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Association of Histologic Parameters with Outcome in C3 Glomerulopathy and Idiopathic Immunoglobulin-Associated Membranoproliferative Glomerulonephritis.

Autor: Lomax-Browne HJ; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Medjeral-Thomas NR; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Barbour SJ; Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada., Gisby J; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Han H; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York., Bomback AS; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York., Fervenza FC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota., Cairns TH; West London Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom., Szydlo R; Department for Immunology and Inflammation, Centre for Haematology, Imperial College London, London, United Kingdom., Tan SJ; Department of Nephrology, The Royal Melbourne Hospital, Parkville, Victoria, Australia., Marks SD; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.; National Institute for Health Research Great Ormond Street Hospital Biomedical Research Centre, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Waters AM; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom., Appel GB; Department of Medicine, Division of Nephrology, Columbia University Irving Medical Center, New York, New York., D'Agati VD; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York., Sethi S; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Nast CC; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California., Bajema I; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Alpers CE; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Fogo AB; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee., Licht C; Division of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada., Fakhouri F; Service of Nephrology and Hypertension, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Cattran DC; Toronto General Research Institute, Division of Nephrology, University of Toronto, Toronto, Ontario, Canada., Peters JE; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Cook HT; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Pickering MC; Department for Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom.

Publikováno v: Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2022 Jul; Vol. 17 (7), pp. 994-1007.

Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.

Autor: Malik TH; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Gitterman DP; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom., Lavin DP; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Lomax-Browne HJ; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Hiemeyer EC; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Moran LB; North West London Pathology, Imperial College Healthcare National Health Service Trust, London W6 8RF, United Kingdom., Boroviak K; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom., Cook HT; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Gilmore AC; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom., Mandwie M; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia., Ahmad A; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia., Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia.; Discipline of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, NSW 2145 Westmead, Australia., Logan GJ; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia., Marchbank KJ; Translational and Clinical Research Institute, The Medical School, Newcastle University, Framlington Place, Newcastle-upon-Tyne NE2 4HH, United Kingdom.; National Renal Complement Therapeutics Centre, Newcastle-upon-Tyne NE1 4LP, United Kingdom., Bradley A; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom., Pickering MC; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom; matthew.pickering@imperial.ac.uk.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 30; Vol. 118 (13).

Serum IgA1 shows increased levels of α 2,6-linked sialic acid in breast cancer.

Autor: Lomax-Browne HJ; School of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK., Robertson C; School of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK., Antonopoulos A; Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK., Leathem AJC; School of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK., Haslam SM; Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK., Dell A; Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK., Dwek MV; School of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK.

Publikováno v: Interface focus [Interface Focus] 2019 Apr 06; Vol. 9 (2), pp. 20180079. Date of Electronic Publication: 2019 Feb 15.

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition.

Autor: Medjeral-Thomas NR; Centre for Complement and Inflammation Research, Imperial College London, London, UK., Troldborg A; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark., Constantinou N; Centre for Complement and Inflammation Research, Imperial College London, London, UK., Lomax-Browne HJ; Centre for Complement and Inflammation Research, Imperial College London, London, UK., Hansen AG; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Willicombe M; Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK., Pusey CD; Renal and Vascular Inflammation Section, Imperial College London, London, UK., Cook HT; Centre for Complement and Inflammation Research, Imperial College London, London, UK., Thiel S; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Pickering MC; Centre for Complement and Inflammation Research, Imperial College London, London, UK.

Publikováno v: Kidney international reports [Kidney Int Rep] 2017 Nov 29; Vol. 3 (2), pp. 426-438. Date of Electronic Publication: 2017 Nov 29 (Print Publication: 2018).