Zobrazeno 1 - 10 of 1 336 pro vyhledávání: '"Brooks DJ"'
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Imaging synaptic microstructure and synaptic loss in vivo in early Alzheimer’s Disease
Autor: Venkataraman, A, Bishop, C, Mansur, A, Rizzo, G, Lewis, Y, Kocagoncu, E, Lingford-Hughes, A, Huiban, M, Passchier, J, Rowe, JB, Tsukada, H, Brooks, DJ, Martarello, L, Comley, RA, Chen, L, Hargreaves, R, Schwarz, AJ, Gunn, RN, Rabiner, E, Matthews, PM
Background Synaptic loss and neurite dystrophy are early events in Alzheimer’s Disease (AD). We aimed to characterise early synaptic microstructural changes in vivo. Methods MRI neurite orientation dispersion and density imaging (NODDI) and diffusi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::e0728b485616a9a682d643074deace6e
http://hdl.handle.net/10044/1/93156
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9
Widespread cell stress and mitochondrial dysfunction in early Alzheimer’s Disease
Autor: Venkataraman, A, Mansur, A, Rizzo, G, Bishop, C, Lewis, Y, Kocagoncu, E, Lingford-Hughes, A, Huiban, M, Passchier, J, Rowe, J, Tsukada, H, Brooks, DJ, Martarello, L, Comley, RA, Chen, L, Schwarz, AJ, Hargreaves, R, Gunn, R, Rabiner, E, Matthews, PM
Cell stress and impaired oxidative phosphorylation are central to mechanisms of synaptic loss and neurodegeneration in the cellular pathology of Alzheimer’s disease (AD). We quantified the in vivo density of the endoplasmic reticulum stress marker,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::a20e34cc6bdfde3ae34ac4f3fd437164
http://hdl.handle.net/10044/1/92580
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Plný text Recenzováno Digitální knihovna AV ČR
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