Výsledky vyhledávání - "Brooke M Devries"

Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice

Autor: Brooke M Devries, Crystal Trang, Pamela L. Mellon, Jessica Sora Lee, Rachel Larder, Rachael J. Hu, Hanne M. Hoffmann, Daniel D. Clark

Publikováno v: Neuroendocrinology. 108:328-342

There is an increasing trend in studies utilizing cell-specific deletion of genes through conditional gene deletion by CRE recombination. Despite numerous advantages, this strategy also has limitations such as ectopic CRE-expression and germline reco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5eda33e3b1452a1af8e6e3bb273c7cd
https://doi.org/10.1159/000497791

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The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice

Autor: Michael R. Gorman, Jeffrey W. Doser, Joseph A Breuer, Jessica Sora Lee, David K. Welsh, Austin Y Chin, Duong Nguyen, Hanne M. Hoffmann, Jason D. Meadows, Alexandra M. Yaw, Haley J Oosterhouse, Pamela L. Mellon, Karen J. Tonsfeldt, Crystal Trang, Brooke M Devries

Publikováno v: J Neurosci Res

The homeodomain transcription factors sine oculis homeobox 3 (Six3) and ventral anterior homeobox 1 (Vax1) are required for brain development. Their expression in specific brain areas is maintained in adulthood, where their functions are poorly under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52bb9e5eff9d33a767b57665168b3f1
https://pubmed.ncbi.nlm.nih.gov/34212416

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The Transcription Factor Ventral Anterior Homeobox 1 Modulates Circadian Time-Keeping and Fertility Through Direct Regulation of Vasoactive Intestinal Polypeptide Expression in the Suprachiasmatic Nucleus

Autor: Michael R. Gorman, Joseph A Breuer, Alexandra M. Yaw, Hanne M. Hoffmann, Lorenzo F. Sempere, Laura J Cui, Tulasi Talluri, Brooke Jackson, Pamela L. Mellon, Duong Nguyen, Emily V. Ho, Brooke M Devries

Publikováno v: Journal of the Endocrine Society

Light provides the primary timing signal that enables fine-tuned behavioral and hormonal entrainment of circadian rhythms to the environment. Light is transmitted from the eye to the brain through the retinohypothalamic tract, where one target is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aac00ccd00f762dc8f8762e75d723f
https://doi.org/10.1210/jendso/bvab048.1134

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