Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brooke E. Shannon"'
Autor:
Bokai Zhu, Brooke E. Shannon, Christina Lee, Ashley L. Wagner, Jeffrey M. Peters, Ellen M. Kehres, Frank J. Gonzalez, Michael G. Borland, Prajakta P. Albrecht
Publikováno v:
Toxicology. :25-32
To examine the functional role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) and PPARγ in skin cancer, stable cell lines were created in the A431 human squamous cell carcinoma cell line. Expression of PPAR target genes was greatly
Autor:
Elizabeth Ola, Christina Lee, Bokai Zhu, Ashley L. Wagner, Boo Hyon Kang, Frank J. Gonzalez, Michael G. Borland, Jeffrey M. Peters, Prajakta P. Albrecht, Pei-Li Yao, Brooke E. Shannon, Ellen M. Kehres, Amanda M. Pritzlaff, Gavin P. Robertson
Publikováno v:
Toxicological Sciences. 159:436-448
Skin tumorigenesis results from DNA damage, increased inflammation, and evasion of apoptosis. The peroxisome proliferator-activated receptors (PPARs) can modulate these mechanisms in non-melanoma skin cancer. However, limited data exists regarding th