Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3.

Autor: Hind C; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Clifford M; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Woolley C; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Harmer J; School of Applied Sciences, University of Huddersfield, Queensgate, HuddersfieldHD1 3DH, United Kingdom., McGee LMC; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Tyson-Hirst I; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Tait HJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Brooke DP; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Dancer SJ; Department of Microbiology, Hairmyres Hospital, NHS Lanarkshire, GlasgowG75 8RG, United Kingdom.; School of Applied Sciences, Edinburgh Napier University, EdinburghEH11 4BN, United Kingdom., Hunter IS; Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, GlasgowG4 0RE, United Kingdom., Suckling CJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Beveridge R; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Parkinson JA; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Sutton JM; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom.; Institute of Pharmaceutical Science, School of Cancer & Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, LondonSE1 9NH, United Kingdom., Scott FJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2022 Dec 09; Vol. 8 (12), pp. 2552-2563. Date of Electronic Publication: 2022 Nov 29.

Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype.

Autor: Brooke DP; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., McGee LMC; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Giordani F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow Glasgow UK., Cross JM; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Khalaf AI; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Irving C; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Gillingwater K; Parasite Chemotherapy Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute Basel Switzerland.; University of Basel Basel Switzerland., Shaw CD; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde Glasgow UK., Carter KC; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde Glasgow UK., Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow Glasgow UK., Suckling CJ; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Scott FJ; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2021 Jul 06; Vol. 12 (8), pp. 1391-1401. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).