Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Bruce A Vallance"'
Autor:
Franziska A Graef, Larissa S Celiberto, Joannie M Allaire, Mimi T Y Kuan, Else S Bosman, Shauna M Crowley, Hyungjun Yang, Justin H Chan, Martin Stahl, Hongbing Yu, Candice Quin, Deanna L Gibson, Elena F Verdu, Kevan Jacobson, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
Reducing food intake is a common host response to infection, yet it remains unclear whether fasting is detrimental or beneficial to an infected host. Despite the gastrointestinal tract being the primary site of nutrient uptake and a common route for
Externí odkaz:
https://doaj.org/article/0e0ea62074644ca3b0f075eb8663545f
Autor:
Naveen Parmar, Kyle Burrows, Pia M Vornewald, Håvard T Lindholm, Rosalie T Zwiggelaar, Alberto Díez-Sánchez, Mara Martín-Alonso, Madeleine Fosslie, Bruce A Vallance, John Arne Dahl, Colby Zaph, Menno J Oudhoff
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009476 (2021)
Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and immunity and can be therapeu
Externí odkaz:
https://doaj.org/article/6a34613768804c59bee0718fbb1e24ef
Autor:
Gregory A Taylor, Hsin-I Huang, Brian E Fee, Nourhan Youssef, Mark L Jewell, Viviana Cantillana, Alexi A Schoenborn, Allison R Rogala, Anne F Buckley, Carl G Feng, Bruce A Vallance, Ajay S Gulati, Gianna E Hammer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that def
Externí odkaz:
https://doaj.org/article/0f551c4084a24ce09013efa7ff036e98
Autor:
Shauna M Crowley, Xiao Han, Joannie M Allaire, Martin Stahl, Isabella Rauch, Leigh A Knodler, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008498 (2020)
We investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium infection of murine intestinal epithelial cells (IECs). Salmonella burdens were significantly greater in the intestines of caspase
Externí odkaz:
https://doaj.org/article/038531766fc4486bbc499e93c5ab38da
Autor:
Xue Xia, Yue Liu, Andrea Hodgson, Dongqing Xu, Wenxuan Guo, Hongbing Yu, Weifeng She, Chenxing Zhou, Lei Lan, Kai Fu, Bruce A Vallance, Fengyi Wan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007898 (2019)
Attaching/Effacing (A/E) bacteria include human pathogens enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC), and their murine equivalent Citrobacter rodentium (CR), of which EPEC and EHEC are important causative agents of foo
Externí odkaz:
https://doaj.org/article/3998c08814ba41c4afc823c4cc8e2e8f
Autor:
Anna Manko, Jean-Paul Motta, James A Cotton, Troy Feener, Ayodele Oyeyemi, Bruce A Vallance, John L Wallace, Andre G Buret
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178647 (2017)
Our understanding of polymicrobial gastrointestinal infections and their effects on host biology remains incompletely understood. Giardia duodenalis is an ubiquitous intestinal protozoan parasite infecting animals and humans. Concomitant infections w
Externí odkaz:
https://doaj.org/article/06c51602b1ba4a22b662dda0b4f117a9
Autor:
Kshipra Singh, Nicole T Al-Greene, Thomas G Verriere, Lori A Coburn, Mohammad Asim, Daniel P Barry, Margaret M Allaman, Dana M Hardbower, Alberto G Delgado, M Blanca Piazuelo, Bruce A Vallance, Alain P Gobert, Keith T Wilson
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005984 (2016)
Solute carrier family 7 member 2 (SLC7A2) is an inducible transporter of the semi-essential amino acid L-arginine (L-Arg), which has been implicated in immune responses to pathogens. We assessed the role of SLC7A2 in murine infection with Citrobacter
Externí odkaz:
https://doaj.org/article/dde25832be474145b30f534c31096627
Autor:
Kirk S B Bergstrom, Vijay Morampudi, Justin M Chan, Ganive Bhinder, Jennifer Lau, Hyungjun Yang, Caixia Ma, Tina Huang, Natasha Ryz, Ho Pan Sham, Maryam Zarepour, Colby Zaph, David Artis, Meera Nair, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005108 (2015)
Enterohemorrhagic Escherichia coli and related food and waterborne pathogens pose significant threats to human health. These attaching/effacing microbes infect the apical surface of intestinal epithelial cells (IEC), causing severe diarrheal disease.
Externí odkaz:
https://doaj.org/article/9d1ad340b91445fd91d1e0097a410334
Autor:
Brandon Sit, Shauna M Crowley, Kirandeep Bhullar, Christine Chieh-Lin Lai, Calvin Tang, Yogesh Hooda, Charles Calmettes, Husain Khambati, Caixia Ma, John H Brumell, Anthony B Schryvers, Bruce A Vallance, Trevor F Moraes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005107 (2015)
Efficient acquisition of extracellular nutrients is essential for bacterial pathogenesis, however the identities and mechanisms for transport of many of these substrates remain unclear. Here, we investigate the predicted iron-binding transporter AfuA
Externí odkaz:
https://doaj.org/article/8a537c844cf04e78a4e9b514d37279a5
Autor:
Philipp Rausch, Natalie Steck, Abdulhadi Suwandi, Janice A Seidel, Sven Künzel, Kirandeep Bhullar, Marijana Basic, Andre Bleich, Jill M Johnsen, Bruce A Vallance, John F Baines, Guntram A Grassl
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005008 (2015)
Glycans play important roles in host-microbe interactions. Tissue-specific expression patterns of the blood group glycosyltransferase β-1,4-N-acetylgalactosaminyltransferase 2 (B4galnt2) are variable in wild mouse populations, and loss of B4galnt2 e
Externí odkaz:
https://doaj.org/article/2e4e4361c7a545d38c964e42bf2c2c9b