Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brooke Laster"'
Autor:
Kylene P. Daily, Asmaa Badr, Mostafa Eltobgy, Shady Estfanous, Owen Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew McNamara, Kaitlin Hamilton, Samuel Houle, Spandan Gupta, Gauruv A. Gupta, Shruthi Madhu, Julie Fitzgerald, Abbey A. Saadey, Brooke Laster, Pearlly Yan, Amy Webb, Xiaoli Zhang, Maciej Pietrzak, Olga N. Kokiko-Cochran, Hazem E. Ghoneim, Amal O. Amer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is the sixth leading cause of death in the USA. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD patients. Accumulating evidence suggests a cr
Externí odkaz:
https://doaj.org/article/e9004d48993349bc9f739f58c680a79a
Autor:
Abbey A. Saadey, Amir Yousif, Nicole Osborne, Roya Shahinfar, Yu-Lin Chen, Brooke Laster, Meera Rajeev, Parker Bauman, Amy Webb, Hazem E. Ghoneim
Publikováno v:
Nature Immunology. 24:280-294
T cell dysfunctionality prevents the clearance of chronic infections and cancer. Furthermore, epigenetic programming in dysfunctional CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f1a9b30c587e32affa9c51b434a011
https://doi.org/10.1038/s41590-022-01384-y
https://doi.org/10.1038/s41590-022-01384-y
Autor:
Hazem E. Ghoneim, Abbey A Saadey, Amir Yousif, Nicole Osborne, Yu-Lin Chen, Brooke Laster, Ahmed Zayed, Parker Bauman
Publikováno v:
The Journal of Immunology. 208:121.10-121.10
Epigenetic scarring of exhausted T cells (Tex) remains a major obstacle to achieving durable responses by T cell immunotherapies. While we established that de novo DNA methylation programs are causally linked to T cell’s full exhaustion and poor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6599cd6e7dc61586d704e5e787de98f9
https://doi.org/10.4049/jimmunol.208.supp.121.10
https://doi.org/10.4049/jimmunol.208.supp.121.10