Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Brouwers-Vos A"'
Autor:
Isabel Weinhäuser, Diego A. Pereira-Martins, Jacobien R. Hilberink, Annet Brouwers-Vos, Eduardo M. Rego, Gerwin Huls, Jan Jacob Schuringa
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/a6032b8c6c124d25b2bc7e7184f7b3c6
Autor:
Ayşegül Erdem, Silvia Marin, Diego A. Pereira-Martins, Roldán Cortés, Alan Cunningham, Maurien G. Pruis, Bauke de Boer, Fiona A. J. van den Heuvel, Marjan Geugien, Albertus T. J. Wierenga, Annet Z. Brouwers-Vos, Eduardo M. Rego, Gerwin Huls, Marta Cascante, Jan Jacob Schuringa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Acute myeloid leukemia (AML) is genetically a very heterogeneous disease. Here, Erdem et al. uncover heterogeneity in the metabolic landscape of AML and identify Pyruvate dehydrogenase kinase 1 (PDK1) as a targetable determinant of different metaboli
Externí odkaz:
https://doaj.org/article/0f8fe7450b4e4f25a3960cce038a7ad3
Autor:
Maat, Henny, Atsma, Tjerk Jan, Hogeling, Shanna M., Rodríguez López, Aida, Jaques, Jennifer, Olthuis, Mirjam, de Vries, Marcel P., Gravesteijn, Chantal, Brouwers-Vos, Annet Z., van der Meer, Nisha, Datema, Suzan, Salzbrunn, Jonas, Huls, Gerwin, Baas, Roy, Martens, Joost H.A., van den Boom, Vincent, Schuringa, Jan Jacob
Publikováno v:
In iScience 21 May 2021 24(5)
Akademický článek
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Autor:
Albertus T. J. Wierenga, Alan Cunningham, Ayşegül Erdem, Nuria Vilaplana Lopera, Annet Z. Brouwers-Vos, Maurien Pruis, André B. Mulder, Ulrich L. Günther, Joost H. A. Martens, Edo Vellenga, Jan Jacob Schuringa
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background Hypoxia-inducible factors (HIF)1 and 2 are transcription factors that regulate the homeostatic response to low oxygen conditions. Since data related to the importance of HIF1 and 2 in hematopoietic stem and progenitors is conflict
Externí odkaz:
https://doaj.org/article/bc991f9e636e41c6936e5e05d890d9b1
Autor:
Mattes, Katharina, Geugien, Marjan, Korthuis, Patrick M., Brouwers-Vos, Annet Z., Fehrmann, Rudolf S.N., Todorova, Tihomira I., Steidl, Ulrich, Vellenga, Edo, Schepers, Hein
Publikováno v:
In Experimental Hematology May 2019 73:38-49
Autor:
Henny Maat, Tjerk Jan Atsma, Shanna M. Hogeling, Aida Rodríguez López, Jennifer Jaques, Mirjam Olthuis, Marcel P. de Vries, Chantal Gravesteijn, Annet Z. Brouwers-Vos, Nisha van der Meer, Suzan Datema, Jonas Salzbrunn, Gerwin Huls, Roy Baas, Joost H.A. Martens, Vincent van den Boom, Jan Jacob Schuringa
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102435- (2021)
Summary: In an attempt to unravel functionality of the non-canonical PRC1.1 Polycomb complex in human leukemogenesis, we show that USP7 and TRIM27 are integral components of PRC1.1. USP7 interactome analyses show that PRC1.1 is the predominant Polyco
Externí odkaz:
https://doaj.org/article/8823b96dd2fd489eb61108bb1f803e5e
Autor:
Antonelli, Antonella, Noort, Willy A., Jaques, Jenny, de Boer, Bauke, de Jong-Korlaar, Regina, Brouwers-Vos, Annet Z., Lubbers-Aalders, Linda, van Velzen, Jeroen F., Bloem, Andries C., Yuan, Huipin, de Bruijn, Joost D., Ossenkoppele, Gert J., Martens, Anton C.M., Vellenga, Edo, Groen, Richard W.J., Schuringa, Jan Jacob
Publikováno v:
In Blood 22 December 2016 128(25):2949-2959
Autor:
Vincent van den Boom, Henny Maat, Marjan Geugien, Aida Rodríguez López, Ana M. Sotoca, Jennifer Jaques, Annet Z. Brouwers-Vos, Fabrizia Fusetti, Richard W.J. Groen, Huipin Yuan, Anton C.M. Martens, Hendrik G. Stunnenberg, Edo Vellenga, Joost H.A. Martens, Jan Jacob Schuringa
Publikováno v:
Cell Reports, Vol 14, Iss 2, Pp 332-346 (2016)
Polycomb proteins are classical regulators of stem cell self-renewal and cell lineage commitment and are frequently deregulated in cancer. Here, we find that the non-canonical PRC1.1 complex, as identified by mass-spectrometry-based proteomics, is cr
Externí odkaz:
https://doaj.org/article/1c182e807a2e418b846ccabd84b196b5
Autor:
Bosman, Matthieu Cornelis Johannes, Schepers, Hein, Jaques, Jennifer, Brouwers-Vos, Annet Zwaantien, Quax, Wim Johannes, Schuringa, Jan Jacob *, Vellenga, Edo
Publikováno v:
In Blood 13 November 2014 124(20):3130-3140