Výsledky vyhledávání - "Bruce Alan Beutler"

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

Autor: Ben A. Croker, Brian R. Lawson, Sophie Rutschmann, Michael Berger, Celine Eidenschenk, Amanda L. Blasius, Eva Marie Y. Moresco, Sosathya Sovath, Louise Cengia, Leonard D. Shultz, Argyrios N. Theofilopoulos, Sven Pettersson, Bruce Alan Beutler

Publikováno v: Proceedings of the National Academy of Sciences. 105:15028-15033

A recessive phenotype calledspin(spontaneous inflammation) was induced byN-ethyl-N-nitrosourea (ENU) mutagenesis in C57BL/6J mice. Homozygotes display chronic inflammatory lesions affecting the feet, salivary glands and lungs, and antichromatin antib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e7ac0c9343c0aa09253b8cbcaf94d0
https://doi.org/10.1073/pnas.0806619105

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Identification and structural and functional analysis of candidate genes on chromosome 4 in SHR that may influence essential hypertension

Autor: Samantha Kuwada Teixeira

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

O emprego de \"Total Genome Scan\" em modelos genéticos de doenças complexas tem sido fundamental para seleção de regiões cromossômicas envolvidas com traços complexos. Em nosso laboratório, identificamos cinco regiões cromossômicas associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c359154da23313f788469a392cc6aa61

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