Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Bruce A Freeman"'
Autor:
Marco Fazzari, Andrés Trostchansky, Francisco J Schopfer, Sonia R Salvatore, Beatriz Sánchez-Calvo, Dario Vitturi, Raquel Valderrama, Juan B Barroso, Rafael Radi, Bruce A Freeman, Homero Rubbo
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84884 (2014)
Extra virgin olive oil (EVOO) and olives, key sources of unsaturated fatty acids in the Mediterranean diet, provide health benefits to humans. Nitric oxide (•NO) and nitrite (NO2 (-))-dependent reactions of unsaturated fatty acids yield electrophil
Externí odkaz:
https://doaj.org/article/420b2b2b33494c3eaad47a584a8fb675
Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives.
Autor:
Chiara Cipollina, Sonia R Salvatore, Matthew F Muldoon, Bruce A Freeman, Francisco J Schopfer
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94836 (2014)
Dietary ω-3 polyunsaturated fatty acids (PUFAs) decrease cardiovascular risk via suppression of inflammation. The generation of electrophilic α,β-unsaturated ketone derivatives of the ω-3 PUFAs docosahexaenoic acid (DHA) and docosapentaenoic acid
Externí odkaz:
https://doaj.org/article/718d0e24d07241b5a3f63966a6dba529
Autor:
Valerie B. O’Donnell, Nils H. Schebb, Ginger L. Milne, Michael P. Murphy, Christopher P. Thomas, Dieter Steinhilber, Stacy L. Gelhaus, Hartmut Kühn, Michael H. Gelb, Per-Johan Jakobsson, Ian A. Blair, Robert C. Murphy, Bruce A. Freeman, Alan R. Brash, Garret A. FitzGerald
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/be32bdf8db4a483a9d4567d68f0e996c
Autor:
Fabliha A. Chowdhury, Nicole Colussi, Malini Sharma, Katherine C. Wood, Julia Z. Xu, Bruce A. Freeman, Francisco J. Schopfer, Adam C. Straub
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102941- (2023)
Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients display a plethora of disease-associated complications including anemia, oxidative stress, steril
Externí odkaz:
https://doaj.org/article/e1bc2e80353f4d6091066d02a5726433
Autor:
Roberto Di Maio, Matthew T. Keeney, Veronika Cechova, Amanda Mortimer, Ahssan Sekandari, Pascal Rowart, J. Timothy Greenamyre, Bruce A. Freeman, Marco Fazzari
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract To date there are no therapeutic strategies that limit the progression of Parkinson’s disease (PD). The mechanisms underlying PD-related nigrostriatal neurodegeneration remain incompletely understood, with multiple factors modulating the c
Externí odkaz:
https://doaj.org/article/5eee1875d5414f4f93c5537ba12898e0
Autor:
Lisa Hong, Dennis C. Braden, Yaoning Zhao, John J. Skoko, Fei Chang, Steven R. Woodcock, Crystall Uvalle, Allison Casey, Katherine Wood, Sonia R. Salvatore, Alparslan Asan, Trey Harkness, Adeola Fagunloye, Mortezaali Razzaghi, Adam Straub, Maria Spies, Daniel D. Brown, Adrian V. Lee, Francisco Schopfer, Bruce A. Freeman, Carola A. Neumann
Publikováno v:
Redox Biology, Vol 66, Iss , Pp 102856- (2023)
Nitro fatty acids (NO2-FAs) are endogenously generated lipid signaling mediators from metabolic and inflammatory reactions between conjugated diene fatty acids and nitric oxide or nitrite-derived reactive species. NO2-FAs undergo reversible Michael a
Externí odkaz:
https://doaj.org/article/74e2d4a459964b33908f0fc33cbe7493
Akademický článek
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Autor:
Victoria A. Heinrich, Crystal Uvalle, Michelle L. Manni, Kelvin Li, Steven J. Mullett, Sri Ramya Donepudi, Jason Clader, Adam Fitch, Madeline Ellgass, Veronika Cechova, Shulin Qin, Fernando Holguin, Bruce A. Freeman, Barbara A. Methé, Alison Morris, Stacy L. Gelhaus
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2023)
Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have altered production of metabolites that may influence lung function and inflammatory response
Externí odkaz:
https://doaj.org/article/ca9aa240e77746a392708e4e1d31ec30
Publikováno v:
American Journal of Medical Genetics. Part A; Nov2024, Vol. 194 Issue 11, p1-4, 4p
Autor:
Peng Wang, Meaghan E. Killeen, Tina L. Sumpter, Laura K. Ferris, Louis D. Falo, Jr., Bruce A. Freeman, Francisco J. Schopfer, Alicia R. Mathers
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101987- (2021)
Psoriasis is a chronic inflammatory skin disease with no cure. Although the origin of psoriasis and its underlying pathophysiology remain incompletely understood, inflammation is a central mediator of disease progression. In this regard, electrophili
Externí odkaz:
https://doaj.org/article/4b0d7cf207144e3e87124caa4fa7109b