Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Bruce D. Weintraub"'
Autor:
Armando Bartolazzi, Lajos Balogh, Isabella Manni, Michela Varani, Filippo Galli, Alberto Signore, Bruce D. Weintraub, Giuseppe Campagna, Chiara Lauri, Mariusz W. Szkudlinski, Giulia Piaggio
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 9
Journal of Clinical Medicine, Vol 10, Iss 1878, p 1878 (2021)
Volume 10
Issue 9
Journal of Clinical Medicine, Vol 10, Iss 1878, p 1878 (2021)
Differentiated thyroid cancer (DTC) cells may lose NIS expression and iodine uptake, but usually express TSH receptors (TSHR). Therefore, the aim of our study was to compare two radiolabeled superagonist TSH analogues for DTC imaging. These analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8737c50665d7ff4b3509018c1052f52c
http://hdl.handle.net/11573/1589321
http://hdl.handle.net/11573/1589321
Autor:
Samanta Taurone, Enzo Agostinelli, Giulia Piaggio, Enrica Bianchi, Marco Artico, Mariusz W. Szkudlinski, Alberto Signore, Bruce D. Weintraub, Filippo Galli, Isabella Manni, Rudi Dierckx
Publikováno v:
International journal of oncology, 50(6), 2171-2179. SPANDIDOS PUBL LTD
Angiogenesis is the main process responsible for tumor growth and metastatization. The principal effector of such mechanism is the vascular endothelial growth factor (VEGF) secreted by cancer cells and other components of tumor microenvironment. Radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ad882d764729f6dcaf2d0bc6cfbd74
https://research.rug.nl/en/publications/16f4e7d3-8f72-4e46-9885-13600d6cd300
https://research.rug.nl/en/publications/16f4e7d3-8f72-4e46-9885-13600d6cd300
Autor:
Bruce D. Weintraub, Torsten Kuwert, Martin G. Pomper, Valerie Fremont, Mariusz W. Szkudlinski, Simone Maschauer, Vladimir Wolf, Catherine A. Foss, Sridhar Nimmagadda, Olaf Prante, Julia Reinfelder
Publikováno v:
Thyroid. 21:783-792
Superagonist analogs of human thyroid-stimulating hormone (hTSH) may stimulate the uptake of (131)I-iodide and (18)F-fluorodeoxyglucose ((18)F-FDG) in thyroid carcinomas to a greater degree than hTSH. We herein report the potency and efficacy of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe15d41a7d040381a1df3b5e241de498
https://doi.org/10.1089/thy.2010.0394
https://doi.org/10.1089/thy.2010.0394
Autor:
Julia Reinfelder, Robert Stoehr, Valerie Fremont, Simone Maschauer, Mariusz W. Szkudlinski, Olaf Prante, Bruce D. Weintraub, Arndt Hartmann, Torsten Kuwert
Publikováno v:
Journal of Nuclear Medicine. 50:1364-1370
Dedifferentiation of thyroid carcinoma is accompanied by increased accumulation of the PET tracer (18)F-FDG. The molecular mechanisms responsible for this phenomenon are poorly understood. Therefore, we studied the regulation of (18)F-FDG uptake by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7f0b8ea26ff8fa15b3c1c5b5adce6d
https://doi.org/10.2967/jnumed.109.062331
https://doi.org/10.2967/jnumed.109.062331
Autor:
Markus Luster, Martin Schlumberger, Furio Pacini, Steven I. Sherman, Kathryn G. Schuff, Ernest L. Mazzaferri, Christoph Reiners, Mary H. Samuels, Gilbert H. Daniels, Monica C. Skarulis, Bryan R. Haugen, Paul W. Ladenson, David S. Cooper, E. Chester Ridgway, Pamela R. Schroeder, Bruce D. Weintraub, Lewis E. Braverman, Douglas S. Ross, Terry F. Davies
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 91:878-884
Context: Thyroid carcinoma requires lifelong monitoring with serum thyroglobulin, radioactive iodine whole body scanning, and other imaging modalities. Levothyroxine (l-T4) withdrawal for thyroglobulin measurement and whole body scanning increases th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8fcd199be1bc403541b3cae311259d
https://doi.org/10.1210/jc.2005-2064
https://doi.org/10.1210/jc.2005-2064
Autor:
Bruce D. Weintraub, Alberto Signore, Filippo Galli, Valerie Fremont, Mariusz W. Szkudlinski, Lajos Balogh, Giulia Piaggio, Rudi Dierckx, Isabella Manni
Publikováno v:
Thyroid, 24(8), 1297-1308. MARY ANN LIEBERT, INC
Background: Differentiated thyroid carcinomas originating from thyroid follicular cells are frequent tumors of the thyroid with relatively good prognosis due to improved surgical techniques and follow-up procedures. Poorly differentiated thyroid canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f12ceaddcedc3b8e568b128941e795
http://hdl.handle.net/11573/652057
http://hdl.handle.net/11573/652057
Autor:
Bruce D. Weintraub, Kim Phuong, T. Tong, Mathis Grossmann, Holger Leitolf, Mariusz W. Szkudlinski
Publikováno v:
Journal of Biological Chemistry. 275:27457-27465
We have previously engineered the first superactive analogs of human thyrotropin (hTSH) by using a novel design strategy. In this study, we have applied homology comparisons focusing on the aL3 loop of the common a-subunit of human glycoprotein hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69106b3fec7cfe051cc3733d4ca802ec
https://doi.org/10.1016/s0021-9258(19)61530-9
https://doi.org/10.1016/s0021-9258(19)61530-9
Autor:
Bruce D. Weintraub, David Puett, Perma Narayan, Kim Phuong T. Tong, Valerie Fremont, Judy Chen, Meng Zhang, Mariusz W. Szkudlinski
Publikováno v:
Endocrinology. 141:3514-3517
Among glycoprotein hormone receptors the TSH receptor (TSHR) is the most susceptible to constitutive activation by mutations in various regions of the molecule, including mutations in the extracellular domain (ECD) and extracellular loops of the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da7365c704c24e4f9d46c49f825c1ae
https://doi.org/10.1210/endo.141.9.7790
https://doi.org/10.1210/endo.141.9.7790
Publikováno v:
Methods. 21:67-81
This article provides the reader with an overview of methodological strategies to investigate structure-function relationships of human thyroid-stimulating hormone (hTSH). Various aspects of hTSH production, purification, and characterization describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1302bc89e8155a86ecad7753929029
https://doi.org/10.1006/meth.2000.0976
https://doi.org/10.1006/meth.2000.0976
Autor:
David S. Cooper, Harry R. Maxon, Kevin McEllin, Martin Schlumberger, Carole A. Spencer, Ralph R. Cavalieri, Christoph Reiners, Monica C. Skarulis, Kathryn E. Graham, Gilbert H. Daniels, Bryan R. Haugen, Furio Pacini, Steven I. Sherman, Ernest L. Mazzaferri, Paul W. Ladenson, Terry F. Davies, Mary H. Samuels, Leslie J. DeGroot, Markus Luster, Lewis E. Braverman, David V. Becker, E. Chester Ridgway, Bruce D. Weintraub, Douglas S. Ross
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:3877-3885
Recombinant human TSH has been developed to facilitate monitoring for thyroid carcinoma recurrence or persistence without the attendant morbidity of hypothyroidism seen after thyroid hormone withdrawal. The objectives of this study were to compare th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55446f0f0d30664aafb11942443ba007
https://doi.org/10.1210/jcem.84.11.6094
https://doi.org/10.1210/jcem.84.11.6094