Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Brooke Bentley"'
Autor:
Kelly J Gauger, Lotfi M Bassa, Elizabeth M Henchey, Josephine Wyman, Brooke Bentley, Melissa Brown, Akihiko Shimono, Sallie S Schneider
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e78320 (2013)
The molecular mechanisms involved in the development of obesity and related complications remain unclear. Wnt signaling plays an important role in preadipocyte differentiation and adipogenesis. The expression of a Wnt antagonist, secreted frizzled re
Externí odkaz:
https://doaj.org/article/36e281cdb9be479ba04211e181ea856b
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25819 (2011)
We previously reported that a secreted glycoprotein YKL-40 acts as an angiogenic factor to promote breast cancer angiogenesis. However, its functional role in normal mammary gland development is poorly understood. Here we investigated its biophysiolo
Externí odkaz:
https://doaj.org/article/cd3d63629ad04e9ab14e677aeb6f1eb0
Supplementary Figure 2 from A YKL-40–Neutralizing Antibody Blocks Tumor Angiogenesis and Progression: A Potential Therapeutic Agent in Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b5fcb9058a6c5cdff41fc6627d7e83
https://doi.org/10.1158/1535-7163.22497015.v1
https://doi.org/10.1158/1535-7163.22497015.v1
Supplementary Figure 1 from A YKL-40–Neutralizing Antibody Blocks Tumor Angiogenesis and Progression: A Potential Therapeutic Agent in Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b647ff07e22e1b142add0a083df2712
https://doi.org/10.1158/1535-7163.22497018.v1
https://doi.org/10.1158/1535-7163.22497018.v1
Accumulating evidence has indicated that expression levels of YKL-40, a secreted glycoprotein, were elevated in multiple advanced human cancers. Recently, we have identified an angiogenic role of YKL-40 in cancer development. However, blockade of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea79cb545dee1f96346f936c0a7af84
https://doi.org/10.1158/1535-7163.c.6535470
https://doi.org/10.1158/1535-7163.c.6535470
Autor:
Cameron Pearson, Chase Redd, Amy M. Buddie, Lora Asberry, Anjie Ashley Adeyemo, Brooke Bentley, Sharon M. Pearcey, Jeavanie Desarmes, Giovanni Still, Shaharazad Muhammad, Margot Aldana, Abeer Osman
Publikováno v:
Journal of Student Research.
Research has shown that science-related majors who are exposed to information pertaining to their general and physical health have a better understanding of what is needed for a healthy lifestyle compared to their counterparts in majors outside of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55f96bcc4e291b6fe9c8820e853c85c5
https://doi.org/10.47611/jsr.vi.669
https://doi.org/10.47611/jsr.vi.669
Publikováno v:
Oncogene
Tumor neo-vasculature is characterized by spatial coordination of endothelial cells with mural cells, which delivers oxygen and nutrients. Here, we explored a key role of the secreted glycoprotein YKL-40, a mesenchymal marker, in the interaction betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e914f9a20bfcc4b0d02359f062f470e7
https://doi.org/10.1038/onc.2013.160
https://doi.org/10.1038/onc.2013.160
Autor:
Wei Yan, Sherry L. Taylor, Dennis Oh, Brooke Bentley, Robert Schapiro, Luis Moral, Michael Faibish, Steve Scully, Ralph Francescone, Rong Shao
Publikováno v:
The Journal of Neuroscience. 32:12950-12960
Recent evidence has shown that glioblastoma stem-like cells (GSCs) can transdifferentiate into endothelial cells and vascular-like tumor cells. The latter pattern of vascularization indicates an alternative microvascular circulation known as vasculog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a10472d02171fc8af7c185e067e8747
https://doi.org/10.1523/jneurosci.2017-12.2012
https://doi.org/10.1523/jneurosci.2017-12.2012
Autor:
Ralph Francescone, Dennis Oh, Steve Scully, Sherry L. Taylor, Brooke Bentley, Rong Shao, Wei Yan, Luis Moral
Publikováno v:
Journal of Biological Chemistry. 287:24821-24831
Glioblastoma (GBM) is extremely aggressive and essentially incurable. Its malignancy is characterized by vigorous microvascular proliferations. Recent evidence has shown that tumor cells display the ability to drive blood-perfused vasculogenic mimicr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2c6c60d403f41b4839c347ad51b4e1
https://doi.org/10.1074/jbc.m111.334540
https://doi.org/10.1074/jbc.m111.334540
Publikováno v:
British Journal of Cancer
Background: Serum levels of a secreted glycoprotein YKL-40 are elevated in patients with a wide range of cancers including breast, colorectal, and ovarian cancers. Furthermore, these increased levels correlate with poorer survival of cancer patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f218658c5aa6d45c4928bcf0206b06f
https://doi.org/10.1038/bjc.2011.347
https://doi.org/10.1038/bjc.2011.347