Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Bruce D. Hilton"'
Publikováno v:
Journal of Heterocyclic Chemistry. 50:281-287
High resolution MS, 1D, and 2D NMR were used to determine the structure of a unique cationic impurity generated during the synthesis of Preladenant™ H/D exchange experiments were performed by both MS and NMR to confirm the acidic nature of the cati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590860b0198c5be2e118a3560143b00f
https://doi.org/10.1002/jhet.1027
https://doi.org/10.1002/jhet.1027
Autor:
Xiaoyong Fu, Bruce D. Hilton, Kiran Muppalla, Jiong Yang, Weidong Tong, Wendy Zhong, Jianguo Yin, Gary E. Martin
Publikováno v:
Journal of Heterocyclic Chemistry. 49:1163-1168
A highly colored impurity formed at low levels during the preparation of 3-amino N,N-dimethyl salicylamide was isolated and identified as 2-amino-N,N,N′,N′-tetramethyl-3-oxo-3H-phenoxazin-4,6-dicarboxamide using mass spectrometry and two-dimensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fc88e08f46ae329d19d3e9a5002cbd
https://doi.org/10.1002/jhet.981
https://doi.org/10.1002/jhet.981
Autor:
Bruce D. Hilton, Gary E. Martin
Publikováno v:
Journal of Heterocyclic Chemistry. 49:526-532
Considerable work has been invested in the area of computer-assisted structure elucidation (CASE) methods. As NMR techniques have been developed that provide more effective atom-to-atom connectivity information, it has become theoretically possible t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07f53dae0277bd99fe08f70454c8992
https://doi.org/10.1002/jhet.803
https://doi.org/10.1002/jhet.803
Publikováno v:
Magnetic Resonance in Chemistry. 49:641-647
Long-range, two-dimensional heteronuclear shift correlation NMR methods play a pivotal role in the assembly of novel molecular structures. The well-established GHMBC method is a high-sensitivity mainstay technique, affording connectivity information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaebb7dac0c3673b08b2eb84b20539a6
https://doi.org/10.1002/mrc.2793
https://doi.org/10.1002/mrc.2793
Publikováno v:
Journal of Heterocyclic Chemistry. 48:948-951
The structurally complex antifungal agent posaconazole has been well characterized by conventional 1H- and 13C-NMR studies. In contrast, 15N resonance assignments have never been reported. We now wish to report the assignment of the eight 15N resonan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338e2762bb0c33cceea641bd59e311a2
https://doi.org/10.1002/jhet.665
https://doi.org/10.1002/jhet.665
Publikováno v:
Magnetic Resonance in Chemistry. 49:350-357
Utilizing 13C-13C connectivity networks for the assembly of carbon skeletons from HSQC-ADEQUATE spectra was recently reported. HSQC-ADEQUATE data retain the resonance multiplicity information of the multiplicity-edited GHSQC spectrum and afford a sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d4322b3b042f7d5b2f9eef97fdc2212
https://doi.org/10.1002/mrc.2757
https://doi.org/10.1002/mrc.2757
Publikováno v:
Magnetic Resonance in Chemistry. 49:248-252
Various experimental methods have been developed to unequivocally identify vicinal neighbor carbon atoms. Variants of the HMBC experiment intended for this purpose have included 2J3J-HMBC and H2BC. The 1,1-ADEQUATE experiment, in contrast, was develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc3b65e6c24b1637b9e139f57d40cdf
https://doi.org/10.1002/mrc.2743
https://doi.org/10.1002/mrc.2743
Publikováno v:
Magnetic Resonance in Chemistry. 46:997-1002
Long-range homonuclear coupling pathways can be observed in COSY or GCOSY spectra by the acquisition of spectra with larger numbers of increments of the evolution period, t1, than would normally be used. Alternatively, covariance processing of COSY-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f4641099990b146ba2e3e051fd54b52
https://doi.org/10.1002/mrc.2260
https://doi.org/10.1002/mrc.2260
Publikováno v:
Journal of Heterocyclic Chemistry. 45:1109-1113
Recent reports have demonstrated the unsymmetrical indirect covariance combination of discretely acquired 2D NMR experiments into spectra that provide an alternative means of accessing the information content of these spectra. The method can be thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a969318385eb1b2d3646397a845a5ccd
https://doi.org/10.1002/jhet.5570450426
https://doi.org/10.1002/jhet.5570450426
Publikováno v:
Magnetic Resonance in Chemistry. 46:138-143
Several groups of authors have reported studies in the areas of indirect and unsymmetrical indirect covariance NMR processing methods. Efforts have recently focused on the use of unsymmetrical indirect covariance processing methods to combine various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fbefc523612e4ea5c73f6ec4a086d6
https://doi.org/10.1002/mrc.2141
https://doi.org/10.1002/mrc.2141