Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brooke L Gates"'
Autor:
Amelia D Wallace, Thomas A Sasani, Jordan Swanier, Brooke L Gates, Jeff Greenland, Brent S Pedersen, Katherine E Varley, Aaron R Quinlan
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0241253 (2021)
A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. Long-read sequencing technologies, such as Oxford Nanopore's MinION,
Externí odkaz:
https://doaj.org/article/b40febd6e2ea4665b168e7184b3bf972
Autor:
Ozlen Balcioglu, Brooke L. Gates, David W. Freeman, Berhane M. Hagos, Elnaz Mirzaei Mehrabad, David Ayala-Talavera, Benjamin T. Spike
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Cell state control is crucial for normal tissue development and cancer cell mimicry of stem/progenitor states, contributing to tumor heterogeneity, therapy resistance, and progression. Here, we demonstrate that the cell surface glycoprotein
Externí odkaz:
https://doaj.org/article/d5c5ca99a1c0441b847786a473f5db05
Autor:
Ozlen Balcioglu, Richard E. Heinz, David W. Freeman, Brooke L. Gates, Berhane M. Hagos, Evan Booker, Elnaz Mirzaei Mehrabad, Hyrum T. Diesen, Kishan Bhakta, Supraja Ranganathan, Masami Kachi, Mathias Leblanc, Peter C. Gray, Benjamin T. Spike
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4L75A-Fc, and showed that it causes loss of the stem cell phenotype in normal mammary epithelia
Externí odkaz:
https://doaj.org/article/c3087deb5d704acbbb79917f2e2e47ce
Autor:
Krista M. Cosert, Soohyun Kim, Iman Jalilian, Maggie Chang, Brooke L. Gates, Kent E. Pinkerton, Laura S. Van Winkle, Vijay Krishna Raghunathan, Brian C. Leonard, Sara M. Thomasy
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 981 (2022)
The ocular surface, comprised of the transparent cornea, conjunctiva, and protective tear film, forms a protective barrier defending deeper structures of the eye from particulate matter and mechanical trauma. This barrier is routinely exposed to a mu
Externí odkaz:
https://doaj.org/article/46c94d48a54d460e80074aa7cbc0974b
Autor:
Ozlen Balcioglu, Brooke L. Gates, David W. Freeman, Berhane M. Hagos, Elnaz Mirzaei Mehrabad, David Ayala-Talavera, Benjamin T. Spike
Breast cancers are categorized into subtypes with distinctive therapeutic vulnerabilities based on expression of clinically targetable receptors and other genes that mimic cell types of the normal gland. Here, we tested the role of the plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa4b6a05b256ba2d587114b29ebfe43
https://doi.org/10.1101/2023.05.10.540211
https://doi.org/10.1101/2023.05.10.540211
Autor:
Atsuhiko Fukuto, Jennifer Kang, Brooke L. Gates, Kimberley Sannajust, Kent E. Pinkerton, Laura S. Van Winkle, Yoshiaki Kiuchi, Brian C. Leonard, Sara M. Thomasy
Publikováno v:
Exp Eye Res
Graphene-based nanomaterials (GBNs) are widely used due to their chemical and physical properties for multiple commercial and environmental applications. From an occupational health perspective, there is concern regarding the effects of inhalation on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a446a67d4b6342931e8a208871f654
https://escholarship.org/uc/item/5dj9x1pm
https://escholarship.org/uc/item/5dj9x1pm
Autor:
Sara M Thomasy, Brian C. Leonard, Maggie W. Chang, Soohyun Kim, Brooke L. Gates, Christopher J. Murphy, Yoshiaki Kiuchi, Laura S. Van Winkle, Atsuhiko Fukuto, Jennifer Kang, Kent E. Pinkerton
Publikováno v:
Translational Vision Science & Technology
Translational vision science & technology, vol 10, iss 12
Translational vision science & technology, vol 10, iss 12
Purpose Corneal keratocyte-fibroblast-myofibroblast (KFM) transformation plays a critical role in corneal stromal wound healing. However, the impact of engineered nanomaterials (ENMs), found in an increasing number of commercial products, on this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3d865ae90fcc66503c3748cd3c7b1a
http://europepmc.org/articles/PMC8525860
http://europepmc.org/articles/PMC8525860
Publikováno v:
Cancer Research. 82:1531-1531
CD146 (Mcam; Muc18; s-endo; and gicerin) is an integral membrane glycoprotein originally identified in a human malignant melanoma, but mis-expressed in a wider variety of malignancies including breast cancer, where it has been implicated in controlli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26a87f2b15b90bf5079914059bff5034
https://doi.org/10.1158/1538-7445.am2022-1531
https://doi.org/10.1158/1538-7445.am2022-1531
Autor:
Jeff Greenland, Thomas A Sasani, Aaron R. Quinlan, Brent S. Pedersen, Brooke L. Gates, Katherine E. Varley, Jordan Swanier, Amelia D. Wallace
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0241253 (2021)
PLoS ONE
PLoS ONE
A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. Long-read sequencing technologies, such as Oxford Nanopore’s MinION
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f694662143e3554de4c0dd5f1c956fc4
https://doaj.org/article/b40febd6e2ea4665b168e7184b3bf972
https://doaj.org/article/b40febd6e2ea4665b168e7184b3bf972
Autor:
Berhane M. Hagos, Brooke L. Gates, David W. Freeman, Masami Kachi, Benjamin T. Spike, Kishan Bhakta, Elnaz Mirzaei Mehrabad, Hyrum T Diesen, Supraja Ranganathan, Mathias Leblanc, Ozlen Balcioglu, Evan Booker, Peter C. Gray, Richard E. Heinz
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Background CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4L75A-Fc, and showed that it causes loss of the stem cell phenotype in normal mammary epithelia suggesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259a122931cac7e4953c13e3f9e16105
https://doi.org/10.1186/s13058-020-01361-z
https://doi.org/10.1186/s13058-020-01361-z