Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bruce A. Prins"'
Autor:
Elmar W. J. Weiler, Farhad Khalil-Manesh, Harvey C. Gonick, Bruce A. Prins, Dilip K. Sensharma, Ralph E. Purdy
Publikováno v:
American Journal of Hypertension. 12:364-373
It has been demonstrated that human plasma contains a low molecular weight sodium-potassium–stimulated adenosine triphosphatase (Na-K-ATPase) inhibitor, which can be dissociated from a circulating protein with a molecular weight of approximately 12
Autor:
Ellis R. Levin, Gerben J. Schaaf, Joseph J. Bahl, Bruce A. Prins, Wei-Hsi Chen, Ping H. Wang, James Feng
Publikováno v:
Biochemical and Biophysical Research Communications. 245:912-917
The aim of this study was to investigate whether IGF I induction of p53 expression and p21 promoter require activation of MAP kinase in cardiac muscle cells. Compared to cardiomyocytes transfected with control vector, activation of MAP kinase by IGF
Publikováno v:
Journal of Clinical Investigation. 95:1151-1157
C-type natriuretic peptide (CNP) is a member of the natriuretic peptide family which is produced in vascular endothelial cells and may play an important paracrine role in the vasaculature. We sought to determine the regulation ofCNP production by oth
Autor:
Harrison J.L. Frank, Ellis R. Levin, Ren-Ming Hu, Ali Pedram, B. Nazario, Bruce A. Prins, Michael A. Weber
Publikováno v:
Journal of Biological Chemistry. 269:11938-11944
Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor yet identified. This peptide plays an important role in the regulation of arterial tone, in part through its interaction with endogenous vasodilator compounds. To understand the intera
Autor:
Mei-Yu Chuang, Ali Pedram, Moti L. Kashyap, Harrison J.L. Frank, Ellis R. Levin, Bruce A. Prins, Ren-Ming Hu
Publikováno v:
Journal of Clinical Investigation. 93:1056-1062
The concentration of HDL in the blood inversely correlates with the incidence of cardiovascular disease, probably related to the ability of these lipoproteins to efflux cholesterol from vascular cells. it is also possible that HDL affect the producti
Publikováno v:
The American Journal of the Medical Sciences. 307:27-35
It has been demonstrated that expansion of extracellular fluid volume induces the release of a low-molecular-weight natriuretic and sodium-potassium-activated adenosine triphosphatase inhibiting hormone (NKAI). In this study, we used a highly purifie
Autor:
Harvey C. Gonick, Bruce A. Prins, Michael A. Weber, Farhad Khalil-Manesh, Elmar W. J. Weiler, Ralph E. Purdy
Publikováno v:
American Journal of Hypertension. 6:723-729
The results of this study confirm that low lead (0.01%) but not high lead (0.5%) administration results in increased blood pressure in rats treated for up to 12 months. This effect appeared to be related to an imbalance of endothelially-derived vasoc
Autor:
Frederic A. Wyle, Bruce A. Prins, Trang Nguyen, Alberta Warner, Dan Liang, Matthew J. Domek, Peter Netzer
Publikováno v:
Helicobacter. 6(2)
Background. The pathway by which Helicobacter pylori induces apoptosis in gastric epithelial cells is not known. The aim of this study was to determine whether H. pylori-induced apoptosis is associated with SAPK/JNK activity in human gastric cancer K
Autor:
Ralph E. Purdy, Elmar W. J. Weiler, L F Saldanha, H C Gonick, F Khalil-Manesh, Bruce A. Prins
Publikováno v:
Journal of the American Society of Nephrology : JASN. 7(3)
Inhibitors of sodium-potassium-activated adenosine triphosphatase (Na-K-ATPase) have been implicated in the pathogenesis of hypertension. In the study presented here, an attempt was made to determine whether differences in the plasma levels and the r
Autor:
Bruce A. Prins, Michael A. Weber, Elmar W. J. Weiler, Farhad Khalil-Manesh, Qing Ren, Ralph E. Purdy, Harvey C. Gonick
Publikováno v:
Environmental research. 65(1)
An elevation in mean blood pressure was found in rats treated with low lead (0.01%) for 6 months and then only water for an additional 6 months (discontinuous low lead). No change in blood pressure was found in rats similarly treated with high lead (