Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brooke E Arner"'
Autor:
Fenghua Qian, Shaneice K. Nettleford, Jiayan Zhou, Brooke E. Arner, Molly A. Hall, Arati Sharma, Charyguly Annageldiyev, Randy M. Rossi, Diwakar B. Tukaramrao, Deborpita Sarkar, Shailaja Hegde, Ujjawal H. Gandhi, Emily R. Finch, Laura Goodfield, Michael D. Quickel, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112794- (2023)
Summary: Relapse of acute myeloid leukemia (AML) remains a significant concern due to persistent leukemia-initiating stem cells (LICs) that are typically not targeted by most existing therapies. Using a murine AML model, human AML cell lines, and pat
Externí odkaz:
https://doaj.org/article/ce35a814bf814b97aa20a01a202f9e01
Autor:
Tushar P. Patel, Jordan A. Levine, Diana M. Elizondo, Brooke E. Arner, Arad Jain, Ankit Saxena, Maria Lopez‐Ocasio, Pradeep K. Dagur, Olufisola Famuyiwa, Suryaa Gupta, Zahra Sarrafan‐Chaharsoughi, Angelique Biancotto, J. Philip McCoy, Andrew P. Demidowich, Jack A. Yanovski
Publikováno v:
Obesity. 31:466-478
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde036a4c065c43a23b154d42ed8b4ea
https://doi.org/10.1002/oby.23632
https://doi.org/10.1002/oby.23632
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0689b6133a0f6e7261e754a6738c470a
https://doi.org/10.3791/64834
https://doi.org/10.3791/64834
ObjectiveThere is an unmet need for novel therapies to treat acute myeloid leukemia (AML) and the associated relapse that involves leukemia stem cells (LSCs). An experimental AML rodent model to test therapies based on successfully transplanting thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f2fdb3051961c32520fda164cab083
https://doi.org/10.1101/2022.08.03.502696
https://doi.org/10.1101/2022.08.03.502696
Autor:
Fenghua Qian, Brooke E. Arner, Kathleen M. Kelly, Charyguly Annageldiyev, Arati Sharma, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu
Publikováno v:
FASEB J
Interleukin-4 (IL-4) is a signature cytokine pivotal in Type 2 helper T cell (Th2) immune response, particularly in allergy and hypersensitivity. Interestingly, IL-4 increases endogenous levels of prostaglandin D(2) (PGD(2)) and its metabolites, Δ(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e273f74e5287cb08661cbb150b3b620
https://europepmc.org/articles/PMC9994642/
https://europepmc.org/articles/PMC9994642/
Autor:
Arad Jain, Tushar P Patel, Elizabeth K Altman, Nicol Tugarinov, Noah J Levi, Diana M Elizondo, Brooke E Arner, Robin B Roberson, Alexandre Caron, Joel K Elmquist, Jack A Yanovski
Publikováno v:
Journal of the Endocrine Society. 6:A588-A588
The Melanocortin 3 Receptor (MC3R) is highly expressed in the hypothalamus, where it regulates energy balance and pubertal development. Function-altering SNPs in MC3R have been found to be associated with greater adiposity in both children and adults
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8842e68c797f9961bdfc965b4991e8a9
https://doi.org/10.1210/jendso/bvac150.1218
https://doi.org/10.1210/jendso/bvac150.1218
Autor:
Brooke E Arner, Jordan A Levine, Emily K Miller, Tushar P Patel, Arad Jain, Suryaa Gupta, Robin B Roberson, Andrew P Demidowich, Jack A Yanovski
Publikováno v:
Journal of the Endocrine Society. 6:A2-A2
Health-deteriorating effects of obesity include chronic inflammation and insulin resistance (IR). A recent pilot human trial reported reduced IR in colchicine-treated vs. placebo-treated adults with obesity. Thus, we examined anti-inflammatory and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d25f50806ab8f77bdc05880945bd0a
https://doi.org/10.1210/jendso/bvac150.003
https://doi.org/10.1210/jendso/bvac150.003