7. INAPPROPRIATE PRESCRIPTION OF ALLOPURINOL AND FEBUXOSTAT AND RISK OF ADVERSE EVENTS IN THE ELDERLY: RESULTS FROM THE REPOSI REGISTRY

Autor: Pasina, L, Brucato, AL, Djade, CD, Di Corato, P, Ghidoni, S, Tettamanti, M, Franchi, C, Salerno, F, CORRAO, Salvatore, Marengoni, A, Marcucci, M, Mannucci, PM, Nobili, A, REPOSI, Investigators, BARBAGALLO, Mario, DOMINGUEZ RODRIGUEZ, Ligia Juliana

Purpose To investigate the prevalence of xanthine oxidase (XO) inhibitors prescription at admission and discharge in elderly hospital in-patients, to analyze the appropriateness of their use in relation to evidence-based indications, to evaluate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3658::f56c4caf59d6fcac511ae7dba58c48ec
http://hdl.handle.net/10447/104666

The evaluation of myocarditis in patients with Still's disease; clinical findings from the multicentre international AIDA Network Still's Disease Registry.

Autor: Ruscitti P; Piero Ruscitti, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Di Cola I; Ilenia Di Cola, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Vitale A; Antonio Vitale, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Caggiano V; Valeria Caggiano, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Palumbo P; Pierpaolo Palumbo, Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, L'Aquila, Italy., Di Cesare E; Ernesto Di Cesare, Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, L'Aquila, Italy., Torres-Ruiz J; Jiram Torres-Ruiz, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Guaracha-Basañez GA; Guillermo Arturo Guaracha-Basañez, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Martín-Nares E; Eduardo Martín-Nares, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Ciccia F; Francesco Ciccia, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Iacono D; Daniela Iacono, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Riccio F; Flavia Riccio, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Maggio MC; Maria Cristina Maggio, University Department of Health Promotion, Mother and Child Care, Internal Medicine Italy., Tharwat S; Samar Tharwat, Rheumatology and Immunology Unit, Internal Medicine Department, Mansoura University, Mansoura, Egypt; Department of Internal Medicine, Faculty of Medicine, Horus University, New Damietta, Egypt., Hashad S; Soad Hashad, Rheumatology Department, Tripoli Children Hospital, Tripoli, Libya., Rigante D; Donato Rigante, Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica Sacro Cuore, Rome, Italy., Ortolan A; Augusta Ortolan, Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Giardini HAM; Henrique A. Mayrink Giardini, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Parente de Brito Antonelli I; Isabele Parente de Brito Antonelli, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Cordeiro RA; Rafael Alves Cordeiro, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Giacomelli R; Roberto Giacomelli, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Navarini L; Luca Navarini, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Berardicurti O; Onorina Berardicurti, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Conforti A; Alessandro Conforti, U.O. Medicina Generale, Ospedale San Paolo di Civitavecchia, ASL Roma 4, Civitavecchia, Rome, Italy., Opris-Belinski D; Daniela Opris-Belinski, Rheumatology and Internal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Sota J; Jurgen Sota, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Gaggiano C; Carla Gaggiano, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Lopalco G; Giuseppe Lopalco, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., Iannone F; Fiorenzo Iannone, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., La Torre F; Francesco La Torre, Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Mastrorilli V; Violetta Mastrorilli, Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Govoni M; Marcello Govoni, Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna-Ferrara, University of Ferrara, Ferrara, Italy., Ruffilli F; Francesca Ruffilli, Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna-Ferrara, University of Ferrara, Ferrara, Italy., Emmi G; Giacomo Emmi, Department of Medical, Surgical and Health Sciences, University of Trieste, Italy, and Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy.; Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical entre, Melbourne, Australia., Biancalana E; Edoardo Biancalana, Department of Experimental and Clinical Medicine, Florence, Italy., Sfikakis PP; Petros P. Sfikakis, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Tektonidou M; Maria Tektonidou, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Hernández-Rodríguez J; José Hernández-Rodríguez, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Gómez-Caverzaschi V; Verónica Gómez-Caverzaschi, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Gündüz ÖS; Özgül Soysal Gündüz, Department of Internal Medicine, Division of Rheumatology, Celal Bayar University School of Medicine, Manisa, Turkey., Conti G; Giovanni Conti, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy., Patroniti S; Serena Patroniti, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy., Gidaro A; Antonio Gidaro, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy., Bartoli A; Arianna Bartoli, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy., Olivieri AN; Alma Nunzia Olivieri, Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Gicchino MF; M. Francesca Gicchino, Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Brucato AL; Antonio Luca Brucato, Pediatric Unit, Fatebenefratelli Hospital, Milan, Italy., Dagna L; Lorenzo Dagna, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Tomelleri A; Alessandro Tomelleri, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Campochiaro C; Corrado Campochiaro, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., De Paulis A; Amato De Paulis, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy; Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, University of Naples Federico II, Naples, Italy., Mormile I; Ilaria Mormile, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Della Casa F; Francesca Della Casa, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Direskeneli H; Haner Direskeneli, Department of Internal Medicine, Division of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey., Alibaz-Oner F; Fatma Alibaz-Oner, Department of Internal Medicine, Division of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey., Karamanakos A; Anastasios Karamanakos, Department of Rheumatology, 'Evangelismos' General Hospital, Athens, Greece., Dimouli A; Aikaterini Dimouli, Department of Rheumatology, 'Evangelismos' General Hospital, Athens, Greece., Ragab G; Gaafar Ragab, Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt; Faculty of Medicine, Newgiza University, 6th of October City, Egypt., Mahmoud Ahmed AA; Ayman Abdelmonem Ahmed Mahmoud, Rheumatology and Clinical Immunology Unit, Internal Medicine Department, Faculty of Medicine, Cairo University, Giza, Egypt., Tufan A; Abdurrahman Tufan, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Kucuk H; Hamit Kucuk, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Kardas R; Riza Kardas, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Batu ED; Ezgi D. Batu, Department of Pediatric Rheumatology, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Ozen S; Seza Ozen, Department of Pediatric Rheumatology, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Wiesik-Szewczyk E; Ewa Wiesik-Szewczyk, Department of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, National Research Institute, Warsaw, Poland., Hinojosa-Azaola A; Andrea Hinojosa-Azaola, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Balistreri A; Alberto Balistreri, Bioengineering and Biomedical Data Science Lab, Department ofMedical Biotechnologies, University of Siena, Siena, Italy, Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Fabiani C; Claudia Fabiani, Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Frediani B; Bruno Frediani, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Cantarini L; Luca Cantarini, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.

Publikováno v: The Journal of rheumatology [J Rheumatol] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.

Lanadelumab in a kidney transplant patient with hereditary angioedema due to C1-inhibitor deficiency and high cardiovascular risk - a case report.

Autor: Gidaro A; Department of Biomedical and Clinical Sciences 'Luigi Sacco,' University of Milan, Luigi Sacco Hospital, Milan, Italy., La Cava L; Department of Biomedical and Clinical Sciences 'Luigi Sacco,' University of Milan, Luigi Sacco Hospital, Milan, Italy., Donadoni M; Department of Biomedical and Clinical Sciences 'Luigi Sacco,' University of Milan, Luigi Sacco Hospital, Milan, Italy., Popescu Janu V; Department of Biomedical and Clinical Sciences 'Luigi Sacco,' University of Milan, Luigi Sacco Hospital, Milan, Italy., Cogliati C; Department of Biomedical and Clinical Sciences 'Luigi Sacco,' University of Milan, Luigi Sacco Hospital, Milan, Italy., Brucato AL; Internal Medicine Department, Fatebenefratelli Hospital, Milan, Italy., Zanichelli A; Operative Unit of Medicine, Angioedema Center, IRCCS Policlinico San Donato, Milan, Italy.; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy., Cancian M; Department of Systems Medicine, University Hospital of Padua, Padua, Italy., Bizzi E; Internal Medicine Department, Fatebenefratelli Hospital, Milan, Italy.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Sep 27; Vol. 15, pp. 1472390. Date of Electronic Publication: 2024 Sep 27 (Print Publication: 2024).

Risk for cancer development in familial Mediterranean fever and associated predisposing factors: an ambidirectional cohort study from the international AIDA Network registries.

Autor: Vitale A; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Caggiano V; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Tufan A; Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Türkiye., Ragab G; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt.; Faculty of Medicine, Newgiza University, 6th of October City, Giza, Egypt., Batu ED; Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Türkiye., Portincasa P; Clinica Medica 'A. Murri', Division of Internal Medicine, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari Aldo Moro, Bari, Italy., Aragona E; Division of Gastroenterology, Ospedali Riuniti Villa Sofia-Vincenzo Cervello, Palermo, Italy., Sota J; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Conti G; Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino', Messina, Italy., De Paulis A; Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy.; Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, University of Naples Federico II, Naples, Italy., Rigante D; Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Rare Diseases and Periodic Fevers Research Center, Università Cattolica del Sacro Cuore, Rome, Italy., Olivieri AN; Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Şahin A; Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty, Sivas, Türkiye., La Torre F; Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Lopalco G; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., Cattalini M; Pediatrics Clinic, University of Brescia and Spedali Civili of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy., Maggio MC; University Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE) 'G. D'Alessandro', University of Palermo, Palermo, Italy., Insalaco A; Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Rome, Italy., Sfikakis PP; Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Athens, Greece., Verrecchia E; Rare Diseases and Periodic Fevers Research Center, Università Cattolica del Sacro Cuore, Rome, Italy.; Department of Aging, Neurological, Orthopedic and Head and Neck Sciences, Fondazione Policlinico Universitario Agostino Gemelli Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy., Yildirim D; Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Türkiye., Kucuk H; Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Türkiye., Kardas RC; Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Türkiye., Laymouna AH; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt., Ghanema M; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt., Saad MA; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt., Sener S; Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Türkiye., Ercan Emreol H; Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Türkiye., Ozen S; Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Türkiye., Jaber N; Clinica Medica 'A. Murri', Division of Internal Medicine, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari Aldo Moro, Bari, Italy., Khalil M; Clinica Medica 'A. Murri', Division of Internal Medicine, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari Aldo Moro, Bari, Italy., Di Ciaula A; Clinica Medica 'A. Murri', Division of Internal Medicine, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari Aldo Moro, Bari, Italy., Gaggiano C; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Malizia G; Division of Gastroenterology, Ospedali Riuniti Villa Sofia-Vincenzo Cervello, Palermo, Italy., Affronti A; Division of Gastroenterology, Ospedali Riuniti Villa Sofia-Vincenzo Cervello, Palermo, Italy., Patroniti S; Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino', Messina, Italy., Romeo M; Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino', Messina, Italy., Sbalchiero J; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Della Casa F; Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Mormile I; Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Silvaroli S; Department of Pediatric Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Gicchino MF; Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Çelik NÇ; Division of Rheumatology, Department of Internal Medicine, Sivas Cumhuriyet University Medical Faculty, Sivas, Türkiye., Tarsia M; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy.; Clinical Pediatrics, Department of Molecular Medicine and Development, University of Siena, Siena, Italy., Karamanakos A; Department of Rheumatology, 'Evangelismos' General Hospital, Athens, Greece., Hernández-Rodríguez J; Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Parronchi P; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Opris-Belinski D; Rheumatology and Internal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Barone P; Pediatric Rheumatology Unit, Department of integrated Maternal-Child and Reproduction Activity AOU 'Policlinico-San Marco', Catania, Italy., Recke A; Department of Dermatology, Allergology and Venerology, University Hospital Schleswig-Holstein, Lübeck, Germany.; Autoinflammatory and Autoimmune Diseases (RITA) Center, European Reference Network (ERN) for Rare Immunodeficiency, Lübeck, Germany., Costi S; Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, University of Milan, Milan, Italy., Sfriso P; Rheumatology Unit, Department of Medicine, University of Padua, Padua, Italy., Giardini HAM; Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Gentileschi S; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Siena, Italy., Wiesik-Szewczyk E; Department of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, National Research Institute, Warsaw, Poland., Vasi I; Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Türkiye., Loconte R; Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Jahnz-Różyk K; Department of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, National Research Institute, Warsaw, Poland., Martín-Nares E; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Torres-Ruiz J; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Cauli A; Rheumatology Unit, Department of Medical Sciences, University and AOU of Cagliari, Cagliari, Italy., Conforti A; Ospedale San Paolo di Civitavecchia, U.O. Medicina Generale, ASL Roma 4, Civitavecchia, Rome, Italy., Emmi G; Department of Medical, Surgical and Health Sciences, University of Trieste, Italy, and Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy.; Centre for Inflammatory Diseases, Department of Medicine, Monash Medical Centre, Monash University, Clayton, VIC, Australia., Li Gobbi F; Rheumatology Unit, Hospital S. 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