Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Bruce D. Freedman"'
Autor:
Ziying Han, Michael P. Schwoerer, Philip Hicks, Jingjing Liang, Gordon Ruthel, Corbett T. Berry, Bruce D. Freedman, Cari A. Sagum, Mark T. Bedford, Sachdev S. Sidhu, Marius Sudol, Ronald N. Harty
Publikováno v:
Diseases, Vol 6, Iss 3, p 64 (2018)
Lassa fever virus (LFV) belongs to the Arenaviridae family and can cause acute hemorrhagic fever in humans. The LFV Z protein plays a central role in virion assembly and egress, such that independent expression of LFV Z leads to the production of vir
Externí odkaz:
https://doaj.org/article/22b99517ea814842b01368e5cb38d09b
Autor:
Ziying Han, Shantoshini Dash, Cari A Sagum, Gordon Ruthel, Chaitanya K Jaladanki, Corbett T Berry, Michael P Schwoerer, Nina M Harty, Bruce D Freedman, Mark T Bedford, Hao Fan, Sachdev S Sidhu, Marius Sudol, Olena Shtanko, Ronald N Harty
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008231 (2020)
Ebola (EBOV) and Marburg (MARV) are members of the Filoviridae family, which continue to emerge and cause sporadic outbreaks of hemorrhagic fever with high mortality rates. Filoviruses utilize their VP40 matrix protein to drive virion assembly and bu
Externí odkaz:
https://doaj.org/article/2b5a06ea5c4348918068392abc239b3c
Autor:
Xianxin Hua, Donita C. Brady, Bruce D. Freedman, Xin He, Yuan Wu, Haoren Wang, Yuanyuan Liu, Smita Matkar, Katherine M. Szigety, Corbett T. Berry, Jian Ma, Caroline I. Davis, Zijie Feng, Kayla E. Paulosky, Rebecca A. Glynn, Bryson W. Katona
Supplemental Figure S1: Menin inhibition has minimal effects on cell growth in colon cancer cells. Supplemental Figure S2: Inhibition of menin selectively sensitizes colon cancer cells to iEGFRs. Supplemental Figure S3: BAPTA rescues cells from the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3072f660a95a321900944e5705d8be
https://doi.org/10.1158/0008-5472.22423937
https://doi.org/10.1158/0008-5472.22423937
Autor:
Xianxin Hua, Donita C. Brady, Bruce D. Freedman, Xin He, Yuan Wu, Haoren Wang, Yuanyuan Liu, Smita Matkar, Katherine M. Szigety, Corbett T. Berry, Jian Ma, Caroline I. Davis, Zijie Feng, Kayla E. Paulosky, Rebecca A. Glynn, Bryson W. Katona
Menin is a nuclear epigenetic regulator that can both promote and suppress tumor growth in a highly tissue-specific manner. The role of menin in colorectal cancer, however, remains unclear. Here, we demonstrate that menin was overexpressed in colorec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::befa6fcba17e107346b518a675e30375
https://doi.org/10.1158/0008-5472.c.6511616.v1
https://doi.org/10.1158/0008-5472.c.6511616.v1
Autor:
Xianxin Hua, Donita C. Brady, Bruce D. Freedman, Xin He, Yuan Wu, Haoren Wang, Yuanyuan Liu, Smita Matkar, Katherine M. Szigety, Corbett T. Berry, Jian Ma, Caroline I. Davis, Zijie Feng, Kayla E. Paulosky, Rebecca A. Glynn, Bryson W. Katona
This supplementary file contains methods for menin immunohistochemistry, reagents, cell culture, proliferation assays, western blotting, plasmids and transfections, RT-PCR, cell visualization assays including clonogenicity, H&E staining, and live cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69406dd38f4c362bc67af155c6d392cf
https://doi.org/10.1158/0008-5472.22423934
https://doi.org/10.1158/0008-5472.22423934
Autor:
Swarna Bais, Abigail Norwillo, Gordon Ruthel, De’Broski R. Herbert, Bruce D. Freedman, Robert M. Greenberg
Publikováno v:
Biochimie
Schistosomiasis is a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma. Mono-therapeutic treatment of this disease with the drug praziquantel, presents challenges such as inactivity against immature worms and inability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd09cdb3ca26aca9ea2e32092a6aa103
https://doi.org/10.1016/j.biochi.2021.12.018
https://doi.org/10.1016/j.biochi.2021.12.018
Publikováno v:
Cell Calcium. 113:102758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082d7f5dafc67bd1558e52f00dea9745
https://doi.org/10.1016/j.ceca.2023.102758
https://doi.org/10.1016/j.ceca.2023.102758
Publikováno v:
J Virol
Ebola virus (EBOV) and Marburg virus (MARV) continue to emerge and cause severe hemorrhagic disease in humans. A comprehensive understanding of the filovirus-host interplay will be crucial for identifying and developing antiviral strategies. The filo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0eb9a7f1fc6a0be64b069e186e2c4d
https://europepmc.org/articles/PMC8941927/
https://europepmc.org/articles/PMC8941927/
Autor:
Gordon Ruthel, Olena Shtanko, Bruce D. Freedman, Shantoshini Dash, Corbett T. Berry, Ronald N. Harty, Ziying Han
Publikováno v:
J Biol Chem
The Ebola virus (EBOV) VP40 matrix protein (eVP40) orchestrates assembly and budding of virions in part by hijacking select WW-domain–bearing host proteins via its PPxY late (L)-domain motif. Angiomotin (Amot) is a multifunctional PPxY-containing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a88cb4185d1ac5331c5f90897753df4
https://doi.org/10.1074/jbc.ac120.013171
https://doi.org/10.1074/jbc.ac120.013171
Ebola (EBOV) and Marburg (MARV) viruses continue to emerge and cause severe hemorrhagic disease in humans. A comprehensive understanding of the filovirus-host interplay will be crucial for identifying and developing antiviral strategies. The filovira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70f06a38cb7b74a19e2abae28d270305
https://doi.org/10.1101/2021.11.19.469355
https://doi.org/10.1101/2021.11.19.469355