Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bruce A, Cornell"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2402
Tethered bilayer lipid membranes (tBLMs) anchored to a solid substrate can be prepared and individual triangular voltage ramps from zero to 500 mV with a period of 2-10 ms applied to give membrane voltage dependencies with and without the addition of
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2402
Monitoring the changes in membrane conductance using electrical impedance spectroscopy is the platform of membrane-based biosensors in order to detect a specific target molecule. These biosensors represent the amalgamation of an electrical conductor
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2402
Model lipid bilayers tethered to a gold substrate with molecular tethers are constructed. The conductance versus temperature dependence curve is then obtained. Here, a method to measure the activation energy for translocation of an ion through existi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2402
Because they are firmly anchored to a noble metal substrate, tethered bilayer lipid membranes (tBLMs) are considerably more robust than supported lipid bilayers such as black lipid membranes (BLMs) (Cranfield et al. Biophys J 106:182-189, 2014). The
Autor:
Heba Al Khamici, Louise J Brown, Khondker R Hossain, Amanda L Hudson, Alxcia A Sinclair-Burton, Jane Phui Mun Ng, Elizabeth L Daniel, Joanna E Hare, Bruce A Cornell, Paul M G Curmi, Mary W Davey, Stella M Valenzuela
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e115699 (2015)
The Chloride Intracellular Ion Channel (CLIC) family consists of six evolutionarily conserved proteins in humans. Members of this family are unusual, existing as both monomeric soluble proteins and as integral membrane proteins where they function as
Externí odkaz:
https://doaj.org/article/b54dca6279c64ebfa0472ffbf7704d02
Publikováno v:
Membranes, Vol 6, Iss 4, p 51 (2016)
The Chloride Intracellular Ion Channel (CLIC) family consists of six conserved proteins in humans. These are a group of enigmatic proteins, which adopt both a soluble and membrane bound form. CLIC1 was found to be a metamorphic protein, where under s
Externí odkaz:
https://doaj.org/article/3a0dd246e6c8433086a7ea6d4692f1d7
Autor:
Stella M Valenzuela, Heba Alkhamici, Louise J Brown, Oscar C Almond, Sophia C Goodchild, Sonia Carne, Paul M G Curmi, Stephen A Holt, Bruce A Cornell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56948 (2013)
The Chloride Intracellular ion channel protein CLIC1 has the ability to spontaneously insert into lipid membranes from a soluble, globular state. The precise mechanism of how this occurs and what regulates this insertion is still largely unknown, alt
Externí odkaz:
https://doaj.org/article/22921ad584fd4e9ab880afbb11a6822c
Publikováno v:
CDC
This paper deals with the construction and analysis of distributed dynamical models for a novel biosensor that exploits the molecular switching mechanism of biological ion channels. The rate of change of the concentration of the chemical species in t