Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Bruce A. Scoggins"'
Autor:
David G. Parkes, John P. Coghlan, Elizabeth A. Cooper, Merrindal Routley, John G. McDougall, Bruce A. Scoggins
Publikováno v:
American Journal of Hypertension. 7:905-912
Publikováno v:
American Journal of Hypertension. 3:775-781
This study investigated the ability of two diuretics, amiloride and frusemide, to prevent the development of ACTH induced hypertension in conscious sheep. Infusion of amiloride (20 mg/day) or frusemide (50 mg/day) for three days into normotensive she
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 17:377-380
1. Studies in the rat and the dog have shown that infusion of aldosterone for several weeks into the cerebral ventricles (ICV) can produce hypertension at doses that do not have an effect when infused systemically. We have previously shown that a hig
Publikováno v:
Life sciences. 57(6)
Increased arterial blood pressure following a pyrogenic reaction has been reported in previous studies, however the mechanism of this hypertension has not been examined in detail. The present study investigated the effects of both intravenous (IV) an
Autor:
John G. McDougall, William Farrugia, Janette J. Tresham, Stella O'Connell, John D. Wark, Carolyn L. Fortune, Bruce A. Scoggins
Publikováno v:
Calcified tissue international. 53(2)
Glucocorticoids adversely affect bone and mineral metabolism through a number of mechanisms, including inhibition of bone formation. Deflazacort is a glucocorticoid which has been reported to be relatively "bone-sparing." We compared the effects in o
Publikováno v:
Life sciences. 50(24)
The renal and cardiovascular effects of ANF infusion have been examined in separate series of experiments; in conscious instrumented sheep following either hemorrhage (10 mL/kg body weight) or removal of 500 mL of plasma by ultrafiltration. Renal art
Publikováno v:
Clinical and experimental hypertension. Part A, Theory and practice. 14(5)
Synthetic sex steroid administration is a major cause of iatrogenic hypertension but little is known of the haemodynamic or metabolic consequences of these steroids. This study examined the short term blood pressure, volume and metabolic consequences
Publikováno v:
American journal of hypertension. 4(8)
The hemodynamic responses to bolus injection of endothelin I (ET) at 5, 15, and 50 micrograms were examined in conscious sheep (n = 5) before and after infusion of nisoldipine at 25 micrograms/kg/h. Endothelin produced dose-dependent increases in mea
Publikováno v:
Journal of hypertension. 8(11)
Hypertension and nephrotoxicity are major clinical problems associated with cyclosporine A administration. Sheep rapidly develop hypertension after intravenous administration of cyclosporine A at 6 mg/kg per day over 5 days, and this is associated wi
Publikováno v:
American journal of hypertension. 3(11)
The present study examined the hemodynamic actions of a non-guanylate cyclase linked or "clearance" atrial natriuretic factor (ANF) receptor ligand--des[Gln116Ser117Gly118Leu119Gly120] ANF 102-121 (C-ANF 4-23)--in conscious sheep. The effect of this