Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Bruce A. Conway"'
Autor:
Christian M. Chilan, Bruce A. Conway
Publikováno v:
Journal of Guidance, Control, and Dynamics. 43:30-38
The optimal control of nonlinear systems is traditionally obtained by the application of the Pontryagin minimum principle. Despite the success of this methodology in finding the optimal control for...
Publikováno v:
Journal of Guidance, Control, and Dynamics. 41:1700-1714
Bounded-impulse trajectory models are an important component of many spacecraft trajectory preliminary design workflows. This paper includes discussions on practical implementation considerations f...
Publikováno v:
J Guid Control Dyn
Many optimization methods require accurate partial derivative information in order to ensure efficient, robust, and accurate convergence. In this paper, analytic methods are developed for computing complex partial derivatives of two bounded-impulse t
Autor:
Bruce A. Conway, Mauro Pontani
Publikováno v:
Journal of Guidance, Control, and Dynamics. 41:360-376
Earth–Mars cycling spacecraft have been proposed as potentially beneficial to Mars exploration. There are many types of cyclers, but their common characteristic is that they have a heliocentric tra...
Autor:
Piotr L. Sklepkiewicz, Czestkowski Wojciech J, Bruce R. Conway, Ryan Sheeler, Tom Noonan, Alexandra Cousido-Siah, Alberto Podjarny, Sylwia Olejniczak, Agnieszka Zagozdzon, Jacek Olczak, Anna Jedrzejczak, Andre Mitschler, Adam Golebiowski, Paul Beckett, Firas Fadel, Karolina Dzwonek, Marzena Mazur, William M. Hungerford, Barbara Dymek, Robert Koralewski, Jakub Golab, Keyvan Mahboubi
Publikováno v:
Journal of Medicinal Chemistry
This article highlights our work toward the identification of a potent, selective, and efficacious acidic mammalian chitinase (AMCase) inhibitor. Rational design, guided by X-ray analysis of several inhibitors bound to human chitotriosidase (hCHIT1),
Spatial statistical point prediction guidance for heating-rate-limited aeroassisted orbital transfer
Autor:
Pradipto Ghosh, Bruce A. Conway
Publikováno v:
Acta Astronautica. 111:257-269
Feedback control of constrained non-linear dynamical systems satisfying a certain optimality criterion and meeting a specified transfer objective in the state space is recognized as one of the most challenging problems in control theory. One approach
Autor:
Christian M. Chilan, Bruce A. Conway
Publikováno v:
Journal of Optimization Theory and Applications. 167:161-194
Few sophisticated problems in the optimal control of a dynamical system can be solved analytically. There are many numerical solution methods, but most, especially those with the most potential accuracy, work iteratively and must be initialized with
Autor:
Minkoo Ji, Alberto Podjarny, Yung Lee, M. Andreoli, Erik Jagdmann, Bruce R. Conway, Ryan Sheeler, Darren Whitehouse, Czestkowski Wojciech J, Adam Golebiowski, Jacek Olczak, Andre Mitschler, Alexandra Cousido-Siah, Wieslawa Piotrowska, Todd Robert Ryder, Marzena Mazur, Michael C. Van Zandt, F.X. Ruiz, Paul Beckett, Hagen Schroeter
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4837-4841
The Ugi reaction has been successfully applied to the synthesis of novel arginase inhibitors. In an effort to decrease conformational flexibility of the previously reported series of 2-amino-6-boronohexanoic acid (ABH) analogs 1, we designed and synt
Autor:
Bruce A. Conway, Christian M. Chilan
Publikováno v:
Journal of Guidance, Control, and Dynamics. 36:1410-1424
A modern space mission is assembled from multiple phases or events such as impulsive maneuvers, coast arcs, thrust arcs, and planetary flybys. Traditionally, a mission planner would resort to intuition and experience to develop a sequence of events f