Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Brooke Pallas"'
Autor:
Soundara Viveka Thangaraj, Adel Ghnenis, Brooke Pallas, Arpita Kalla Vyas, Brigid Gregg, Vasantha Padmanabhan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Lipids play a critical role in neonate development and breastmilk is the newborn’s major source of lipids. Milk lipids directly influence the neonate plasma lipid profile. The milk lipidome is dynamic, influenced by maternal factors and re
Externí odkaz:
https://doaj.org/article/04dea998628d4f828347517ceb41d395
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Gestational hyperandrogenism is a risk factor for adverse maternal and offspring outcomes with effects likely mediated in part via disruptions in maternal lipid homeostasis. Using a translationally relevant sheep model of gestational testost
Externí odkaz:
https://doaj.org/article/376da02f908f4cb28ba81eafcec29842
Autor:
Dongshan Yang, Xiubin Liang, Brooke Pallas, Mark Hoenerhoff, Zhuoying Ren, Renzhi Han, Jifeng Zhang, Y. Eugene Chen, Jian-Ping Jin, Fei Sun, Jie Xu
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Cystic Fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation is the deletion of phenylalanine residue at position 508 (
Externí odkaz:
https://doaj.org/article/405360fdcde0447cba734889d07437c2
Autor:
Jie Xu, Jifeng Zhang, Dongshan Yang, Jun Song, Brooke Pallas, Chen Zhang, Jiafen Hu, Xuwen Peng, Neil D. Christensen, Renzhi Han, Y. Eugene Chen
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The rabbit is a classic animal model for biomedical research, but the production of gene targeted transgenic rabbits had been extremely challenging until the recent advent of gene editing tools. More than fifty gene knockout or knock-in rabbit models
Externí odkaz:
https://doaj.org/article/b7d2f4f73b154473b62748d99eb7cc44
Autor:
Jun Song, Brooke Pallas, Dongshan Yang, Jifeng Zhang, Yash Agarwal, Y. Eugene Chen, Moses Bility, Jie Xu
Publikováno v:
Applied Sciences, Vol 10, Iss 20, p 7369 (2020)
Production of immunodeficient (ID) models in non-murine animal species had been extremely challenging until the advent of gene-editing tools: first zinc finger nuclease (ZFN), then transcription activator-like effector nuclease (TALEN), and most rece
Externí odkaz:
https://doaj.org/article/4b8476c944224a0180f2159f872d4da4
Autor:
Bo Yang, Linyuan Ma, Yui Koike, Brooke Pallas, Ying Yang, Mark J. Hoenerhoff, Tomonari Koike, Cheng Deng, Jifeng Zhang, Jie Xu, Y. Eugene Chen, Changzhi Zhao, Luan Wen, Jun Song, Patrick A Lester, Dongshan Yang
Publikováno v:
Stem Cell Reports
Summary Loss-of-function mutations in the forkhead box N1 (FOXN1) gene lead to nude severe combined immunodeficiency, a rare inherited syndrome characterized by athymia, severe T cell immunodeficiency, congenital alopecia, and nail dystrophy. We rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31909ed8b84b52ba339878069ebcfc4f
http://europepmc.org/articles/PMC7940256
http://europepmc.org/articles/PMC7940256
Publikováno v:
J Am Assoc Lab Anim Sci
The combination of bedding substrate and nesting material within the microenvironment of mice is an important consideration for animal care programs in regard to optimizing animal wellbeing. We used 3 general or breeding mouse colonies in our institu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3db67321d8a50fb04bf1f9048e9e07
https://doi.org/10.30802/aalas-jaalas-20-000036
https://doi.org/10.30802/aalas-jaalas-20-000036
Autor:
Dawn M Keys, Joe D Sanders, Michael P Bradley, Zachary T. Freeman, Portia S Allen, Elizabeth J Vernasco-Price, Brooke Pallas
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 59:496-502
Bedding material is a critical component of the mouse environment and affects animal wellbeing and research integrity. Corn cob (CC) bedding has been a common bedding choice in research despite several potential negative aspects of its use. We invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e51d8486d4abf0def95d56cee9190a6
https://doi.org/10.30802/aalas-jaalas-19-000151
https://doi.org/10.30802/aalas-jaalas-19-000151
Autor:
Dongshan Yang, Moses T. Bility, Jie Xu, Yash Agarwal, Brooke Pallas, Jifeng Zhang, Jun Song, Y. Eugene Chen
Publikováno v:
Applied Sciences, Vol 10, Iss 7369, p 7369 (2020)
Production of immunodeficient (ID) models in non-murine animal species had been extremely challenging until the advent of gene-editing tools: first zinc finger nuclease (ZFN), then transcription activator-like effector nuclease (TALEN), and most rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da79800ec3dc41d82c4b2860b92131d9
https://www.mdpi.com/2076-3417/10/20/7369
https://www.mdpi.com/2076-3417/10/20/7369
Publikováno v:
University of Michigan Undergraduate Research Journal. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e93500fccb76f698d2969e8a4b68b6f
https://doi.org/10.3998/umurj.16481002.0013.011
https://doi.org/10.3998/umurj.16481002.0013.011