Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Brooke E, Wilson"'
Autor:
Brooke E. Wilson, Christopher M. Booth
Publikováno v:
EClinicalMedicine, Vol 78, Iss , Pp 102915- (2024)
Summary: Real-world data (RWD) are rapidly emerging sources of information for patients, clinicians and regulators. While randomized controlled trials (RCTs) reduce bias and confounding through the randomization process and provide the highest qualit
Externí odkaz:
https://doaj.org/article/b17b6fd9beda4951935a69cdb63b69d9
Autor:
Michelle B. Nadler, Brooke E. Wilson, Alexandra Desnoyers, Consolacion Molto Valiente, Ramy R. Saleh, Eitan Amir
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Approval of drugs is based on randomized trials observing statistically significant superiority of an experimental agent over a standard. Statistical significance results from a combination of effect size and sampling, with larger effect siz
Externí odkaz:
https://doaj.org/article/ad2621f4f2e041a0828784637ed92982
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
As indications for immune checkpoint inhibitors for breast cancer continue to expand, rare toxicities will emerge that require careful consideration and multidisciplinary management. We report the case of a 40-year-old female receiving neoadjuvant pe
Externí odkaz:
https://doaj.org/article/21cae8db027d49f18588da0dc8ef28be
Autor:
Michelle B. Nadler, Ann Marie Corrado, Brooke E. Wilson, Alexandra Desnoyers, Eitan Amir, Noah Ivers, Laura Desveaux
Publikováno v:
BMC Women's Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Canadian and US Task Forces recommend against routine mammography screening for women age 40–49 at average breast cancer risk as harms outweigh benefits. Both suggest individualized decisions based on the relative value women pl
Externí odkaz:
https://doaj.org/article/974b1ba604e4489eb02ed66b2503465c
Autor:
Brooke E. Wilson, Richard Sullivan, Richard Peto, Bello Abubakar, Christopher Booth, Gustavo Werutsky, Cary Adams, Agnes Saint-Raymond, Thomas R. Fleming, Kim Lyerly, Julie R. Gralow
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
Rapidly expanding systemic treatment options, combined with improved screening, diagnostic, surgical, and radiotherapy techniques, have led to improved survival outcomes for many cancers over time. However, these overall survival gains have dispropor
Externí odkaz:
https://doaj.org/article/a444ea993fd74de8be9391dd44ba8022
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Background Economic analyses based on clinical trial data are costly and time consuming, and alternative methods for performing economic analyses should be explored.Objective and methods In this perspective, we examine the emerging role of administra
Externí odkaz:
https://doaj.org/article/075a70ab9780428ea680e9e259087a7f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Disease-free survival (DFS) comprises both breast cancer and non-breast cancer events. DFS has not been validated as a surrogate endpoint for overall survival (OS) in most breast cancer subtypes. We assessed changes to the type of events con
Externí odkaz:
https://doaj.org/article/53f8d1a009264e47a7bfc96b3408925c
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Triple negative breast cancer (TNBC) has poor prognosis when compared to other breast cancer subtypes. Despite pre-clinical data supporting an immune targeted approach for TNBCs, immunotherapy has failed to demonstrate the impressive responses seen i
Externí odkaz:
https://doaj.org/article/3732e2ef3e5e4c62bae60e82491369e7
Autor:
Lillian Sung, Danielle Rodin, Rouhi Fazelzad, Vanessa F Bratti, Brooke E Wilson, Aliyah Pabani, Shalini J Zurn, Sonali Johnson
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Introduction Antimicrobial resistance (AMR) is a growing global public health concern and is becoming a significant challenge in the management of patients with cancer. Due to the immunosuppressive nature of cancer treatment, infection is a common co
Externí odkaz:
https://doaj.org/article/c2c01273610849fcb177b711dc458d5d
Autor:
Brooke E. Wilson, Susannah Jacob, Viet Do, Eitan Amir, Freddie Bray, Jacques Ferlay, Felicia M. Knaul, Ahmed Elawawy, Sallie-Anne Pearson, Michael B. Barton
Publikováno v:
JCO Global Oncology, Vol , Iss 7, Pp 1074-1083 (2021)
PURPOSEResource-stratified guidelines (RSG) for cancer provide a hierarchy of interventions, based on resource availability. We quantify treatment need and cost if National Comprehensive Cancer Network (NCCN) RSGs for breast cancer (BC) are adopted g
Externí odkaz:
https://doaj.org/article/a319e61dd8de4ed38004476e41280a3b