Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brooke A Miskie"'
Autor:
Robert A. Hegele, Jane Yuan, Jelena Vukmirica, Khai Tran, Marilyn D. Resh, Zemin Yao, Brooke A Miskie, Jing Shan, Xiquan Liang
Publikováno v:
Journal of Biological Chemistry. 278:14153-14161
We examined the role of S-linked palmitoylation of human apolipoprotein (apo) B in the assembly and secretion of very low density lipoproteins using recombinant human apoB48. There are four free cysteine residues (Cys(1085), Cys(1396), Cys(1478), and
Autor:
Jing Shan, Khai Tran, C. James McKnight, Robert A. Hegele, A.J. Whitfield, Zemin Yao, Brooke A Miskie, John R. Burnett, Jane Yuan
Publikováno v:
Journal of Biological Chemistry. 278:13442-13452
Familial hypobetalipoproteinemia (FHBL), an autosomal co-dominant disorder, is associated with reduced plasma concentrations (5th percentile for age and sex) of apolipoprotein (apo) B and beta-migrating lipoproteins. To date, only mutations in APOB e
Publikováno v:
Robarts Vascular Research Publications
Lipids in Health and Disease
Lipids in Health and Disease, Vol 6, Iss 1, p 7 (2007)
Lipids in Health and Disease
Lipids in Health and Disease, Vol 6, Iss 1, p 7 (2007)
Background Statin-related skeletal muscle disorders range from benign myalgias – such as non-specific muscle aches or joint pains without elevated serum creatinine kinase (CK) concentration – to true myositis with >10-fold elevation of serum CK,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99abfd1273518e68651b1d0f3bfb98c
https://ir.lib.uwo.ca/vascularpub/9
https://ir.lib.uwo.ca/vascularpub/9
Autor:
Brian K. Rutt, John F. Robinson, Rhonda Walcarius, Rebecca L. Pollex, Salam A. Al-Attar, Brooke A Miskie, Robert A. Hegele
Publikováno v:
BMC Medical Imaging
BMC Medical Imaging, Vol 6, Iss 1, p 11 (2006)
Robarts Vascular Research Publications
BMC Medical Imaging, Vol 6, Iss 1, p 11 (2006)
Robarts Vascular Research Publications
Background With the growing prevalence of obesity and metabolic syndrome, reliable quantitative imaging methods for adipose tissue are required. Monogenic forms of the metabolic syndrome include Dunnigan-variety familial partial lipodystrophy subtype
Publikováno v:
Lipids in Health and Disease, Vol 4, Iss 1, p 26 (2005)
Lipids in Health and Disease
Department of Medicine Publications
Lipids in Health and Disease
Department of Medicine Publications
Background Cholesterol ester storage disease (CESD) is an autosomal recessive illness that results from mutations in the LIPA gene encoding lysosomal acid lipase. CESD patients present in childhood with hepatomegaly and dyslipidemia characterized by
Autor:
Brooke A Miskie, Robert A. Hegele, John F. Robinson, David E. Carter, James McKinney, Jian Wang, Hafiz M. R. Khan
Publikováno v:
Clinical biochemistry. 37(9)
Objectives: Microarray analysis of gene expression profiles of blood leukocytes has many potential clinical and research applications. Design and methods: We used the PAXgene Blood RNA System to prepare RNA from the whole blood of normal volunteers u
Autor:
Jelena, Vukmirica, Khai, Tran, Xiquan, Liang, Jing, Shan, Jane, Yuan, Brooke A, Miskie, Robert A, Hegele, Marilyn D, Resh, Zemin, Yao
Publikováno v:
The Journal of biological chemistry. 278(16)
We examined the role of S-linked palmitoylation of human apolipoprotein (apo) B in the assembly and secretion of very low density lipoproteins using recombinant human apoB48. There are four free cysteine residues (Cys(1085), Cys(1396), Cys(1478), and
Publikováno v:
Journal of human genetics. 47(9)
We report the identification of a loss-of-function -11C>T promoter mutation in the gene encoding the sterol regulatory element binding protein cleavage-activating protein (SCAP). The -11T allele was associated with a marked reduction in promoter acti
Publikováno v:
Journal of human genetics. 46(12)
The proprotein convertase. subtilisin/kexin type 5, or PCSK5, mediates post-translational endoproteolytic processing for several integrin alpha subunits. We identified two silent single-nucleotide polymorphisms (SNPs) in PCSK5, which were found to va
Publikováno v:
Annals of Internal Medicine. 138:77