Modulation by 17,20S(OH) 2 pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis.

Autor: Brown Lobbins ML; Department of Pediatrics, University of Tennessee Health Science Center, 50 N. Dunlap, Rm. 461R, Memphis, TN 38103, USA.; Department of Medicine, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA., Slominski AT; Department of Dermatology, University of Alabama at Birmingham, 500 22nd Street South, Birmingham, AL 35294, USA.; Comprehensive Cancer Center, University of Alabama at Birmingham, 1824 6th Avenue, Birmingham, AL 35294, USA.; Birmingham Veterans Affairs Medical Center, 700 19th Street South, Birmingham, AL 35233, USA., Hasty KA; Memphis Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis, TN 38104, USA.; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, 1211 Union Avenue, Suite 520, Memphis, TN 38104, USA., Zhang S; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38103, USA., Miller DD; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38103, USA., Li W; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, TN 38103, USA., Kim TK; Department of Dermatology, University of Alabama at Birmingham, 500 22nd Street South, Birmingham, AL 35294, USA., Janjetovic Z; Department of Dermatology, University of Alabama at Birmingham, 500 22nd Street South, Birmingham, AL 35294, USA., Tuckey RC; School of Molecular Sciences, University of Western Australia, 35 Stirling Highway, Perth 6009, Australia., Scott IO; Department of Medicine, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA., Myers LK; Department of Pediatrics, University of Tennessee Health Science Center, 50 N. Dunlap, Rm. 461R, Memphis, TN 38103, USA.; Department of Medicine, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA., Postlethwaite AE; Department of Medicine, University of Tennessee Health Science Center, 956 Court Avenue, Memphis, TN 38163, USA.; Memphis Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis, TN 38104, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 29; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 29.

Chronic exposure of interleukin-13 suppress the induction of matrix metalloproteinase-1 by tumour necrosis factor α in normal and scleroderma dermal fibroblasts through protein kinase B/Akt.

Autor: Brown Lobbins ML; Department of Pediatrics, University of Tennessee Health Science Center, Division of Connective Tissue Diseases., Shivakumar BR; Veterans Administration Medical Center, Memphis, Tennessee., Postlethwaite AE; Department of Medicine, Division of Connective Tissue Diseases, University of Tennessee Health Science Center, Veterans Administration Medical Center., Hasty KA; Department of Orthopedic Surgery, Division of Connective Tissue Diseases, University of Tennessee Health Science Center, Veterans Administration Medical Center.

Publikováno v: Clinical and experimental immunology [Clin Exp Immunol] 2018 Jan; Vol. 191 (1), pp. 84-95. Date of Electronic Publication: 2017 Oct 02.