Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bronwyn E. Brown"'
Autor:
Nadim eNaser, Andrzej S. Januszewski, Bronwyn E. Brown, Alicia J. Jenkins, Michael A Hill, Timothy V Murphy
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
Post-translational modification of proteins in diabetes, including formation of advanced glycation end products (AGEs) are believed to contribute to vascular dysfunction and disease. Impaired function of the endothelium is an early indicator of vascu
Externí odkaz:
https://doaj.org/article/bbc2556667f14b38af2f9c9b527c4f4f
Autor:
Fahd O Ismael, Tessa J Barrett, Diba Sheipouri, Bronwyn E Brown, Michael J Davies, Clare L Hawkins
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168844 (2016)
Low-density lipoprotein (LDL) is the major source of lipid within atherosclerotic lesions. Myeloperoxidase (MPO) is present in lesions and forms the reactive oxidants hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN). These oxidants modify LD
Externí odkaz:
https://doaj.org/article/5154712134ee493eac4de4dae36a5460
Autor:
Shannon Chiang, Bronwyn E. Brown, Amy Anzovino, Clare L. Hawkins, Michael L.-H. Huang, Des R. Richardson
Publikováno v:
The American Journal of Pathology. 187:2858-2875
Nuclear factor–erythroid 2–related factor-2 (Nrf2) is a master regulator of the antioxidant response. However, studies in models of Friedreich ataxia, a neurodegenerative and cardiodegenerative disease associated with oxidative stress, reported d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a728389b1b811999b96a5c1fbf20147b
https://doi.org/10.1016/j.ajpath.2017.08.021
https://doi.org/10.1016/j.ajpath.2017.08.021
Autor:
Josephine M. Forbes, Sofianos Andrikopoulos, Peter W Angus, Bronwyn E. Brown, Leni R. Rivera, Chandana B Herath, Christopher Leung, Zhiyuan Jia, John B. Furness, Michael J. Davies
Publikováno v:
World Journal of Gastroenterology
AIM: To determine if manipulation of dietary advanced glycation end product (AGE), intake affects non-alcoholic fatty liver disease (NAFLD) progression and whether these effects are mediated via RAGE. METHODS: Male C57Bl6 mice were fed a high fat, hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b33c85f957639cb2529f59848140cc
http://europepmc.org/articles/PMC5028816
http://europepmc.org/articles/PMC5028816
Autor:
Leila Reyes, Victoria C. Cogger, Benjamin S. Rayner, Yunjia Zhang, Bronwyn E. Brown, Clare L. Hawkins
Publikováno v:
Free radical biologymedicine. 129
The infiltration of activated leukocytes, including macrophages, at sites of inflammation and the formation and presence of hypochlorous acid (HOCl) are interlinked hallmarks of many debilitating disease processes, including atherosclerosis, arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0061c346b0f4aa124063ccdbef641a
https://pubmed.ncbi.nlm.nih.gov/30189264
https://pubmed.ncbi.nlm.nih.gov/30189264
Autor:
Fahd Ismael, David M. van Reyk, Kevin D. Croft, Bronwyn E. Brown, Michael J. Davies, Julie M. Proudfoot, Clare L. Hawkins
Publikováno v:
Archives of Biochemistry and Biophysics. 573:40-51
Atherosclerosis is characterised by the accumulation of lipids within macrophages in the artery wall. Low-density lipoprotein (LDL) is the source of this lipid, owing to the uptake of oxidised LDL by scavenger receptors. Myeloperoxidase (MPO) release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d48c44614fcc319bd1cf3e488c56ba7
https://doi.org/10.1016/j.abb.2015.03.008
https://doi.org/10.1016/j.abb.2015.03.008
Autor:
Amy, Anzovino, Shannon, Chiang, Bronwyn E, Brown, Clare L, Hawkins, Des R, Richardson, Michael L-H, Huang
Publikováno v:
The American journal of pathology. 187(12)
Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a master regulator of the antioxidant response. However, studies in models of Friedreich ataxia, a neurodegenerative and cardiodegenerative disease associated with oxidative stress, reported decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38fd27a3d613998d2582efc3775e8a8e
https://pubmed.ncbi.nlm.nih.gov/28935570
https://pubmed.ncbi.nlm.nih.gov/28935570
Autor:
Christina A. Bursill, Christine H.J. Kim, Fraser R. Torpy, Michael J. Davies, David M. van Reyk, Lucinda S. McRobb, Bronwyn E. Brown, Alison K. Heather
Publikováno v:
Atherosclerosis. 232:403-409
Objective Carnosine has been shown to modulate triglyceride and glycation levels in cell and animal systems. In this study we investigated whether prolonged supplementation with carnosine inhibits atherosclerosis and markers of lesion stability in hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad69b3818f965c1f0940abf802f91e0e
https://doi.org/10.1016/j.atherosclerosis.2013.11.068
https://doi.org/10.1016/j.atherosclerosis.2013.11.068
Autor:
Amy Anzovino, Michael L.-H. Huang, Des R. Richardson, Clare L. Hawkins, Shannon Chiang, Bronwyn E. Brown
Publikováno v:
Free Radical Biology and Medicine. 128:S131
Cardiomyopathy is the leading cause of mortality for the most prevalent inherited ataxia, Friedreich’s ataxia (FA). Deficient expression of the mitochondrial protein frataxin that is crucial for mitochondrial iron metabolism is the cause of FA, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9819962c063da8cf8fb48e0328da9515
https://doi.org/10.1016/j.freeradbiomed.2018.10.346
https://doi.org/10.1016/j.freeradbiomed.2018.10.346
Autor:
Des R. Richardson, Bronwyn E. Brown, Clare L. Hawkins, Michael L.-H. Huang, Shannon Chiang, Amy Anzovino
Publikováno v:
Free Radical Biology and Medicine. 120:S35
The transcription factor, nuclear factor-erythroid 2-related factor-2 (Nrf2), is the master regulator of antioxidant response. Decreased Nrf2 expression was previously reported in studies with models of the neuro-and cardio-degenerative disease, Frie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6bb4cb62c5ecf3950b42845e156c4ad
https://doi.org/10.1016/j.freeradbiomed.2018.04.120
https://doi.org/10.1016/j.freeradbiomed.2018.04.120