Zobrazeno 1 - 10 of 81 pro vyhledávání: '"Bronwen Alice James Evans"'
1
The effect of nitrogen containing bisphosphonates, zoledronate and alendronate, on the production of pro-angiogenic factors by osteoblastic cells
Autor: S. Ishtiaq, Carole Elford, S. Edwards, Bronwen Alice James Evans, Arun Sankaralingam, Ignac Fogelman, Michelle L. Frost, Geeta Hampson
Publikováno v: Cytokine. 71:154-160
Bisphosphonates (BPs) have been shown to influence angiogenesis. This may contribute to BP-associated side-effects such as osteonecrosis of the jaw (ONJ) or atypical femoral fractures (AFF). The effect of BPs on the production of angiogenic factors b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fa7c09bdb6fb03beffcdf453bd9b0d
https://doi.org/10.1016/j.cyto.2014.10.025
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2
Knockdown of EPHA1 Using CRISPR/CAS9 Suppresses Aggressive Properties of Ovarian Cancer Cells
Autor: Wen Guo Jiang, Yuxin Cui, Flamini, B O Wu, Deshan Zhou, Bronwen Alice James Evans
Publikováno v: Anticancer Research. 37
Background/Aim: Overexpression of erythropoietin-producing hepatocellular A1 (EPHA1), a member of the EPH super family, is frequently observed in various cancer types. The dysregulated interaction of EPHA1 with its ligand Ephrin A1 has been linked to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189616b4ce4e93c939f4684a1643f1a0
https://doi.org/10.21873/anticanres.11836
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3
Does adenosine play a role in bone formation, resorption and repair?
Autor: Bronwen Alice James Evans
Publikováno v: Purinergic Signalling. 8:177-180
There has been increasing interest recently in the role purinergic signalling in the physiology and pathophysiology of musculoskeletal tissues, especially bone. Whereas the role of ATP in bone metabolism [1, 2] has been revealed to some extent and qu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c335880462cd9a7caf8d22d46584d23c
https://doi.org/10.1007/s11302-012-9317-4
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4
Adenosine receptor subtype expression and activation influence the differentiation of mesenchymal stem cells to osteoblasts and adipocytes
Autor: Borzo Gharibi, Jack Ham, Anju Ann Abraham, Bronwen Alice James Evans
Publikováno v: Journal of Bone and Mineral Research. 26:2112-2124
Osteoblasts and adipocytes differentiate from a common precursor cell, the mesenchymal stem cell (MSC). Adenosine is known to signal via four adenosine receptor subtypes, and significantly, recent findings indicate that these may play a role in MSC d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbe2606812f63ddee7f1d562d3dd130
https://doi.org/10.1002/jbmr.424
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5
The influence of leptin on trabecular architecture and marrow adiposity in GH-deficient rats
Autor: Evelien F. Gevers, Mark Perry, Amy Elizabeth Stevenson, Liam David Morgan, Bronwen Alice James Evans, Rebecca C Kench, Melanie J. Bull, Rebecca E Fox, Timothy N. C. Wells
Publikováno v: Journal of Endocrinology. 208:69-79
The relationship between the degree of GH deficiency and impaired bone integrity is not simple and may be influenced by related endocrine variables. To test the hypothesis that elevated adiposity and hyperleptinaemia are contributory factors, we quan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9955935fcce886cd8c8349149c6c91
https://doi.org/10.1677/joe-10-0178
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6
ASBMR 29th Annual Meeting
Autor: Pablo Reviriego, Kenneth Taylor Wann, Bronwen Alice James Evans, Anthony K. Campbell, Neil C. Henney, Baochun Li
Publikováno v: Journal of Bone and Mineral Research. 22:s152-s201
This free journal suppl. entitled: Supplement: 30th ASBMR Annual Meeting Advancing The Future
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fba26762130a628c52b5b3a0bc17d47e
https://doi.org/10.1002/jbmr.5650221405
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7
Does adiposity status influence femoral cortical strength in rodent models of growth hormone deficiency?
Autor: Evelien F. Gevers, Timothy N. C. Wells, Muna Mustafa El-Kasti, John J. Kopchick, Samuel Lewin Evans, Bronwen Alice James Evans, Amy Elizabeth Stevenson, Carole Elford, Karen T. Coschigano, Robert McLeod, Mark Perry
Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 296:E147-E156
Growth hormone (GH)-deficiency is usually associated with elevated adiposity, hyperleptinemia, and increased fracture risk. Since leptin is thought to enhance cortical bone formation, we have investigated the contribution of elevated adiposity and hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6791d1679be300194a2665614546d185
https://doi.org/10.1152/ajpendo.90689.2008
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10
AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis
Autor: Bronwen Alice James Evans, Ann K Harvey, Deborah Jane Mason, Cleo Bonnet, Sophie Jane Gilbert, Anwen Sian Williams
Publikováno v: Annals of the Rheumatic Diseases
ObjectivesSynovial fluid glutamate concentrations increase in arthritis. Activation of kainate (KA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors (GluRs) increase interleukin-6 (IL-6) release and cause arthritic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c593ab6c3d8aeefe8b63ee5d212d9cee
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