Targeting neuroinflammation in Alzheimer’s disease

Autor: Bronzuoli MR, Iacomino A, Steardo L, Scuderi C

Publikováno v: Journal of Inflammation Research, Vol Volume 9, Pp 199-208 (2016)

Maria Rosanna Bronzuoli,1 Aniello Iacomino,2 Luca Steardo,1 Caterina Scuderi1 1Department of Physiology and Pharmacology “Vittorio Erspamer”, Sapienza University of Rome, Rome, Italy; 2Faculty of Psychology, University of Rome “G. Marconi”, R

Externí odkaz: https://doaj.org/article/966a28324cd842ec8cf572845128efa6

Molecular signatures of astrocytes and microglia maladaptive responses to acute stress are rescued by a single administration of ketamine in a rodent model of PTSD.

Autor: Valenza M; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy., Facchinetti R; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy., Torazza C; Department of Pharmacy, Unit of Pharmacology and Toxicology, University of Genoa, Genoa, Italy., Ciarla C; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy., Bronzuoli MR; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy., Balbi M; Department of Pharmacy, Unit of Pharmacology and Toxicology, University of Genoa, Genoa, Italy., Bonanno G; Department of Pharmacy, Unit of Pharmacology and Toxicology, University of Genoa, Genoa, Italy., Popoli M; Dipartimento di Scienze Farmaceutiche, Università Degli Studi di Milano, Milano, Italy., Steardo L; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy., Milanese M; Department of Pharmacy, Unit of Pharmacology and Toxicology, University of Genoa, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Musazzi L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Bonifacino T; Department of Pharmacy, Unit of Pharmacology and Toxicology, University of Genoa, Genoa, Italy., Scuderi C; Department of Physiology and Pharmacology 'Vittorio Erspamer', SAPIENZA University of Rome, Rome, Italy. caterina.scuderi@uniroma1.it.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2024 May 25; Vol. 14 (1), pp. 209. Date of Electronic Publication: 2024 May 25.

The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system.

Autor: Maftei D; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Ratano P; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy; Nanotechnology Institute, CNR-Nanotechnology Institute (CNR-NANOTEC), Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Fusco I; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Marconi V; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Squillace S; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Negri L; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Severini C; Institute of Cell Biology and Neurobiology, CNR, Sense organs Department, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, Italy., Balboni G; Department of Life and Environmental Sciences, Unit of Pharmaceutical, Pharmacological and Nutraceutical Sciences, University of Cagliari, Via Ospedale 72, 09124, Cagliari, Italy., Steardo L; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Bronzuoli MR; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Scuderi C; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Campolongo P; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy., Lattanzi R; Department of Physiology and Pharmacology 'Vittorio Erspamer', Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy. Electronic address: roberta.lattanzi@uniroma1.it.

Publikováno v: Neuropharmacology [Neuropharmacology] 2019 Nov 01; Vol. 158, pp. 107739. Date of Electronic Publication: 2019 Aug 10.

Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease.

Autor: Cassano T; Department of Clinical and Experimental Medicine, Medical School, University of Foggia, 71100 Foggia, Italy. Electronic address: tommaso.cassano@unifg.it., Magini A; Department of Chemistry, Biology and Biotechnology, University of Perugia, 06126 Perugia, Italy., Giovagnoli S; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy., Polchi A; Department of Chemistry, Biology and Biotechnology, University of Perugia, 06126 Perugia, Italy., Calcagnini S; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., Pace L; Department of Clinical and Experimental Medicine, Medical School, University of Foggia, 71100 Foggia, Italy., Lavecchia MA; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., Scuderi C; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., Bronzuoli MR; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., Ruggeri L; Division of Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, 06132 Perugia, Italy., Gentileschi MP; UOSD SAFU, RiDAIT Dept, The Regina Elena National Cancer Institute, 00144 Rome, Italy., Romano A; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., Gaetani S; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, 00185 Rome, Italy., De Marco F; UOSD SAFU, RiDAIT Dept, The Regina Elena National Cancer Institute, 00144 Rome, Italy., Emiliani C; Department of Chemistry, Biology and Biotechnology, University of Perugia, 06126 Perugia, Italy., Dolcetta D; UOSD SAFU, RiDAIT Dept, The Regina Elena National Cancer Institute, 00144 Rome, Italy. Electronic address: diego.dolcetta@gmail.com.

Publikováno v: Experimental neurology [Exp Neurol] 2019 Jan; Vol. 311, pp. 88-105. Date of Electronic Publication: 2018 Sep 20.

Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders.

Autor: Cartocci V; Department of Science, Section of Biomedical Sciences and Technologies, University 'Roma Tre', Viale Marconi 446, 00146 Rome, Italy., Catallo M; Department of Science, Section of Biomedical Sciences and Technologies, University 'Roma Tre', Viale Marconi 446, 00146 Rome, Italy., Tempestilli M; National Institute for Infectious Diseases, Via Portuense 292, 00149 Rome, Italy., Segatto M; Department of Biosciences, University of Milan, Via Giovanni Celoria, 26, 20133 Milan, Italy., Pfrieger FW; Institute of Cellular and Integrative Neurosciences CNRS UPR 3212 University of Strasbourg, 5 rue Blaise Pascal, 67084 Strasbourg, France., Bronzuoli MR; Department of Physiology and Pharmacology 'Vittorio Erspamer' SAPIENZA University of Rome, Piazzale A. Moro 5 00185 Rome, Italy., Scuderi C; Department of Physiology and Pharmacology 'Vittorio Erspamer' SAPIENZA University of Rome, Piazzale A. Moro 5 00185 Rome, Italy., Servadio M; Department of Science, Section of Biomedical Sciences and Technologies, University 'Roma Tre', Viale Marconi 446, 00146 Rome, Italy., Trezza V; Department of Science, Section of Biomedical Sciences and Technologies, University 'Roma Tre', Viale Marconi 446, 00146 Rome, Italy., Pallottini V; Department of Science, Section of Biomedical Sciences and Technologies, University 'Roma Tre', Viale Marconi 446, 00146 Rome, Italy. Electronic address: valentina.pallottini@uniroma3.it.

Publikováno v: Neuroscience [Neuroscience] 2018 Feb 21; Vol. 372, pp. 27-37. Date of Electronic Publication: 2018 Jan 06.