Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bruce Cameron Hamper"'
Autor:
Deborah Aileen Mischke, Daniel M. Walker, Robert C. Chott, Kevin D. Jerome, Gopi Yalamanchili, Bruce Cameron Hamper
Publikováno v:
Biotechnology and Bioengineering. 71:28-37
Using a combination of solid phase synthesis for the preparation of N-substituted-N-acylglycines 7 followed by solution-phase ring transformation of trifluoromethylacyl munchnone intermediate 8, a library of 200 trisubstituted-5-trifluoromethylketo (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e221a08964e25f476e57c2c71fa8438b
https://doi.org/10.1002/(sici)1097-0290(200024)71:1<28::aid-bit5>3.0.co
https://doi.org/10.1002/(sici)1097-0290(200024)71:1<28::aid-bit5>3.0.co
Publikováno v:
Tetrahedron Letters. 40:4973-4976
Malonic acid resin 1 and the corresponding diester 2 have been used for the preparation of dihydropyrimidinones 6 and pyrimidinone carboxylic acids 8. Knoevenagel condensation of the unsymmetrical resin bound malonate diester 2 followed by condensati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae68ee702d86d78b7f5525ec421280f6
https://doi.org/10.1016/s0040-4039(99)00961-2
https://doi.org/10.1016/s0040-4039(99)00961-2
Autor:
Thomas J. Owen, Dennis C. Owsley, and Allen S. Kesselring, Bruce Cameron Hamper, David M. Snyderman, Robert C. Chott, Angela M. Scates
Publikováno v:
Journal of Combinatorial Chemistry. 1:140-150
A solid phase organic synthesis method has been developed for the preparation of substituted methylene malonamic acids and malonic ester mono acids 5. Two substituents are introduced into the core molecule 5 by preparation of unsymmetrical malonic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed35eedf83083387f000408817b37c1
https://doi.org/10.1021/cc9800172
https://doi.org/10.1021/cc9800172
Publikováno v:
Tetrahedron Letters. 39:2047-2050
The solid phase synthesis of unsymmetrical substituted methylene malonamic acids 7 and methylene malonic ester mono acids 8 is reported. Resin-bound malonic acid 3 is obtained by treatment of Wang's resin with Meldrum's acid. The free carboxylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f078d938b8055153c26d629ee949d187
https://doi.org/10.1016/s0040-4039(98)00184-1
https://doi.org/10.1016/s0040-4039(98)00184-1
Autor:
Ronald G. Smith, Bruce Cameron Hamper, Stephen A. Kolodziej, Angela M. Scates, Enriqueta Cortez
Publikováno v:
The Journal of Organic Chemistry. 63:708-718
A solid-phase organic synthesis method has been developed for the preparation of N-substituted-beta-aminopropionic acid oligomers or beta-peptoids 1. Treatment of polymer-bound 4-(benzyloxy)benzyl acrylate 2 with primary amines afforded N-substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13552b4276be27632c4ebc43f9116990
https://doi.org/10.1021/jo971675w
https://doi.org/10.1021/jo971675w
Publikováno v:
Tetrahedron Letters. 37:5277-5280
A series of 1,3-disubstituted-5,6-dihydropyrimidine-2,4-diones 1 are prepared by solid phase organic chemistry using a cyclization-cleavage strategy from readily available amines and isocyanates. An acrylate ester of Wangs resin is treated with prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc721c4e7f61f81e4a6f8c6c2a80c012
https://doi.org/10.1016/0040-4039(96)01103-3
https://doi.org/10.1016/0040-4039(96)01103-3
Publikováno v:
Tetrahedron Letters. 37:3671-3674
Preparation of highly substituted pyrrolidines (proline analogs) was achieved by solid-phase organic synthesis using a three component 1,3-dipolar cycloaddition of a resin bound azomethine ylide. The synthesis utilizes a series of hydroxybenzaldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe0740d3e39bfa1a69f191c3468295c7
https://doi.org/10.1016/0040-4039(96)00659-4
https://doi.org/10.1016/0040-4039(96)00659-4
Publikováno v:
Journal of Chromatography A. 666:479-484
Chiral pyrazole phenyl ethers (PPE) are highly active herbicides which are resolved by direct high-performance liquid chromatography on commercially available chiral stationary phases derived from N-3,5-dinitrobenzoyl derivatives of α-amino acids or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc570808b716a90d8558872ef7bbf582
https://doi.org/10.1016/0021-9673(94)80409-5
https://doi.org/10.1016/0021-9673(94)80409-5
Autor:
Angela S. Scates, Bruce Cameron Hamper, Thomas J. Owen, Robert C. Chott, Kevin D. Jerome, Stephen A. Kolodziej, Allen S. Kesselring
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a309f004c78eaa91f51d3b6bfb378507
https://doi.org/10.1002/chin.200128278
https://doi.org/10.1002/chin.200128278
Autor:
Bruce Cameron Hamper
Publikováno v:
Journal of Fluorine Chemistry. 48:123-131
A regioselective route to 1-methyl-3-hydroxy-5-perfluoroalkyl(1H,3H)pyrazoles has been developed. Treatment of perfluoroalkylacetylenic esters with methylhydrazine in methanol-water at 0° or in methylene chloride at low temperature leads to 1-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a4ac87bcf473c4b8dfa252d1d34d82
https://doi.org/10.1016/s0022-1139(00)82607-x
https://doi.org/10.1016/s0022-1139(00)82607-x