Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brooke Simonton"'
Autor:
Douglas Yao, Loic Binan, Jon Bezney, Brooke Simonton, Jahanara Freedman, Chris J. Frangieh, Kushal Dey, Kathryn Geiger-Schuller, Basak Eraslan, Alexander Gusev, Aviv Regev, Brian Cleary
Publikováno v:
bioRxiv
Pooled CRISPR screens with single-cell RNA-seq readout (Perturb-seq) have emerged as a key technique in functional genomics, but are limited in scale by cost and combinatorial complexity. Here, we reimagine Perturb-seq’s design through the lens of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29580a2768c2e9ea79bc17e8976bcd0
https://europepmc.org/articles/PMC9900787/
https://europepmc.org/articles/PMC9900787/
Autor:
Ehsan Habibi, Fei Chen, Evan Murray, Aviv Regev, Brian Cleary, Anubhav Sinha, Jamie L. Marshall, Jon Bezney, Eric S. Lander, Shahul Alam, Brooke Simonton
Publikováno v:
Nature Biotechnology. 39:936-942
Recent methods for spatial imaging of tissue samples can identify up to ~100 individual proteins1–3 or RNAs4–10 at single-cell resolution. However, the number of proteins or genes that can be studied in these approaches is limited by long imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a4ebcf92401318b20e964a8af5df89
https://doi.org/10.1038/s41587-021-00883-x
https://doi.org/10.1038/s41587-021-00883-x
Autor:
Natalie Piehl, Lynn van Olst, Abhirami Ramakrishnan, Victoria Teregulova, Brooke Simonton, Ziyang Zhang, Emma Tapp, Divya Channappa, Hamilton Oh, Patricia M. Losada, Jarod Rutledge, Alexandra N. Trelle, Elizabeth C. Mormino, Fanny Elahi, Douglas R. Galasko, Victor W. Henderson, Anthony D. Wagner, Tony Wyss-Coray, David Gate
Publikováno v:
Cell. 185(26)
Cerebrospinal fluid (CSF) contains a tightly regulated immune system. However, knowledge is lacking about how CSF immunity is altered with aging or neurodegenerative disease. Here, we performed single-cell RNA sequencing on CSF from 45 cognitively no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f217ab364318591d3af758444def5a4
https://pubmed.ncbi.nlm.nih.gov/36516855
https://pubmed.ncbi.nlm.nih.gov/36516855
Autor:
Brendan Blumenstiel, Abdul Karim Sesay, David Hong, Maegan Harden, Michelle Cipicchio, Brooke Simonton, Madikay Senghore, Stacey Gabriel, Jon Bezney, James A. Hay, Brian Cleary, Michael J. Mina, Aviv Regev
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
The ongoing pandemic of SARS-CoV-2, a novel coronavirus, caused over 3 million reported cases of coronavirus disease 2019 (COVID-19) and 200,000 reported deaths between December 2019 and April 20201. Cases and deaths will increase as the virus contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8feee99050d3af4f7480e0746a8216bf
https://doi.org/10.1126/scitranslmed.abf1568
https://doi.org/10.1126/scitranslmed.abf1568
Autor:
Abdul Karim Sesay, Brian Cleary, Brendan Blumenstiel, Brooke Simonton, Stacey Gabriel, Michelle Cipicchio, Aviv Regev, Jon Bezney, David Hong, Michael J. Mina, Madikay Senghore, Maegan Harden, James A. Hay
Publikováno v:
Science Translational Medicine
Simple group testing designs to improve SARS-CoV-2 surveillance in resource-constrained settings are identified using modeling and experimental data.
Batch testing for SARS-CoV-2 Frequent and accurate RT-PCR–based testing is essential for prev
Batch testing for SARS-CoV-2 Frequent and accurate RT-PCR–based testing is essential for prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0131c2f41e8ed7327c27d5b0214004be
https://pubmed.ncbi.nlm.nih.gov/33619080
https://pubmed.ncbi.nlm.nih.gov/33619080
Autor:
Brooke Simonton, Ehsan Habibi, Jamie L. Marshall, Ameya Sinha, Eric S. Lander, Brian Cleary, Alam S, Aviv Regev, Jon Bezney, Evan Murray, Feng Chen
Tissue and organ function rely on the organization of cells and molecules in specific spatial structures. In order to understand these structures and how they relate to tissue function in health and disease, we would ideally be able to rapidly profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625f9247d4497abfaa959118c66efb7d
https://doi.org/10.1101/743039
https://doi.org/10.1101/743039
Autor:
Brian, Cleary, Brooke, Simonton, Jon, Bezney, Evan, Murray, Shahul, Alam, Anubhav, Sinha, Ehsan, Habibi, Jamie, Marshall, Eric S, Lander, Fei, Chen, Aviv, Regev
Publikováno v:
Nature biotechnology. 39(8)
Recent methods for spatial imaging of tissue samples can identify up to ~100 individual proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfc69aa146dd339f7c4e2e7c6eae54ea
https://pubmed.ncbi.nlm.nih.gov/34099935
https://pubmed.ncbi.nlm.nih.gov/34099935