Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Bronwyn A. O'Brien"'
Autor:
James Favaloro, Christian E. Bryant, Edward Abadir, Samuel Gardiner, Shihong Yang, Tracy King, Najah Nassif, Bronwyn A. O’Brien, Lisa M. Sedger, Richard Boyle, Douglas E. Joshua, Joy Ho P.
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/47d7ff770d1f4135939bd321809ea522
Publikováno v:
Cells, Vol 11, Iss 14, p 2145 (2022)
Type 1 diabetes is a chronic illness in which the native beta (β)-cell population responsible for insulin release has been the subject of autoimmune destruction. This condition requires patients to frequently measure their blood glucose concentratio
Externí odkaz:
https://doaj.org/article/f3d9fb1800984723932c217a39c01e69
Autor:
Que T. La, Binhai Ren, Grant J. Logan, Sharon C. Cunningham, Neeta Khandekar, Najah T. Nassif, Bronwyn A. O’Brien, Ian E. Alexander, Ann M. Simpson
Publikováno v:
Cells, Vol 9, Iss 10, p 2227 (2020)
Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of
Externí odkaz:
https://doaj.org/article/f8c03c105c804188a1339d6c7227bb54
Autor:
Binhai Ren, Chang Tao, Margaret Anne Swan, Nichole Joachim, Rosetta Martiniello-Wilks, Najah T. Nassif, Bronwyn A. O’Brien, Ann M. Simpson
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 4, p 534 (2016)
Due to the limitations of current treatment regimes, gene therapy is a promising strategy being explored to correct blood glucose concentrations in diabetic patients. In the current study, we used a retroviral vector to deliver either the human insul
Externí odkaz:
https://doaj.org/article/03818e0b2f3d4cb5a97ff934fae7d312
Publikováno v:
Molecular Cloning ISBN: 9781803554501
Molecular Cloning
Molecular Cloning
Developments in gene therapy, coupled with advances in genome sequencing and a greater understanding of DNA sequences, have given rise to an exciting area of research. The use of viral vectors in gene therapy has become a very promising and fast-emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b094e6ce6073633183cf308b83951f08
https://doi.org/10.5772/intechopen.102559
https://doi.org/10.5772/intechopen.102559
Autor:
Joyce To, Nady Braidy, Mark W. Robinson, Tsz Y Mok, Inah Camaya, Bronwyn A. O'Brien, Maria E. Lund, Jerran Santos, Sheila Donnelly
Publikováno v:
Camaya, I, Mok, T, Lund, M, To, J, Braidy, N, Robinson, M W, Santos, J, O'Brien, B & Donnelly, S 2021, ' The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells ', Journal of Molecular Medicine . https://doi.org/10.1007/s00109-021-02122-x
Type 1 diabetes (T1D) is an autoimmune disease characterised by the destruction of the insulin-producing beta (β)-cells within the pancreatic islets. We have previously identified a novel parasite-derived molecule, termed Fasciola hepatica helminth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0708c8435cf4707d19599bff8c2ea28
https://hdl.handle.net/10453/150173
https://hdl.handle.net/10453/150173
Autor:
Theresa C. Sutherland, Alison Ricafrente, Katarina Gomola, Bronwyn A. O'Brien, Catherine A. Gorrie
It has been reported that children may respond better than adults to a spinal cord injury (SCI) of similar severity. There are known biomechanical differences in the developing spinal cord that may contribute to this “infant lesion effect,” but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d354ad2fbfb79ba86982628b6a494eb2
https://hdl.handle.net/10453/153079
https://hdl.handle.net/10453/153079
Autor:
Bronwyn A. O'Brien, Grant J Logan, Ann M. Simpson, Binhai Ren, Que T. La, Najah T. Nassif, Ian E. Alexander, Neeta Khandekar, Sharon C. Cunningham
Publikováno v:
Cells
Volume 9
Issue 10
Cells, Vol 9, Iss 2227, p 2227 (2020)
Volume 9
Issue 10
Cells, Vol 9, Iss 2227, p 2227 (2020)
Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of
Autor:
Valery Combes, Bronwyn A. O'Brien, Bernadette M. Saunders, Michael Johnson, Sheila Donnelly, Catherine Burke, Wilhelmina M. Huston, Maurizio Labbate, Natalia Tiberti
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-6 (2017)
Parasites & Vectors
Parasites & Vectors
© 2017 The Author(s). A systematic analysis of 240 causes of death in 2013 revealed that parasitic diseases were responsible for more than one million deaths. The vast majority of these fatalities resulted from protozoan infections presenting with n
Autor:
Sharon C. Cunningham, Bronwyn A. O'Brien, Grant J Logan, Binhai Ren, Ann M. Simpson, Najah T. Nassif, Ian E. Alexander, Neeta Khandekar, Que T. La
Publikováno v:
Diabetes. 68
Previously we introduced furin-cleavable human insulin (INSFUR) to the livers in several animal models using a lentiviral vector. Reversal of diabetes with normal glucose tolerance and pancreatic transdifferentiation was seen. The aim of the present