Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bronwen Naudé"'
Malaria is the major parasitic disease in tropical developing countries, causing approximately 300 to 500 million febrile illnesses and at least 1.2 million deaths each year. Current antimalarial drugs and mosquito control programs constitute importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66927b86acce172cae43b555a4e4ee6
https://doi.org/10.1128/9781555817572.ch30
https://doi.org/10.1128/9781555817572.ch30
Autor:
Amar Bir Singh Sidhu, Bronwen Naudé, Kirk W. Deitsch, Angela K. Talley, Takashi Nomura, Roland A. Cooper, Sergey M. Dzekunov, Lyann M. B. Ursos, David A. Fidock, John C. Wootton, Paul D. Roepe, Thomas E. Wellems, Xin-zhuan Su, Michael T. Ferdig
Publikováno v:
Molecular Cell. 6:861-871
The determinant of verapamil-reversible chloroquine resistance (CQR) in a Plasmodium falciparum genetic cross maps to a 36 kb segment of chromosome 7. This segment harbors a 13-exon gene, pfcrt, having point mutations that associate completely with C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0068647106f873f7c31a86e5da9af8ed
https://doi.org/10.1016/s1097-2765(05)00077-8
https://doi.org/10.1016/s1097-2765(05)00077-8
Autor:
Juliana M. Sá, Marcio Massao Yamamoto, Mauro F Azevedo, Bronwen Naudé, Carmen Fernandez-Becerra, Thomas E. Wellems, Janni Papakrivos, Hernando A. del Portillo
Publikováno v:
Molecular and biochemical parasitology. 150(2)
Chloroquine resistance in Plasmodium vivax threatens the use of this drug as first-line treatment for millions of people infected each year worldwide. Unlike Plasmodium falciparum, in which chloroquine resistance is associated with mutations in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31f19347de50fe380f198c6f9469119
https://pubmed.ncbi.nlm.nih.gov/16987557
https://pubmed.ncbi.nlm.nih.gov/16987557
Chloroquine resistance in Plasmodium falciparum malaria results from mutations in PfCRT, a member of a unique family of transporters present in apicomplexan parasites and Dictyostelium discoideum. Mechanisms that have been proposed to explain chloroq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc0e91df0402913635613755e312c19
https://europepmc.org/articles/PMC1779819/
https://europepmc.org/articles/PMC1779819/