Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Brooke E, Chambers"'
Autor:
Sarah E. Lammers, Gabrielle L. Schnellman, Claudia Beimel, Arthur de Gast, Brooke E. Chambers
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Introduction Selecting the optimal radial head prosthesis to treat radial head fractures, especially in the context of complex elbow injuries like terrible triad, Monteggia, and Essex Lopresti, can be challenging, as there is currently no co
Externí odkaz:
https://doaj.org/article/878e1a27a0914303aaad4cc625f0c4b3
Publikováno v:
Journal of Developmental Biology, Vol 11, Iss 1, p 14 (2023)
Nephrons are the functional units which comprise the kidney. Each nephron contains a number of physiologically unique populations of specialized epithelial cells that are organized into discrete domains known as segments. The principles of nephron se
Externí odkaz:
https://doaj.org/article/f2a5a70c995d414bbda945c9d9596f81
Publikováno v:
Cells, Vol 12, Iss 4, p 549 (2023)
A kidney organoid is a three-dimensional (3D) cellular aggregate grown from stem cells in vitro that undergoes self-organization, recapitulating aspects of normal renal development to produce nephron structures that resemble the native kidney organ.
Externí odkaz:
https://doaj.org/article/4d26dc04ad9840fb9e782e99264e02ec
Autor:
Bridgette E. Drummond, Brooke E. Chambers, Hannah M. Wesselman, Shannon Gibson, Liana Arceri, Marisa N. Ulrich, Gary F. Gerlach, Paul T. Kroeger, Ignaty Leshchiner, Wolfram Goessling, Rebecca A. Wingert
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2868 (2022)
Knowledge about the genetic pathways that control nephron development is essential for better understanding the basis of congenital malformations of the kidney. The transcription factors Osr1 and Hand2 are known to exert antagonistic influences to ba
Externí odkaz:
https://doaj.org/article/21f076e41f064964b6333c2c482daa01
Autor:
Brooke E. Chambers, Nicole E. Weaver, Caroline M. Lara, Thanh Khoa Nguyen, Rebecca A. Wingert
Publikováno v:
Tissue Barriers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31d1af009d733cecf13dfe2cfad0b40c
https://doi.org/10.1080/21688370.2023.2219605
https://doi.org/10.1080/21688370.2023.2219605
Autor:
Rebecca A. Wingert, Brooke E. Chambers
Publikováno v:
Kidney International. 96:272-275
Glomerular damage is a harbinger of kidney dysfunction. Circulating permeability factors are implicated in causing primary and secondary damage to podocytes, leading to proteinuria and eventual progression to the nephrotic syndrome, but the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7094eb3d29cac0932245a66c4c1b7c59
https://doi.org/10.1016/j.kint.2019.04.041
https://doi.org/10.1016/j.kint.2019.04.041
Autor:
Bridgette E. Drummond, Rebecca A. Wingert, Marisa Ulrich, Wolfram Goessling, Brooke E. Chambers, Hannah M. Wesselman, Gary F. Gerlach, Ignaty Leshchiner, Paul T. Kroeger
Knowledge about the genetic pathways that control renal cell lineage development is essential to better understand the basis of congenital malformations of the kidney and design regenerative medicine therapies. The embryonic zebrafish kidney, or pron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0b1576234e2539d0c509857d97c97c
https://doi.org/10.1101/2020.12.21.423845
https://doi.org/10.1101/2020.12.21.423845
Publikováno v:
Development
A functional vertebrate kidney relies on structural units called nephrons, which are epithelial tubules that contain a sequence of segments each expressing a distinct repertoire of solute transporters. To date, the transcriptional codes driving regio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc23cdffa8ca1a21c6e3ffe91a5304d4
https://pubmed.ncbi.nlm.nih.gov/33028614
https://pubmed.ncbi.nlm.nih.gov/33028614
Autor:
Amanda N, Marra, Brooke E, Chambers, Joseph M, Chambers, Bridgette E, Drummond, Basma D, Adeeb, Hannah M, Wesselman, Elvin E, Morales, Nicole, Handa, Tom, Pettini, Matthew, Ronshaugen, Rebecca A, Wingert
Publikováno v:
Methods in cell biology. 154
The vertebrate kidney is comprised of functional units known as nephrons. Defects in nephron development or activity are a common feature of kidney disease. Current medical treatments are unable to ameliorate the dire consequences of nephron deficit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43ccdae03b27912a7dd67d11c790ef33
https://pubmed.ncbi.nlm.nih.gov/31493818
https://pubmed.ncbi.nlm.nih.gov/31493818
Autor:
Meghan Springer, Marisa Ulrich, Rebecca A. Wingert, Amanda N. Marra, Amanda Addiego, Shahram Jevin Poureetezadi, Matthew Ronshaugen, Joseph M. Chambers, Basma D. Adeeb, Brooke E. Chambers, Bridgette E. Drummond
Publikováno v:
Marra, A N, Adeeb, B D, Chambers, B E, Drummond, B E, Ulrich, M, Addiego, A, Springer, M, Poureetezadi, S J, Chambers, J M, Ronshaugen, M & Wingert, R A 2019, ' Prostaglandin signaling regulates renal multiciliated cell specification and maturation ', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 17, pp. 8409-8418 . https://doi.org/10.1073/pnas.1813492116
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Multiciliated cells (MCCs) have core roles in organ formation and function, where they control fluid flow and particle displacement. MCCs direct fluid movement in the brain and spinal cord, clearance of respiratory mucus, and ovum transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ba10222e0970dfa1482c8b7e4ff24
https://doi.org/10.1073/pnas.1813492116
https://doi.org/10.1073/pnas.1813492116