Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Brooke, Fehily"'
Autor:
Ryan L. O’Hare Doig, Sreya Santhakumar, Brooke Fehily, Sushmitha Raja, Tanya Solomon, Carole A. Bartlett, Melinda Fitzgerald, Stuart I. Hodgetts
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Reducing the extent of secondary degeneration following spinal cord injury (SCI) is necessary to preserve function, but treatment options have thus far been limited. A combination of the ion channel inhibitors Lomerizine (Lom), YM872 and oxATP, to in
Externí odkaz:
https://doaj.org/article/14d6a50030fe4f2fbbe32f497cbe1789
Autor:
Stuart I. Hodgetts, Jun Han Yoon, Alysia Fogliani, Emmanuel A. Akinpelu, Danii Baron-Heeris, Imke G. J. Houwers, Lachlan P. G. Wheeler, Bernadette T. Majda, Sreya Santhakumar, Sarah J. Lovett, Emma Duce, Margaret A. Pollett, Tylie M. Wiseman, Brooke Fehily, Alan R. Harvey
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the ce
Externí odkaz:
https://doaj.org/article/1a8b0e65624940cbb9fcbfda79c855ba
Autor:
Brooke Fehily, Melinda Fitzgerald
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern, accounting for the majority of all head injuries. While symptoms are generally transient, some patients go on to experience long-term cognitive impairments and add
Externí odkaz:
https://doaj.org/article/100702d3b8754f639ca07cf476a3a917
Autor:
Jan M. Hemmi, Hannah R. Milbourn, Stephen Lydiard, Maimuna Majimbi, Melinda Fitzgerald, Sarah A. Dunlop, Michael Archer, Carole A. Bartlett, Nathanael J. Yates, Brooke Fehily
Publikováno v:
Journal of Neurochemistry. 149:660-678
Following mild traumatic brain injury (mTBI), further mild impacts can exacerbate negative outcomes. To compare chronic damage and deficits following increasing numbers of repeated mTBIs, a closed-head weight-drop model of repeated mTBI was used to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9dc7c1f61c3aedfbe6ecbaf8da612f
https://doi.org/10.1111/jnc.14673
https://doi.org/10.1111/jnc.14673
Autor:
Gillian Weir, Nathanael J. Yates, Melinda Fitzgerald, Stephen Lydiard, Aaron Chin, Carole A. Bartlett, Brooke Fehily, Jacqueline Alderson
Publikováno v:
Experimental Brain Research. 235:2133-2149
Negative outcomes of mild traumatic brain injury (mTBI) can be exacerbated by repeated insult. Animal models of repeated closed-head mTBI provide the opportunity to define acute pathological mechanisms as the number of mTBI increases. Furthermore, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5ff06267334f6d453db4e7c91386d5
https://doi.org/10.1007/s00221-017-4958-8
https://doi.org/10.1007/s00221-017-4958-8
Autor:
Melinda Fitzgerald, Ryu Takechi, Samra Krakonja, Hannah R. Milbourn, Michael Nesbit, Brooke Fehily, Anna M. B. Black, Carole A. Bartlett, Nathanael J. Yates, Yilin Mao
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3408 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences
Volume 19
Issue 11
Following mild traumatic brain injury (mTBI), the ionic homeostasis of the central nervous system (CNS) becomes imbalanced. Excess Ca2+ influx into cells triggers molecular cascades, which result in detrimental effects. The authors assessed the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7caaefeb79d568da4294c1c6e7dd559
https://www.mdpi.com/1422-0067/19/11/3408
https://www.mdpi.com/1422-0067/19/11/3408
Autor:
Alysia Fogliani, Imke G. J. Houwers, Lachlan P.G. Wheeler, Jun Han Yoon, Danii Baron-Heeris, Emmanuel A. Akinpelu, Emma Duce, Bernadette T. Majda, Sreya Santhakumar, Tylie M. Wiseman, Alan R. Harvey, Sarah J. Lovett, Brooke Fehily, Stuart I. Hodgetts, Margaret A. Pollett
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d23e6ba33a3df602fb854de36c14706
https://doaj.org/article/1a8b0e65624940cbb9fcbfda79c855ba
https://doaj.org/article/1a8b0e65624940cbb9fcbfda79c855ba
Autor:
Melinda Fitzgerald, Brooke Fehily
Publikováno v:
Cell Transplantation
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern, accounting for the majority of all head injuries. While symptoms are generally transient, some patients go on to experience long-term cognitive impairments and add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3de88294bed824ef794514734a6ba3
https://pubmed.ncbi.nlm.nih.gov/28933213
https://pubmed.ncbi.nlm.nih.gov/28933213
Autor:
Hannah R, Milbourn, Lillian M, Toomey, Nikolas, Gavriel, Chloe G G, Gray, Alexander H, Gough, Brooke, Fehily, Marcus K, Giacci, Melinda, Fitzgerald
Publikováno v:
Discovery medicine. 23(129)
Following injury to the central nervous system, secondary degeneration is mediated by Ca2+ imbalances and overproduction of reactive oxygen species from mitochondria, and is associated with myelin deficits and loss of function. Preventing intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04933786df4e88e3fd575602027acb75
https://pubmed.ncbi.nlm.nih.gov/28877447
https://pubmed.ncbi.nlm.nih.gov/28877447
Autor:
Hr, Milbourn, Lm, Toomey, Gavriel N, Cgg, Gray, Ah, Gough, Brooke Fehily, Mk, Giacci, Fitzgerald M
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5eee5be93aecceb1df900235ebf2945b
http://europepmc.org/abstract/med/28877447
http://europepmc.org/abstract/med/28877447
