Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Brooke A Marks"'
Autor:
Sachi Horibata, Edward J Rice, Hui Zheng, Chinatsu Mukai, Tinyi Chu, Brooke A Marks, Scott A Coonrod, Charles G Danko
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194522 (2018)
Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for end
Externí odkaz:
https://doaj.org/article/18ccffbc827744b1b08c5ada6c81555e
Autor:
Sachi Horibata, Edward J Rice, Chinatsu Mukai, Brooke A Marks, Kelly Sams, Hui Zheng, Lynne J Anguish, Scott A Coonrod, Charles G Danko
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194023 (2018)
The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However, we know little about how ER+ cells activate RET signaling and initiate an endocrine resistant phenotype. Here we show that bot
Externí odkaz:
https://doaj.org/article/f0cbcbf30bee4fb8adfff12a7990424a
Autor:
Brooke A. Marks, Ilissa M. Pipia, Chinatsu Mukai, Sachi Horibata, Edward J. Rice, Charles G. Danko, Scott A. Coonrod
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by which this signaling cascade promotes resistance is currently not well de
Externí odkaz:
https://doaj.org/article/a513dee986ef4a7189c12bc44866baf1
Autor:
Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks, Chitvan Mittal, Elena Alina Demeter, Sophie Nelissen, Jennifer K. Grenier, Ann E. Tate, Faraz Ahmed, Scott A. Coonrod
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Peptidylarginine deiminase enzymes (PADs) convert arginine residues to citrulline in a process called citrullination or deimination. Recently, two PADs, PAD2 and PAD4, have been linked to hormone signaling in vitro and the goal of
Externí odkaz:
https://doaj.org/article/2bdd95194a7f4186a8fd4b000a5e765e
Autor:
Brooke A. Marks, Lauren A. Choate, Kelly Sams, Lina Zhu, Gavisha Waidyaratne, Charles G. Danko, Scott A. Coonrod
Resistance to endocrine therapy is a common problem in patients with estrogen receptor alpha (ERα) positive breast cancer. In this study, we took a non-biased genome-wide approach to identify novel mechanisms of endocrine resistance using a clustere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d60527f02279a79857c304d83230785
https://doi.org/10.1101/2022.08.22.504845
https://doi.org/10.1101/2022.08.22.504845
Autor:
Lauren A. Choate, Kelly L. Sams, Lynne J. Anguish, Scott A. Coonrod, Yukinari Kato, Elena Zu Klampen, Brooke A. Marks, Andrew D. Miller, Zhong Wang, Chinatsu Mukai, Edward J. Rice, Charles G. Danko, Shao-Pei Chou, Eunju Choi
Publikováno v:
BMC Veterinary Research
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-14 (2020)
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-14 (2020)
Background Canine visceral hemangiosarcoma (HSA) is a highly aggressive cancer of endothelial origin that closely resembles visceral angiosarcoma in humans, both clinically and histopathologically. Currently there is an unmet need for new diagnostics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35eec6366bf08f5285e83662d743b5c
https://doi.org/10.21203/rs.2.20379/v2
https://doi.org/10.21203/rs.2.20379/v2
Autor:
Adam Siepel, Elia D. Tait Wojno, Tinyi Chu, W. Lee Kraus, John T. Lis, Noah Dukler, Charles G. Danko, Zhong Wang, André L. Martins, Scott A. Coonrod, Lauren A. Choate, Brooke A. Marks, Edward J. Rice
Publikováno v:
Nature Ecology & Evolution. 2:537-548
How evolutionary changes at enhancers affect the transcription of target genes remains an important open question. Previous comparative studies of gene expression have largely measured the abundance of messenger RNA, which is affected by post-transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6096d73db22ced515334e741479adc4d
https://doi.org/10.1038/s41559-017-0447-5
https://doi.org/10.1038/s41559-017-0447-5
Autor:
Charles G, Danko, Lauren A, Choate, Brooke A, Marks, Edward J, Rice, Zhong, Wang, Tinyi, Chu, Andre L, Martins, Noah, Dukler, Scott A, Coonrod, Elia D, Tait Wojno, John T, Lis, W Lee, Kraus, Adam, Siepel
Publikováno v:
Nature ecologyevolution. 2(3)
How evolutionary changes at enhancers affect the transcription of target genes remains an important open question. Previous comparative studies of gene expression have largely measured the abundance of messenger RNA, which is affected by post-transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a67c6f7ea31a180c06e40f724c2403b
https://pubmed.ncbi.nlm.nih.gov/29379186
https://pubmed.ncbi.nlm.nih.gov/29379186
Publikováno v:
Protein Deimination in Human Health and Disease ISBN: 9783319582436
Peptidylarginine deiminases (PADs or PADIs) are a family of calcium-dependent enzymes that post-translationally convert positively charged arginine residues to neutrally charged citrulline in a process called citrullination or deimination. There are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30adfaa1bbc2a34aa6fe8befdf00285
https://doi.org/10.1007/978-3-319-58244-3_4
https://doi.org/10.1007/978-3-319-58244-3_4
Autor:
Wojno Edt, John T. Lis, Adam Siepel, Tinyi Chu, W. Lee Kraus, Noah Dukler, Brooke A. Marks, Lauren A. Choate, Edward J. Rice, André L. Martins, Charles G. Danko, Scott A. Coonrod, Zhong Wang
Transcriptional regulatory changes have been shown to contribute to phenotypic differences between species, but many questions remain about how gene expression evolves. Here we report the first comparative study of nascent transcription in primates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8ff8d238f877fd4358aa190cdec5a
https://doi.org/10.1101/083212
https://doi.org/10.1101/083212