Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brooks R, Sunday"'
Publikováno v:
Journal of capillary electrophoresis and microchip technology. 8(5-6)
High-performance capillary electrophoresis (HPCE) has emerged over the past 20 years as a powerful multidimensional separation tool that is orthogonal to HPLC and comparable to sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) slab
Publikováno v:
Archives of biochemistry and biophysics. 280(2)
Smooth muscle myosin light chain kinase (MLCK) is activated by calcium—calmodulin and, in turn, phosphorylates and activates the smooth muscle actomyosin ATPase, resulting in muscle contraction. The amino acid sequence of the regulatory domain of M
Publikováno v:
Journal of Medicinal Chemistry. 25:742-745
Several known antiallergic agents, including cromolyn sodium and a series of pyrido[2,1-b]quinazolines, inhibit human alkaline phosphatase (ALP), a membranal enzyme associated with calcium uptake in certain tissues. A comparison of ALP and rat passiv
Publikováno v:
Journal of Medicinal Chemistry. 16:585-588
Publikováno v:
Journal of Medicinal Chemistry. 23:964-966
A series of substituted 10-oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acids was prepared and evaluated as antiallergy agents. The 8-chloro and unsubstituted analogues were more potent that cromolyn sodium and doxantrazole intravenously in the
Publikováno v:
Chemischer Informationsdienst. 13
Several known antiallergic agents, including cromolyn sodium and a series of pyrido[2,1-b]quinazolines, inhibit human alkaline phosphatase (ALP), a membranal enzyme associated with calcium uptake in certain tissues. A comparison of ALP and rat passiv
Publikováno v:
Chemischer Informationsdienst. 12
Publikováno v:
Chemischer Informationsdienst. 10
A new series of 11-oxo-11H-pyrido[2,1-b]quinazolinecarboxylic acids and related analogues has been synthesized and evaluated as potential antiallergy agents. In the rat PCA test, 11-oxo-11H-pyrido[2,1--b]quinazoline-8-carboxylic acid is orally active
Publikováno v:
Journal of medicinal chemistry. 22(1)
A new series of 11-oxo-11H-pyrido[2,1-b]quinazolinecarboxylic acids and related analogues has been synthesized and evaluated as potential antiallergy agents. In the rat PCA test, 11-oxo-11H-pyrido[2,1--b]quinazoline-8-carboxylic acid is orally active
Autor:
Daniel L. Gawlak, Edward K. Kusner, David J. Herzig, Brooks R. Sunday, P. R. Schumann, Charles F. Schwender
Publikováno v:
Journal of medicinal chemistry. 22(6)
A series of substituted 11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acids were prepared and evaluated as antiallergy agents. Several analogues were orally active. 2-Methyl-11-oxo-11H-pyrido[2,1-b]quinoazoline-8-carboxylic acid (6) was superior t