Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3.

Autor: Hind C; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Clifford M; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Woolley C; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom., Harmer J; School of Applied Sciences, University of Huddersfield, Queensgate, HuddersfieldHD1 3DH, United Kingdom., McGee LMC; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Tyson-Hirst I; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Tait HJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Brooke DP; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Dancer SJ; Department of Microbiology, Hairmyres Hospital, NHS Lanarkshire, GlasgowG75 8RG, United Kingdom.; School of Applied Sciences, Edinburgh Napier University, EdinburghEH11 4BN, United Kingdom., Hunter IS; Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, GlasgowG4 0RE, United Kingdom., Suckling CJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Beveridge R; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Parkinson JA; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom., Sutton JM; Research and Evaluation, UKHSA Porton Down, SalisburySP4 0JG, United Kingdom.; Institute of Pharmaceutical Science, School of Cancer & Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, LondonSE1 9NH, United Kingdom., Scott FJ; Department of Pure and Applied Chemistry, University of Strathclyde, GlasgowG1 1XL, United Kingdom.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2022 Dec 09; Vol. 8 (12), pp. 2552-2563. Date of Electronic Publication: 2022 Nov 29.

Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype.

Autor: Brooke DP; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., McGee LMC; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Giordani F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow Glasgow UK., Cross JM; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Khalaf AI; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Irving C; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Gillingwater K; Parasite Chemotherapy Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute Basel Switzerland.; University of Basel Basel Switzerland., Shaw CD; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde Glasgow UK., Carter KC; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde Glasgow UK., Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation and Glasgow Polyomics, College of Medical, Veterinary and Life Sciences, University of Glasgow Glasgow UK., Suckling CJ; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk., Scott FJ; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde Glasgow UK fraser.j.scott@strath.ac.uk.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2021 Jul 06; Vol. 12 (8), pp. 1391-1401. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).

Brucellosis: A Zoonotic Disease

Autor: H Rahman, Rajeswari Shome, M Nagalingam

Brucellosis is one of the world's major zoonoses that still are of animal health, public health and economic concern in many parts of the world. In addition to its significant zoonotic impact on human health, brucellosis in livestock is of considerab