Magdalena Plebanski, Maelenn Gouillou, Tim Spelman, Philippe Latour, David Jackson, Lorena Brown, Rosemary L Sparrow, H Miles Prince, Derek Hart, Bruce E Loveland, Eric J Gowans
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e39368 (2012)
We have previously reported a world-first phase I clinical trial to treat HCV patients using monocyte-derived dendritic cells (Mo-DC) loaded with HCV-specific lipopeptides. While the brief treatment proved to be safe, it failed to reduce the viral lo
Externí odkaz:
https://doaj.org/article/fe96ac32017b46fab318fc7acca2fd55
Autor:
Shuo Li, Stefan Floess, Alf Hamann, Silvana Gaudieri, Andrew Lucas, Margaret Hellard, Stuart Roberts, Geza Paukovic, Magdalena Plebanski, Bruce E Loveland, Campbell Aitken, Simon Barry, Louis Schofield, Eric J Gowans
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000707 (2009)
We reported previously that a proportion of natural CD25(+) cells isolated from the PBMC of HCV patients can further upregulate CD25 expression in response to HCV peptide stimulation in vitro, and proposed that virus-specific regulatory T cells (Treg
Externí odkaz:
https://doaj.org/article/b647f92a4c5a4c48b814381e4af918b7
Autor:
Annemiek B van Spriel, Mariam Sofi, Kate H Gartlan, Alie van der Schaaf, Ineke Verschueren, Ruurd Torensma, Reinier A P Raymakers, Bruce E Loveland, Mihai G Netea, Gosse J Adema, Mark D Wright, Carl G Figdor
Publikováno v:
PLoS Pathogens, Vol 5, Iss 3, p e1000338 (2009)
Immunoglobulin A (IgA) secretion by plasma cells in the immune system is critical for protecting the host from environmental and microbial infections. However, the molecular mechanisms underlying the generation of IgA(+) plasma cells remain poorly un
Externí odkaz:
https://doaj.org/article/2d710e37a74e4f89a83faca68b52c341
Autor:
Kate L Loveland, Bruce E. Loveland, Mark P. Hedger, Britta Klein, Hans-Christian Schuppe, Martin Bergmann
Publikováno v:
Andrology. 5:763-770
Testicular germ cell tumours (TGCT) typically contain high numbers of infiltrating immune cells, yet the functional nature and consequences of interactions between GCNIS (germ cell neoplasia in situ) or seminoma cells and immune cells remain unknown.
Publikováno v:
Virology. 412(1):83-90
The transmembrane domains (TMDs) of dengue virus type-1 M protein (DENV-1M) were reported to form cation-selective channels in artificial lipid bilayers. We further explored this observation using the two-electrode voltage clamp (TEVC) method on the
Publikováno v:
Cellular Immunology. 272:87-93
Pim-1 is an important signaling molecule mediating cell proliferation and survival. Our previous study identified a Pim-1 specific monoclonal antibody, P9, with significant inhibitory effect on cell proliferation. Herein, we report that P9 inhibited
Publikováno v:
Experimental Hematology. 37:1284-1294
Objective Based on our previous findings that Pim-1 was expressed on the cell surface and could be targeted with a highly specific anti–Pim-1 monoclonal antibody (P9), this study aims to evaluate the possibility that Pim-1 could be targeted for the